These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 21768522)

  • 1. WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.
    Bergaya S; Faure S; Baudrie V; Rio M; Escoubet B; Bonnin P; Henrion D; Loirand G; Achard JM; Jeunemaitre X; Hadchouel J
    Hypertension; 2011 Sep; 58(3):439-45. PubMed ID: 21768522
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin II.
    Zeniya M; Sohara E; Kita S; Iwamoto T; Susa K; Mori T; Oi K; Chiga M; Takahashi D; Yang SS; Lin SH; Rai T; Sasaki S; Uchida S
    Hypertension; 2013 Nov; 62(5):872-8. PubMed ID: 24019400
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.
    Susa K; Kita S; Iwamoto T; Yang SS; Lin SH; Ohta A; Sohara E; Rai T; Sasaki S; Alessi DR; Uchida S
    Clin Exp Nephrol; 2012 Aug; 16(4):530-8. PubMed ID: 22294159
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction.
    Tanoue A; Nasa Y; Koshimizu T; Shinoura H; Oshikawa S; Kawai T; Sunada S; Takeo S; Tsujimoto G
    J Clin Invest; 2002 Mar; 109(6):765-75. PubMed ID: 11901185
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction.
    Yang SS; Lo YF; Wu CC; Lin SW; Yeh CJ; Chu P; Sytwu HK; Uchida S; Sasaki S; Lin SH
    J Am Soc Nephrol; 2010 Nov; 21(11):1868-77. PubMed ID: 20813865
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cotransporters, WNKs and hypertension: an update.
    Flatman PW
    Curr Opin Nephrol Hypertens; 2008 Mar; 17(2):186-92. PubMed ID: 18277153
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
    Vitari AC; Thastrup J; Rafiqi FH; Deak M; Morrice NA; Karlsson HK; Alessi DR
    Biochem J; 2006 Jul; 397(1):223-31. PubMed ID: 16669787
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.
    Thastrup JO; Rafiqi FH; Vitari AC; Pozo-Guisado E; Deak M; Mehellou Y; Alessi DR
    Biochem J; 2012 Jan; 441(1):325-37. PubMed ID: 22032326
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models.
    Liu Z; Xie J; Wu T; Truong T; Auchus RJ; Huang CL
    Hum Mol Genet; 2011 Mar; 20(5):855-66. PubMed ID: 21131289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.
    Kikuchi E; Mori T; Zeniya M; Isobe K; Ishigami-Yuasa M; Fujii S; Kagechika H; Ishihara T; Mizushima T; Sasaki S; Sohara E; Rai T; Uchida S
    J Am Soc Nephrol; 2015 Jul; 26(7):1525-36. PubMed ID: 25377078
    [TBL] [Abstract][Full Text] [Related]  

  • 11. WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells.
    Anselmo AN; Earnest S; Chen W; Juang YC; Kim SC; Zhao Y; Cobb MH
    Proc Natl Acad Sci U S A; 2006 Jul; 103(29):10883-8. PubMed ID: 16832045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Persistent phosphorylation of NKCC1 and WNK1 in the epicenter of the spinal cord following contusion injury.
    Lee HK; Ahmed MM; King KC; Miranpuri GS; Kahle KT; Resnick DK; Sun D
    Spine J; 2014 May; 14(5):777-81. PubMed ID: 24239489
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.
    Sengupta S; Tu SW; Wedin K; Earnest S; Stippec S; Luby-Phelps K; Cobb MH
    J Biol Chem; 2012 Nov; 287(45):37868-79. PubMed ID: 22989884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of the Na-K-2Cl cotransporter NKCC1 on systemic blood pressure and smooth muscle tone.
    Garg P; Martin CF; Elms SC; Gordon FJ; Wall SM; Garland CJ; Sutliff RL; O'Neill WC
    Am J Physiol Heart Circ Physiol; 2007 May; 292(5):H2100-5. PubMed ID: 17259435
    [TBL] [Abstract][Full Text] [Related]  

  • 15. With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters.
    Mercado A; de Los Heros P; Melo Z; Chávez-Canales M; Murillo-de-Ozores AR; Moreno E; Bazúa-Valenti S; Vázquez N; Hadchouel J; Gamba G
    Am J Physiol Cell Physiol; 2016 Jul; 311(1):C54-66. PubMed ID: 27170636
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
    Gagnon KB; England R; Delpire E
    Cell Physiol Biochem; 2007; 20(1-4):131-42. PubMed ID: 17595523
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stimulation of human and mouse erythrocyte Na(+)-K(+)-2Cl(-) cotransport by osmotic shrinkage does not involve AMP-activated protein kinase, but is associated with STE20/SPS1-related proline/alanine-rich kinase activation.
    Sid B; Miranda L; Vertommen D; Viollet B; Rider MH
    J Physiol; 2010 Jul; 588(Pt 13):2315-28. PubMed ID: 20442269
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Vascular alpha-1D-adrenoceptors are overexpressed in aorta of the aryl hydrocarbon receptor null mouse: role of increased angiotensin II.
    Villalobos-Molina R; Vázquez-Cuevas FG; López-Guerrero JJ; Figueroa-García MC; Gallardo-Ortiz IA; Ibarra M; Rodríguez-Sosa M; Gonzalez FJ; Elizondo G
    Auton Autacoid Pharmacol; 2008; 28(2-3):61-7. PubMed ID: 18598287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple pathways for protein phosphatase 1 (PP1) regulation of Na-K-2Cl cotransporter (NKCC1) function: the N-terminal tail of the Na-K-2Cl cotransporter serves as a regulatory scaffold for Ste20-related proline/alanine-rich kinase (SPAK) AND PP1.
    Gagnon KB; Delpire E
    J Biol Chem; 2010 May; 285(19):14115-21. PubMed ID: 20223824
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of WNK1-mediated potassium channels in the sexual dimorphism of blood pressure.
    Yu G; Cheng M; Wang W; Zhao R; Liu Z
    Biochem Biophys Res Commun; 2017 Apr; 485(2):255-260. PubMed ID: 28237360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.