BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

818 related articles for article (PubMed ID: 21779496)

  • 1. Raf family kinases: old dogs have learned new tricks.
    Matallanas D; Birtwistle M; Romano D; Zebisch A; Rauch J; von Kriegsheim A; Kolch W
    Genes Cancer; 2011 Mar; 2(3):232-60. PubMed ID: 21779496
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A-Raf: A new star of the family of raf kinases.
    An S; Yang Y; Ward R; Liu Y; Guo XX; Xu TR
    Crit Rev Biochem Mol Biol; 2015; 50(6):520-31. PubMed ID: 26508523
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
    Steelman LS; Franklin RA; Abrams SL; Chappell W; Kempf CR; Bäsecke J; Stivala F; Donia M; Fagone P; Nicoletti F; Libra M; Ruvolo P; Ruvolo V; Evangelisti C; Martelli AM; McCubrey JA
    Leukemia; 2011 Jul; 25(7):1080-94. PubMed ID: 21494257
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of Raf Family Is a Milestone in Deciphering the Ras-Mediated Intracellular Signaling Pathway.
    Zhao J; Luo Z
    Int J Mol Sci; 2022 May; 23(9):. PubMed ID: 35563547
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
    Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.
    Roberts PJ; Der CJ
    Oncogene; 2007 May; 26(22):3291-310. PubMed ID: 17496923
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting CRAF kinase in anti-cancer therapy: progress and opportunities.
    Wang P; Laster K; Jia X; Dong Z; Liu K
    Mol Cancer; 2023 Dec; 22(1):208. PubMed ID: 38111008
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ERK and beyond: insights from B-Raf and Raf-1 conditional knockouts.
    Galabova-Kovacs G; Kolbus A; Matzen D; Meissl K; Piazzolla D; Rubiolo C; Steinitz K; Baccarini M
    Cell Cycle; 2006 Jul; 5(14):1514-8. PubMed ID: 16861903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting RAS-RAF-MEK-ERK signaling pathway in human cancer: Current status in clinical trials.
    Song Y; Bi Z; Liu Y; Qin F; Wei Y; Wei X
    Genes Dis; 2023 Jan; 10(1):76-88. PubMed ID: 37013062
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Unraveling the interplay between RAS/RAF/MEK/ERK signaling pathway and autophagy in cancer: From molecular mechanisms to targeted therapy.
    Huang Y; Zhen Y; Chen Y; Sui S; Zhang L
    Biochem Pharmacol; 2023 Nov; 217():115842. PubMed ID: 37802240
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Taming the Hippo: Raf-1 controls apoptosis by suppressing MST2/Hippo.
    O'Neill E; Kolch W
    Cell Cycle; 2005 Mar; 4(3):365-7. PubMed ID: 15701972
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy.
    Degirmenci U; Wang M; Hu J
    Cells; 2020 Jan; 9(1):. PubMed ID: 31941155
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade.
    Avruch J; Khokhlatchev A; Kyriakis JM; Luo Z; Tzivion G; Vavvas D; Zhang XF
    Recent Prog Horm Res; 2001; 56():127-55. PubMed ID: 11237210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation.
    Troppmair J; Bruder JT; Munoz H; Lloyd PA; Kyriakis J; Banerjee P; Avruch J; Rapp UR
    J Biol Chem; 1994 Mar; 269(9):7030-5. PubMed ID: 8120067
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting oncogenic Raf protein-serine/threonine kinases in human cancers.
    Roskoski R
    Pharmacol Res; 2018 Sep; 135():239-258. PubMed ID: 30118796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of the RAF/MEK/ERK Signaling Cascade in Pancreatic Cancer: Recent Advances and Future Perspectives.
    Adamopoulos C; Cave DD; Papavassiliou AG
    Int J Mol Sci; 2024 Jan; 25(3):. PubMed ID: 38338909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oncogenic B-Raf mutations: crystal clear at last.
    Dhillon AS; Kolch W
    Cancer Cell; 2004 Apr; 5(4):303-4. PubMed ID: 15093535
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MEK1/2 inhibitors in the treatment of gynecologic malignancies.
    Miller CR; Oliver KE; Farley JH
    Gynecol Oncol; 2014 Apr; 133(1):128-37. PubMed ID: 24434059
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.
    Chang F; Steelman LS; Lee JT; Shelton JG; Navolanic PM; Blalock WL; Franklin RA; McCubrey JA
    Leukemia; 2003 Jul; 17(7):1263-93. PubMed ID: 12835716
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Roles of targeting Ras/Raf/MEK/ERK signaling pathways in the treatment of esophageal carcinoma].
    Chang YS; Liu JC; Fu HQ; Yu BT; Zou SB; Wu QC; Wan L
    Yao Xue Xue Bao; 2013 May; 48(5):635-41. PubMed ID: 23888683
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.