457 related articles for article (PubMed ID: 21784859)
41. Rag GTPase in amino acid signaling.
Kim J; Kim E
Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
[TBL] [Abstract][Full Text] [Related]
42. Tumor suppressors TSC1 and TSC2 differentially modulate actin cytoskeleton and motility of mouse embryonic fibroblasts.
Goncharova EA; James ML; Kudryashova TV; Goncharov DA; Krymskaya VP
PLoS One; 2014; 9(10):e111476. PubMed ID: 25360538
[TBL] [Abstract][Full Text] [Related]
43. TSC1 controls distribution of actin fibers through its effect on function of Rho family of small GTPases and regulates cell migration and polarity.
Ohsawa M; Kobayashi T; Okura H; Igarashi T; Mizuguchi M; Hino O
PLoS One; 2013; 8(1):e54503. PubMed ID: 23355874
[TBL] [Abstract][Full Text] [Related]
44. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Inoki K; Li Y; Xu T; Guan KL
Genes Dev; 2003 Aug; 17(15):1829-34. PubMed ID: 12869586
[TBL] [Abstract][Full Text] [Related]
45. Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.
Demetriades C; Doumpas N; Teleman AA
Cell; 2014 Feb; 156(4):786-99. PubMed ID: 24529380
[TBL] [Abstract][Full Text] [Related]
46. Rheb and Rags come together at the lysosome to activate mTORC1.
Groenewoud MJ; Zwartkruis FJ
Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162
[TBL] [Abstract][Full Text] [Related]
47. CBAP regulates the function of Akt-associated TSC protein complexes to modulate mTORC1 signaling.
Liao WT; Chiang YJ; Yang-Yen HF; Hsu LC; Chang ZF; Yen JJY
J Biol Chem; 2023 Dec; 299(12):105455. PubMed ID: 37949232
[TBL] [Abstract][Full Text] [Related]
48. The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner.
Patursky-Polischuk I; Stolovich-Rain M; Hausner-Hanochi M; Kasir J; Cybulski N; Avruch J; Rüegg MA; Hall MN; Meyuhas O
Mol Cell Biol; 2009 Feb; 29(3):640-9. PubMed ID: 19047368
[TBL] [Abstract][Full Text] [Related]
49. Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like cells.
Lee PS; Tsang SW; Moses MA; Trayes-Gibson Z; Hsiao LL; Jensen R; Squillace R; Kwiatkowski DJ
Am J Respir Cell Mol Biol; 2010 Feb; 42(2):227-34. PubMed ID: 19395678
[TBL] [Abstract][Full Text] [Related]
50. Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment.
Angarola B; Ferguson SM
Mol Biol Cell; 2019 Oct; 30(22):2750-2760. PubMed ID: 31532697
[TBL] [Abstract][Full Text] [Related]
51. Point mutations of the mTOR-RHEB pathway in renal cell carcinoma.
Ghosh AP; Marshall CB; Coric T; Shim EH; Kirkman R; Ballestas ME; Ikura M; Bjornsti MA; Sudarshan S
Oncotarget; 2015 Jul; 6(20):17895-910. PubMed ID: 26255626
[TBL] [Abstract][Full Text] [Related]
52. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M; Cash T; Cheung M; Robertson GP; Astrinidis A; Henske EP
J Biol Chem; 2004 Jul; 279(29):29930-7. PubMed ID: 15150271
[TBL] [Abstract][Full Text] [Related]
53. Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
Menon S; Dibble CC; Talbott G; Hoxhaj G; Valvezan AJ; Takahashi H; Cantley LC; Manning BD
Cell; 2014 Feb; 156(4):771-85. PubMed ID: 24529379
[TBL] [Abstract][Full Text] [Related]
54. Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
Mazhab-Jafari MT; Marshall CB; Ho J; Ishiyama N; Stambolic V; Ikura M
J Biol Chem; 2014 May; 289(18):12195-201. PubMed ID: 24648513
[TBL] [Abstract][Full Text] [Related]
55. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1).
Shibutani S; Okazaki H; Iwata H
J Biol Chem; 2017 Nov; 292(44):18052-18061. PubMed ID: 28808055
[TBL] [Abstract][Full Text] [Related]
56. Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Malhowski AJ; Hira H; Bashiruddin S; Warburton R; Goto J; Robert B; Kwiatkowski DJ; Finlay GA
Hum Mol Genet; 2011 Apr; 20(7):1290-305. PubMed ID: 21212099
[TBL] [Abstract][Full Text] [Related]
57. Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis.
Lacher MD; Pincheira R; Zhu Z; Camoretti-Mercado B; Matli M; Warren RS; Castro AF
Oncogene; 2010 Dec; 29(50):6543-56. PubMed ID: 20818424
[TBL] [Abstract][Full Text] [Related]
58. Spatial regulation of the mTORC1 system in amino acids sensing pathway.
Suzuki T; Inoki K
Acta Biochim Biophys Sin (Shanghai); 2011 Sep; 43(9):671-9. PubMed ID: 21785113
[TBL] [Abstract][Full Text] [Related]
59. mTORC2 is required for proliferation and survival of TSC2-null cells.
Goncharova EA; Goncharov DA; Li H; Pimtong W; Lu S; Khavin I; Krymskaya VP
Mol Cell Biol; 2011 Jun; 31(12):2484-98. PubMed ID: 21482669
[TBL] [Abstract][Full Text] [Related]
60. Amino acid signalling upstream of mTOR.
Jewell JL; Russell RC; Guan KL
Nat Rev Mol Cell Biol; 2013 Mar; 14(3):133-9. PubMed ID: 23361334
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]