148 related articles for article (PubMed ID: 21775054)
1. Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: more than just AKT inhibition.
Sun H; Yu T; Li J
Cancer Lett; 2011 Nov; 310(1):118-28. PubMed ID: 21775054
[TBL] [Abstract][Full Text] [Related]
2. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
Rahmani M; Reese E; Dai Y; Bauer C; Payne SG; Dent P; Spiegel S; Grant S
Cancer Res; 2005 Mar; 65(6):2422-32. PubMed ID: 15781658
[TBL] [Abstract][Full Text] [Related]
3. The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
Chiarini F; Del Sole M; Mongiorgi S; Gaboardi GC; Cappellini A; Mantovani I; Follo MY; McCubrey JA; Martelli AM
Leukemia; 2008 Jun; 22(6):1106-16. PubMed ID: 18385752
[TBL] [Abstract][Full Text] [Related]
4. Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro.
Chen MB; Wu XY; Tao GQ; Liu CY; Chen J; Wang LQ; Lu PH
Int J Cancer; 2012 Dec; 131(11):2487-98. PubMed ID: 22438101
[TBL] [Abstract][Full Text] [Related]
5. Akt involvement in paclitaxel chemoresistance of human ovarian cancer cells.
Kim SH; Juhnn YS; Song YS
Ann N Y Acad Sci; 2007 Jan; 1095():82-9. PubMed ID: 17404021
[TBL] [Abstract][Full Text] [Related]
6. Elesclomol, counteracted by Akt survival signaling, enhances the apoptotic effect of chemotherapy drugs in breast cancer cells.
Qu Y; Wang J; Sim MS; Liu B; Giuliano A; Barsoum J; Cui X
Breast Cancer Res Treat; 2010 Jun; 121(2):311-21. PubMed ID: 19609669
[TBL] [Abstract][Full Text] [Related]
7. Perifosine sensitizes UVB-induced apoptosis in skin cells: new implication of skin cancer prevention?
Ji C; Yang YL; Yang Z; Tu Y; Cheng L; Chen B; Xia JP; Sun WL; Su ZL; He L; Bi ZG
Cell Signal; 2012 Sep; 24(9):1781-9. PubMed ID: 22584119
[TBL] [Abstract][Full Text] [Related]
8. Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFκB pathway.
Yang YI; Lee KT; Park HJ; Kim TJ; Choi YS; Shih IeM; Choi JH
Carcinogenesis; 2012 Dec; 33(12):2488-98. PubMed ID: 23027625
[TBL] [Abstract][Full Text] [Related]
9. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Ou YC; Yang CR; Cheng CL; Raung SL; Hung YY; Chen CJ
Eur J Pharmacol; 2007 Jun; 563(1-3):49-60. PubMed ID: 17341418
[TBL] [Abstract][Full Text] [Related]
10. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
Li CM; Narayanan R; Lu Y; Hurh E; Coss CC; Barrett CM; Miller DD; Dalton JT
Int J Oncol; 2010 Oct; 37(4):1023-30. PubMed ID: 20811725
[TBL] [Abstract][Full Text] [Related]
11. Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells.
Chen MB; Zhang Y; Wei MX; Shen W; Wu XY; Yao C; Lu PH
Cell Signal; 2013 Oct; 25(10):1993-2002. PubMed ID: 23712032
[TBL] [Abstract][Full Text] [Related]
12. Perifosine induces cell apoptosis in human osteosarcoma cells: new implication for osteosarcoma therapy?
Yao C; Wei JJ; Wang ZY; Ding HM; Li D; Yan SC; Yang YJ; Gu ZP
Cell Biochem Biophys; 2013 Mar; 65(2):217-27. PubMed ID: 23015227
[TBL] [Abstract][Full Text] [Related]
13. Paclitaxel (Taxol) upregulates expression of functional interleukin-6 in human ovarian cancer cells through multiple signaling pathways.
Wang TH; Chan YH; Chen CW; Kung WH; Lee YS; Wang ST; Chang TC; Wang HS
Oncogene; 2006 Aug; 25(35):4857-66. PubMed ID: 16547493
[TBL] [Abstract][Full Text] [Related]
14. Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
Papa V; Tazzari PL; Chiarini F; Cappellini A; Ricci F; Billi AM; Evangelisti C; Ottaviani E; Martinelli G; Testoni N; McCubrey JA; Martelli AM
Leukemia; 2008 Jan; 22(1):147-60. PubMed ID: 17928881
[TBL] [Abstract][Full Text] [Related]
15. The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
Kumar A; Fillmore HL; Kadian R; Broaddus WC; Tye GW; Van Meter TE
Mol Cancer Res; 2009 Nov; 7(11):1813-21. PubMed ID: 19887560
[TBL] [Abstract][Full Text] [Related]
16. alpha-TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells.
Yu W; Shun MC; Anderson K; Chen H; Sanders BG; Kline K
Apoptosis; 2006 Oct; 11(10):1813-23. PubMed ID: 16850165
[TBL] [Abstract][Full Text] [Related]
17. Inhibiting the mTOR pathway synergistically enhances cytotoxicity in ovarian cancer cells induced by etoposide through upregulation of c-Jun.
Itamochi H; Oishi T; Shimada M; Sato S; Uegaki K; Naniwa J; Sato S; Nonaka M; Terakawa N; Kigawa J; Harada T
Clin Cancer Res; 2011 Jul; 17(14):4742-50. PubMed ID: 21610153
[TBL] [Abstract][Full Text] [Related]
18. Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.
Watson JL; Greenshields A; Hill R; Hilchie A; Lee PW; Giacomantonio CA; Hoskin DW
Mol Carcinog; 2010 Jan; 49(1):13-24. PubMed ID: 19676105
[TBL] [Abstract][Full Text] [Related]
19. Potentiation of paclitaxel-induced apoptosis by galectin-13 overexpression via activation of Ask-1-p38-MAP kinase and JNK/SAPK pathways and suppression of Akt and ERK1/2 activation in U-937 human macrophage cells.
Boronkai A; Bellyei S; Szigeti A; Pozsgai E; Bognar Z; Sumegi B; Gallyas F
Eur J Cell Biol; 2009 Dec; 88(12):753-63. PubMed ID: 19717209
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways.
Zhang L; Wang H; Xu J; Zhu J; Ding K
Toxicol Lett; 2014 Aug; 228(3):248-59. PubMed ID: 24875536
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
