BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 21782801)

  • 1. Degradation of the GAB1 adaptor by the ubiquitin-proteasome pathway hampers HGF/SF-MET signaling.
    Goormachtigh G; Ji Z; Le Goff A; Fafeur V
    Biochem Biophys Res Commun; 2011 Aug; 411(4):780-5. PubMed ID: 21782801
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair.
    Fan S; Ma YX; Gao M; Yuan RQ; Meng Q; Goldberg ID; Rosen EM
    Mol Cell Biol; 2001 Aug; 21(15):4968-84. PubMed ID: 11438654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-apoptotic role of caspase-cleaved GAB1 adaptor protein in hepatocyte growth factor/scatter factor-MET receptor protein signaling.
    Le Goff A; Ji Z; Leclercq B; Bourette RP; Mougel A; Guerardel C; de Launoit Y; Vicogne J; Goormachtigh G; Fafeur V
    J Biol Chem; 2012 Oct; 287(42):35382-35396. PubMed ID: 22915589
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines.
    Watanabe T; Tsuda M; Makino Y; Ichihara S; Sawa H; Minami A; Mochizuki N; Nagashima K; Tanaka S
    Mol Cancer Res; 2006 Jul; 4(7):499-510. PubMed ID: 16849525
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.
    Garcia-Guzman M; Larsen E; Vuori K
    Oncogene; 2000 Aug; 19(35):4058-65. PubMed ID: 10962563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination.
    Taher TE; Tjin EP; Beuling EA; Borst J; Spaargaren M; Pals ST
    J Immunol; 2002 Oct; 169(7):3793-800. PubMed ID: 12244174
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Grb2-associated binder-1 plays a central role in the hepatocyte growth factor enhancement of hepatoma growth inhibition by K vitamin analog compound 5.
    Wang Z; Ge L; Wang M; Carr BI
    Hepatology; 2007 Dec; 46(6):2003-13. PubMed ID: 18046719
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions.
    Chan PC; Sudhakar JN; Lai CC; Chen HC
    Oncogene; 2010 Feb; 29(5):698-710. PubMed ID: 19881549
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatocyte Growth Factor/scatter factor-induces phosphorylation of cortactin in A431 cells in a Src kinase-independent manner.
    Crostella L; Lidder S; Williams R; Skouteris GG
    Oncogene; 2001 Jun; 20(28):3735-45. PubMed ID: 11439336
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disproportionately high levels of HGF induce the degradation of the c-met receptor through the proteasomal degradation pathway.
    Lee N; Lee J; Lee SH; Kim S; Kim S
    Biochem Biophys Res Commun; 2018 Nov; 505(3):925-930. PubMed ID: 30309648
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met.
    Petrelli A; Gilestro GF; Lanzardo S; Comoglio PM; Migone N; Giordano S
    Nature; 2002 Mar; 416(6877):187-90. PubMed ID: 11894096
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
    Higuchi T; Orita T; Katsuya K; Yamasaki Y; Akiyama K; Li H; Yamamoto T; Saito Y; Nakamura M
    Mol Cell Biol; 2004 Sep; 24(17):7456-68. PubMed ID: 15314156
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation.
    Kondo A; Hirayama N; Sugito Y; Shono M; Tanaka T; Kitamura N
    J Biol Chem; 2008 Jan; 283(3):1428-1436. PubMed ID: 18003605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Negative action of hepatocyte growth factor/c-Met system on angiotensin II signaling via ligand-dependent epithelial growth factor receptor degradation mechanism in vascular smooth muscle cells.
    Sanada F; Taniyama Y; Iekushi K; Azuma J; Okayama K; Kusunoki H; Koibuchi N; Doi T; Aizawa Y; Morishita R
    Circ Res; 2009 Sep; 105(7):667-75, 13 p following 675. PubMed ID: 19713535
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling.
    Gual P; Giordano S; Anguissola S; Parker PJ; Comoglio PM
    Oncogene; 2001 Jan; 20(2):156-66. PubMed ID: 11313945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy.
    Li Y; Lal B; Kwon S; Fan X; Saldanha U; Reznik TE; Kuchner EB; Eberhart C; Laterra J; Abounader R
    Cancer Res; 2005 Oct; 65(20):9355-62. PubMed ID: 16230398
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis.
    Gual P; Giordano S; Williams TA; Rocchi S; Van Obberghen E; Comoglio PM
    Oncogene; 2000 Mar; 19(12):1509-18. PubMed ID: 10734310
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Met receptor tyrosine kinase: enhanced signaling through adapter proteins.
    Furge KA; Zhang YW; Vande Woude GF
    Oncogene; 2000 Nov; 19(49):5582-9. PubMed ID: 11114738
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation.
    Garcia-Guzman M; Dolfi F; Zeh K; Vuori K
    Oncogene; 1999 Dec; 18(54):7775-86. PubMed ID: 10618718
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endosomal dynamics of Met determine signaling output.
    Hammond DE; Carter S; McCullough J; Urbé S; Vande Woude G; Clague MJ
    Mol Biol Cell; 2003 Apr; 14(4):1346-54. PubMed ID: 12686592
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.