112 related articles for article (PubMed ID: 21774748)
21. Towards the development of 5-HT₇ ligands combining serotonin-like and arylpiperazine moieties.
Spadoni G; Bedini A; Bartolucci S; Pala D; Mor M; Riccioni T; Borsini F; Cabri W; Celona D; Marzi M; Tarzia G; Rivara S; Minetti P
Eur J Med Chem; 2014 Jun; 80():8-35. PubMed ID: 24763360
[TBL] [Abstract][Full Text] [Related]
22. 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
Chłoń-Rzepa G; Zmudzki P; Zajdel P; Bojarski AJ; Duszyńska B; Nikiforuk A; Tatarczyńska E; Pawłowski M
Bioorg Med Chem; 2007 Aug; 15(15):5239-50. PubMed ID: 17517514
[TBL] [Abstract][Full Text] [Related]
23. Computational approaches to the design of novel 5-HT6 R ligands.
Ivanenkov YA; Majouga AG; Veselov MS; Chufarova NV; Baranovsky SS; Filkov GI
Rev Neurosci; 2014; 25(3):451-67. PubMed ID: 24867282
[TBL] [Abstract][Full Text] [Related]
24. Discovery of 5-HT6 receptor ligands based on virtual HTS.
Tasler S; Kraus J; Wuzik A; Müller O; Aschenbrenner A; Cubero E; Pascual R; Quintana-Ruiz JR; Dordal A; Mercè R; Codony X
Bioorg Med Chem Lett; 2007 Nov; 17(22):6224-9. PubMed ID: 17892934
[TBL] [Abstract][Full Text] [Related]
25. The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease.
Geldenhuys WJ; Van der Schyf CJ
Expert Rev Neurother; 2009 Jul; 9(7):1073-85. PubMed ID: 19589055
[TBL] [Abstract][Full Text] [Related]
26. Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity.
Medina RA; Sallander J; Benhamú B; Porras E; Campillo M; Pardo L; López-Rodríguez ML
J Med Chem; 2009 Apr; 52(8):2384-92. PubMed ID: 19326916
[TBL] [Abstract][Full Text] [Related]
27. Novel aza-analogous ergoline derived scaffolds as potent serotonin 5-HT₆ and dopamine D₂ receptor ligands.
Krogsgaard-Larsen N; Jensen AA; Schrøder TJ; Christoffersen CT; Kehler J
J Med Chem; 2014 Jul; 57(13):5823-8. PubMed ID: 24878269
[TBL] [Abstract][Full Text] [Related]
28. Selective 5-HT6 receptor ligands: progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders.
Heal DJ; Smith SL; Fisas A; Codony X; Buschmann H
Pharmacol Ther; 2008 Feb; 117(2):207-31. PubMed ID: 18068807
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and biological evaluation of novel N
Nirogi RV; Bandyala TR; Gangadasari PR; Khagga M
J Enzyme Inhib Med Chem; 2016; 31(sup1):1-15. PubMed ID: 27806648
[TBL] [Abstract][Full Text] [Related]
30. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.
Hirst WD; Stean TO; Rogers DC; Sunter D; Pugh P; Moss SF; Bromidge SM; Riley G; Smith DR; Bartlett S; Heidbreder CA; Atkins AR; Lacroix LP; Dawson LA; Foley AG; Regan CM; Upton N
Eur J Pharmacol; 2006 Dec; 553(1-3):109-19. PubMed ID: 17069795
[TBL] [Abstract][Full Text] [Related]
31. Design, synthesis, and pharmacological evaluation of piperidin-4-yl amino aryl sulfonamides: novel, potent, selective, orally active, and brain penetrant 5-HT₆ receptor antagonists.
Nirogi R; Shinde A; Daulatabad A; Kambhampati R; Gudla P; Shaik M; Gampa M; Balasubramaniam S; Gangadasari P; Reballi V; Badange R; Bojja K; Subramanian R; Bhyrapuneni G; Muddana N; Jayarajan P
J Med Chem; 2012 Nov; 55(21):9255-69. PubMed ID: 23006002
[TBL] [Abstract][Full Text] [Related]
32. Design, synthesis and pharmacological evaluation of indolylsulfonamide amines as potent and selective 5-HT6 receptor antagonists.
Nirogi RV; Bandyala TR; Reballi V; Konda JB; Daulatabad AV; Khagga M
J Enzyme Inhib Med Chem; 2015 Feb; 30(1):85-97. PubMed ID: 24666297
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and biological evaluation of benzoisothiazole derivatives possessing N,N-dimethylformimidamide group as 5-HT₆ receptor antagonists.
Yoo E; Hayat F; Rhim H; Park Choo HY
Bioorg Med Chem; 2012 Apr; 20(8):2707-12. PubMed ID: 22405919
[TBL] [Abstract][Full Text] [Related]
34. trans-2-Aryl-N,N-dipropylcyclopropylamines: synthesis and interactions with 5-HT(1A) receptors.
Vallgårda J; Appelberg U; Arvidsson LE; Hjorth S; Svensson BE; Hacksell U
J Med Chem; 1996 Mar; 39(7):1485-93. PubMed ID: 8691479
[TBL] [Abstract][Full Text] [Related]
35. Novel quinazolinone derivatives as 5-HT7 receptor ligands.
Na YH; Hong SH; Lee JH; Park WK; Baek DJ; Koh HY; Cho YS; Choo H; Pae AN
Bioorg Med Chem; 2008 Mar; 16(5):2570-8. PubMed ID: 18083580
[TBL] [Abstract][Full Text] [Related]
36. Interaction of chiral MS-245 analogs at h5-HT6 receptors.
Abate C; Kolanos R; Dukat M; Setola V; Roth BL; Glennon RA
Bioorg Med Chem Lett; 2005 Aug; 15(15):3510-3. PubMed ID: 15990303
[TBL] [Abstract][Full Text] [Related]
37. New serotonin 5-HT(6) ligands from common feature pharmacophore hypotheses.
Kim HJ; Doddareddy MR; Choo H; Cho YS; No KT; Park WK; Pae AN
J Chem Inf Model; 2008 Jan; 48(1):197-206. PubMed ID: 18044950
[TBL] [Abstract][Full Text] [Related]
38. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
Tapia I; Alonso-Cires L; López-Tudanca PL; Mosquera R; Labeaga L; Innerárity A; Orjales A
J Med Chem; 1999 Jul; 42(15):2870-80. PubMed ID: 10425096
[TBL] [Abstract][Full Text] [Related]
39. Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonists.
Cole DC; Lennox WJ; Stock JR; Ellingboe JW; Mazandarani H; Smith DL; Zhang G; Tawa GJ; Schechter LE
Bioorg Med Chem Lett; 2005 Nov; 15(21):4780-5. PubMed ID: 16125933
[TBL] [Abstract][Full Text] [Related]
40. Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
López-Rodríguez ML; Porras E; Morcillo MJ; Benhamú B; Soto LJ; Lavandera JL; Ramos JA; Olivella M; Campillo M; Pardo L
J Med Chem; 2003 Dec; 46(26):5638-50. PubMed ID: 14667218
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]