BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 21787315)

  • 1. Mitochondrial β-amyloid in Alzheimer's disease.
    Borger E; Aitken L; Muirhead KE; Allen ZE; Ainge JA; Conway SJ; Gunn-Moore FJ
    Biochem Soc Trans; 2011 Aug; 39(4):868-73. PubMed ID: 21787315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Mitochondrial enzyme ABAD and its role in the development and treatment of Alzheimer's disease].
    Benek O; Musílek K; Kuca K
    Ceska Slov Farm; 2012 Aug; 61(4):144-9. PubMed ID: 23251955
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitochondrial Abeta: a potential cause of metabolic dysfunction in Alzheimer's disease.
    Chen X; Yan SD
    IUBMB Life; 2006 Dec; 58(12):686-94. PubMed ID: 17424907
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction.
    Takuma K; Yao J; Huang J; Xu H; Chen X; Luddy J; Trillat AC; Stern DM; Arancio O; Yan SS
    FASEB J; 2005 Apr; 19(6):597-8. PubMed ID: 15665036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.
    Yao J; Du H; Yan S; Fang F; Wang C; Lue LF; Guo L; Chen D; Stern DM; Gunn Moore FJ; Xi Chen J; Arancio O; Yan SS
    J Neurosci; 2011 Feb; 31(6):2313-20. PubMed ID: 21307267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
    Lustbader JW; Cirilli M; Lin C; Xu HW; Takuma K; Wang N; Caspersen C; Chen X; Pollak S; Chaney M; Trinchese F; Liu S; Gunn-Moore F; Lue LF; Walker DG; Kuppusamy P; Zewier ZL; Arancio O; Stern D; Yan SS; Wu H
    Science; 2004 Apr; 304(5669):448-52. PubMed ID: 15087549
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathogenic role of mitochondrial [correction of mitochondral] amyloid-beta peptide.
    Chen JX; Yan SD
    Expert Rev Neurother; 2007 Nov; 7(11):1517-25. PubMed ID: 17997700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The consequences of mitochondrial amyloid beta-peptide in Alzheimer's disease.
    Muirhead KE; Borger E; Aitken L; Conway SJ; Gunn-Moore FJ
    Biochem J; 2010 Feb; 426(3):255-70. PubMed ID: 20175748
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aβ in a Neuroinflammatory Alzheimer's Disease Mouse Model.
    Zakaria A; Hamdi N; Abdel-Kader RM
    Mol Neurobiol; 2016 Mar; 53(2):1220-1228. PubMed ID: 25601181
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer's Disease.
    Morsy A; Trippier PC
    J Med Chem; 2019 May; 62(9):4252-4264. PubMed ID: 30444369
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of mitochondrial amyloid-beta in Alzheimer's disease.
    Chen JX; Yan SS
    J Alzheimers Dis; 2010; 20 Suppl 2():S569-78. PubMed ID: 20463403
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Behavioral stress causes mitochondrial dysfunction via ABAD up-regulation and aggravates plaque pathology in the brain of a mouse model of Alzheimer disease.
    Seo JS; Lee KW; Kim TK; Baek IS; Im JY; Han PL
    Free Radic Biol Med; 2011 Jun; 50(11):1526-35. PubMed ID: 21382475
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice.
    Dragicevic N; Mamcarz M; Zhu Y; Buzzeo R; Tan J; Arendash GW; Bradshaw PC
    J Alzheimers Dis; 2010; 20 Suppl 2():S535-50. PubMed ID: 20463404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functionalized Allopurinols Targeting Amyloid-Binding Alcohol Dehydrogenase Rescue Aβ-Induced Mitochondrial Dysfunction.
    Morsy A; Maddeboina K; Gao J; Wang H; Valdez J; Dow LF; Wang X; Trippier PC
    ACS Chem Neurosci; 2022 Jul; 13(14):2176-2190. PubMed ID: 35802826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ABAD: a potential therapeutic target for Abeta-induced mitochondrial dysfunction in Alzheimer's disease.
    Marques AT; Fernandes PA; Ramos MJ
    Mini Rev Med Chem; 2009 Jul; 9(8):1002-8. PubMed ID: 19601895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol.
    Lim YA; Grimm A; Giese M; Mensah-Nyagan AG; Villafranca JE; Ittner LM; Eckert A; Götz J
    PLoS One; 2011; 6(12):e28887. PubMed ID: 22174920
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ABAD/17β-HSD10 reduction contributes to the protective mechanism of huperzine a on the cerebral mitochondrial function in APP/PS1 mice.
    Xiao X; Chen Q; Zhu X; Wang Y
    Neurobiol Aging; 2019 Sep; 81():77-87. PubMed ID: 31252207
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?
    Borger E; Aitken L; Du H; Zhang W; Gunn-Moore FJ; Yan SS
    Curr Alzheimer Res; 2013 Jan; 10(1):21-9. PubMed ID: 22742981
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of small-molecule inhibitors of the Abeta-ABAD interaction.
    Xie Y; Deng S; Chen Z; Yan S; Landry DW
    Bioorg Med Chem Lett; 2006 Sep; 16(17):4657-60. PubMed ID: 16781151
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytoprotective role of mitochondrial amyloid beta peptide-binding alcohol dehydrogenase against a cytotoxic aldehyde.
    Murakami Y; Ohsawa I; Kasahara T; Ohta S
    Neurobiol Aging; 2009 Feb; 30(2):325-9. PubMed ID: 17707551
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.