BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

415 related articles for article (PubMed ID: 21769563)

  • 1. Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells.
    Zhang ZM; Yang XQ; Wang D; Wang G; Yang ZZ; Qing Y; Yang ZX; Li MX; Xiang DB
    Cell Biochem Biophys; 2011 Dec; 61(3):561-72. PubMed ID: 21769563
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease.
    Nguyen LH; Barsky D; Erzberger JP; Wilson DM
    J Mol Biol; 2000 May; 298(3):447-59. PubMed ID: 10772862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.
    Robertson KA; Bullock HA; Xu Y; Tritt R; Zimmerman E; Ulbright TM; Foster RS; Einhorn LH; Kelley MR
    Cancer Res; 2001 Mar; 61(5):2220-5. PubMed ID: 11280790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. APE1 modulates cellular responses to organophosphate pesticide-induced oxidative damage in non-small cell lung carcinoma A549 cells.
    Thakur S; Dhiman M; Mantha AK
    Mol Cell Biochem; 2018 Apr; 441(1-2):201-216. PubMed ID: 28887667
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M; Kelley MR
    Anticancer Res; 2004; 24(4):2127-34. PubMed ID: 15330152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells.
    Wang D; Xiang DB; Yang XQ; Chen LS; Li MX; Zhong ZY; Zhang YS
    Lung Cancer; 2009 Dec; 66(3):298-304. PubMed ID: 19324449
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA.
    Marenstein DR; Wilson DM; Teebor GW
    DNA Repair (Amst); 2004 May; 3(5):527-33. PubMed ID: 15084314
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo.
    Xiang DB; Chen ZT; Wang D; Li MX; Xie JY; Zhang YS; Qing Y; Li ZP; Xie J
    Cancer Gene Ther; 2008 Oct; 15(10):625-35. PubMed ID: 18535621
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Probing conformational changes in Ape1 during the progression of base excision repair.
    Yu E; Gaucher SP; Hadi MZ
    Biochemistry; 2010 May; 49(18):3786-96. PubMed ID: 20377204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation.
    Kladova OA; Bazlekowa-Karaban M; Baconnais S; Piétrement O; Ishchenko AA; Matkarimov BT; Iakovlev DA; Vasenko A; Fedorova OS; Le Cam E; Tudek B; Kuznetsov NA; Saparbaev M
    DNA Repair (Amst); 2018 Apr; 64():10-25. PubMed ID: 29475157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
    Zawahir Z; Dayam R; Deng J; Pereira C; Neamati N
    J Med Chem; 2009 Jan; 52(1):20-32. PubMed ID: 19072053
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [nm23-H1 gene inhibits lung cancer cell invasion through down-regulation of PKC signal pathway].
    Nie Q; Zhou QH; Zhu W; Liu LX; Fu JK; Li DB; Li Y; Che GW
    Zhonghua Zhong Liu Za Zhi; 2006 May; 28(5):334-6. PubMed ID: 17044994
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.
    Daviet S; Couvé-Privat S; Gros L; Shinozuka K; Ide H; Saparbaev M; Ishchenko AA
    DNA Repair (Amst); 2007 Jan; 6(1):8-18. PubMed ID: 16978929
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing.
    Ma W; Chen J; Xue X; Wang Z; Liu H; Wang T; Bai Y; Tang SC; Zhou Q
    Biochem Biophys Res Commun; 2008 Jul; 371(3):425-30. PubMed ID: 18440302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1].
    Che GW; Zhou QH; Zhu W; Wang YP; Qin Y; Liu LX; Chen XH; Sun YL; Sun ZF
    Ai Zheng; 2005 Mar; 24(3):278-84. PubMed ID: 15757527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ape1 abasic endonuclease activity is regulated by magnesium and potassium concentrations and is robust on alternative DNA structures.
    Wilson DM
    J Mol Biol; 2005 Feb; 345(5):1003-14. PubMed ID: 15644200
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1.
    Li M; Vascotto C; Xu S; Dai N; Qing Y; Zhong Z; Tell G; Wang D
    Free Radic Biol Med; 2012 Jul; 53(2):237-48. PubMed ID: 22580151
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors.
    Bobola MS; Finn LS; Ellenbogen RG; Geyer JR; Berger MS; Braga JM; Meade EH; Gross ME; Silber JR
    Clin Cancer Res; 2005 Oct; 11(20):7405-14. PubMed ID: 16243814
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Subcellular localization of apurinic endonuclease 1 promotes lung tumor aggressiveness via NF-kappaB activation.
    Wu HH; Cheng YW; Chang JT; Wu TC; Liu WS; Chen CY; Lee H
    Oncogene; 2010 Jul; 29(30):4330-40. PubMed ID: 20498636
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression of nucleoside diphosphate/kinase A/nm23-H1 protein in human lung tumors: association with tumor progression in squamous carcinoma.
    Gazzeri S; Brambilla E; Negoescu A; Thoraval D; Veron M; Moro D; Brambilla C
    Lab Invest; 1996 Jan; 74(1):158-67. PubMed ID: 8569178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.