These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 21779303)

  • 1. X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery.
    Cooper DR; Porebski PJ; Chruszcz M; Minor W
    Expert Opin Drug Discov; 2011 Aug; 6(8):771-782. PubMed ID: 21779303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The future of crystallography in drug discovery.
    Zheng H; Hou J; Zimmerman MD; Wlodawer A; Minor W
    Expert Opin Drug Discov; 2014 Feb; 9(2):125-37. PubMed ID: 24372145
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The current role and evolution of X-ray crystallography in drug discovery and development.
    Bijak V; Szczygiel M; Lenkiewicz J; Gucwa M; Cooper DR; Murzyn K; Minor W
    Expert Opin Drug Discov; 2023; 18(11):1221-1230. PubMed ID: 37592849
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recent progress in robot-based systems for crystallography and their contribution to drug discovery.
    Ferrer JL; Larive NA; Bowler MW; Nurizzo D
    Expert Opin Drug Discov; 2013 Jul; 8(7):835-47. PubMed ID: 23656378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. '
    Chakraborti S; Hatti K; Srinivasan N
    Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34202053
    [TBL] [Abstract][Full Text] [Related]  

  • 6. X-ray crystallography over the past decade for novel drug discovery - where are we heading next?
    Zheng H; Handing KB; Zimmerman MD; Shabalin IG; Almo SC; Minor W
    Expert Opin Drug Discov; 2015; 10(9):975-89. PubMed ID: 26177814
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein X-ray Crystallography and Drug Discovery.
    Maveyraud L; Mourey L
    Molecules; 2020 Feb; 25(5):. PubMed ID: 32106588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
    Crider K; Williams J; Qi YP; Gutman J; Yeung L; Mai C; Finkelstain J; Mehta S; Pons-Duran C; Menéndez C; Moraleda C; Rogers L; Daniels K; Green P
    Cochrane Database Syst Rev; 2022 Feb; 2(2022):. PubMed ID: 36321557
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Counting on Fragment Based Drug Design Approach for Drug Discovery.
    Kashyap A; Singh PK; Silakari O
    Curr Top Med Chem; 2018; 18(27):2284-2293. PubMed ID: 30499406
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The critical role of QM/MM X-ray refinement and accurate tautomer/protomer determination in structure-based drug design.
    Borbulevych OY; Martin RI; Westerhoff LM
    J Comput Aided Mol Des; 2021 Apr; 35(4):433-451. PubMed ID: 33108589
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Domain-based small molecule binding site annotation.
    Snyder KA; Feldman HJ; Dumontier M; Salama JJ; Hogue CW
    BMC Bioinformatics; 2006 Mar; 7():152. PubMed ID: 16545112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive.
    Burley SK; Berman HM; Kleywegt GJ; Markley JL; Nakamura H; Velankar S
    Methods Mol Biol; 2017; 1607():627-641. PubMed ID: 28573592
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combining NMR and X-ray crystallography in fragment-based drug discovery: discovery of highly potent and selective BACE-1 inhibitors.
    Wyss DF; Wang YS; Eaton HL; Strickland C; Voigt JH; Zhu Z; Stamford AW
    Top Curr Chem; 2012; 317():83-114. PubMed ID: 21647837
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ligand-protein docking: cancer research at the interface between biology and chemistry.
    Glen RC; Allen SC
    Curr Med Chem; 2003 May; 10(9):763-7. PubMed ID: 12678780
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Macromolecular structures: Quality assessment and biological interpretation.
    Salunke DM; Nair DT
    IUBMB Life; 2017 Aug; 69(8):563-571. PubMed ID: 28497559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Validation of Protein-Ligand Crystal Structure Models: Small Molecule and Peptide Ligands.
    Pozharski E; Deller MC; Rupp B
    Methods Mol Biol; 2017; 1607():611-625. PubMed ID: 28573591
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comprehensive Assessment of Torsional Strain in Crystal Structures of Small Molecules and Protein-Ligand Complexes using ab Initio Calculations.
    Rai BK; Sresht V; Yang Q; Unwalla R; Tu M; Mathiowetz AM; Bakken GA
    J Chem Inf Model; 2019 Oct; 59(10):4195-4208. PubMed ID: 31573196
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced validation of small-molecule ligands and carbohydrates in the Protein Data Bank.
    Feng Z; Westbrook JD; Sala R; Smart OS; Bricogne G; Matsubara M; Yamada I; Tsuchiya S; Aoki-Kinoshita KF; Hoch JC; Kurisu G; Velankar S; Burley SK; Young JY
    Structure; 2021 Apr; 29(4):393-400.e1. PubMed ID: 33657417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches.
    Hough MA; Prischi F; Worrall JAR
    Front Mol Biosci; 2023; 10():1113762. PubMed ID: 36756363
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simplified quality assessment for small-molecule ligands in the Protein Data Bank.
    Shao C; Westbrook JD; Lu C; Bhikadiya C; Peisach E; Young JY; Duarte JM; Lowe R; Wang S; Rose Y; Feng Z; Burley SK
    Structure; 2022 Feb; 30(2):252-262.e4. PubMed ID: 35026162
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.