These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

422 related articles for article (PubMed ID: 21769563)

  • 1. Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells.
    Zhang ZM; Yang XQ; Wang D; Wang G; Yang ZZ; Qing Y; Yang ZX; Li MX; Xiang DB
    Cell Biochem Biophys; 2011 Dec; 61(3):561-72. PubMed ID: 21769563
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease.
    Nguyen LH; Barsky D; Erzberger JP; Wilson DM
    J Mol Biol; 2000 May; 298(3):447-59. PubMed ID: 10772862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.
    Robertson KA; Bullock HA; Xu Y; Tritt R; Zimmerman E; Ulbright TM; Foster RS; Einhorn LH; Kelley MR
    Cancer Res; 2001 Mar; 61(5):2220-5. PubMed ID: 11280790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. APE1 modulates cellular responses to organophosphate pesticide-induced oxidative damage in non-small cell lung carcinoma A549 cells.
    Thakur S; Dhiman M; Mantha AK
    Mol Cell Biochem; 2018 Apr; 441(1-2):201-216. PubMed ID: 28887667
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M; Kelley MR
    Anticancer Res; 2004; 24(4):2127-34. PubMed ID: 15330152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells.
    Wang D; Xiang DB; Yang XQ; Chen LS; Li MX; Zhong ZY; Zhang YS
    Lung Cancer; 2009 Dec; 66(3):298-304. PubMed ID: 19324449
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA.
    Marenstein DR; Wilson DM; Teebor GW
    DNA Repair (Amst); 2004 May; 3(5):527-33. PubMed ID: 15084314
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo.
    Xiang DB; Chen ZT; Wang D; Li MX; Xie JY; Zhang YS; Qing Y; Li ZP; Xie J
    Cancer Gene Ther; 2008 Oct; 15(10):625-35. PubMed ID: 18535621
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Probing conformational changes in Ape1 during the progression of base excision repair.
    Yu E; Gaucher SP; Hadi MZ
    Biochemistry; 2010 May; 49(18):3786-96. PubMed ID: 20377204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation.
    Kladova OA; Bazlekowa-Karaban M; Baconnais S; Piétrement O; Ishchenko AA; Matkarimov BT; Iakovlev DA; Vasenko A; Fedorova OS; Le Cam E; Tudek B; Kuznetsov NA; Saparbaev M
    DNA Repair (Amst); 2018 Apr; 64():10-25. PubMed ID: 29475157
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
    Zawahir Z; Dayam R; Deng J; Pereira C; Neamati N
    J Med Chem; 2009 Jan; 52(1):20-32. PubMed ID: 19072053
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [nm23-H1 gene inhibits lung cancer cell invasion through down-regulation of PKC signal pathway].
    Nie Q; Zhou QH; Zhu W; Liu LX; Fu JK; Li DB; Li Y; Che GW
    Zhonghua Zhong Liu Za Zhi; 2006 May; 28(5):334-6. PubMed ID: 17044994
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.
    Daviet S; Couvé-Privat S; Gros L; Shinozuka K; Ide H; Saparbaev M; Ishchenko AA
    DNA Repair (Amst); 2007 Jan; 6(1):8-18. PubMed ID: 16978929
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing.
    Ma W; Chen J; Xue X; Wang Z; Liu H; Wang T; Bai Y; Tang SC; Zhou Q
    Biochem Biophys Res Commun; 2008 Jul; 371(3):425-30. PubMed ID: 18440302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1].
    Che GW; Zhou QH; Zhu W; Wang YP; Qin Y; Liu LX; Chen XH; Sun YL; Sun ZF
    Ai Zheng; 2005 Mar; 24(3):278-84. PubMed ID: 15757527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ape1 abasic endonuclease activity is regulated by magnesium and potassium concentrations and is robust on alternative DNA structures.
    Wilson DM
    J Mol Biol; 2005 Feb; 345(5):1003-14. PubMed ID: 15644200
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1.
    Li M; Vascotto C; Xu S; Dai N; Qing Y; Zhong Z; Tell G; Wang D
    Free Radic Biol Med; 2012 Jul; 53(2):237-48. PubMed ID: 22580151
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors.
    Bobola MS; Finn LS; Ellenbogen RG; Geyer JR; Berger MS; Braga JM; Meade EH; Gross ME; Silber JR
    Clin Cancer Res; 2005 Oct; 11(20):7405-14. PubMed ID: 16243814
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Subcellular localization of apurinic endonuclease 1 promotes lung tumor aggressiveness via NF-kappaB activation.
    Wu HH; Cheng YW; Chang JT; Wu TC; Liu WS; Chen CY; Lee H
    Oncogene; 2010 Jul; 29(30):4330-40. PubMed ID: 20498636
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression of nucleoside diphosphate/kinase A/nm23-H1 protein in human lung tumors: association with tumor progression in squamous carcinoma.
    Gazzeri S; Brambilla E; Negoescu A; Thoraval D; Veron M; Moro D; Brambilla C
    Lab Invest; 1996 Jan; 74(1):158-67. PubMed ID: 8569178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.