201 related articles for article (PubMed ID: 21787760)
1. Understanding SOS (Son of Sevenless).
Pierre S; Bats AS; Coumoul X
Biochem Pharmacol; 2011 Nov; 82(9):1049-56. PubMed ID: 21787760
[TBL] [Abstract][Full Text] [Related]
2. Structural analysis of autoinhibition in the Ras activator Son of sevenless.
Sondermann H; Soisson SM; Boykevisch S; Yang SS; Bar-Sagi D; Kuriyan J
Cell; 2004 Oct; 119(3):393-405. PubMed ID: 15507210
[TBL] [Abstract][Full Text] [Related]
3. Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation.
Pierre S; Bats AS; Chevallier A; Bui LC; Ambolet-Camoit A; Garlatti M; Aggerbeck M; Barouki R; Coumoul X
Biochem Pharmacol; 2011 Jan; 81(2):304-13. PubMed ID: 20950586
[TBL] [Abstract][Full Text] [Related]
4. Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos.
Zhao C; Du G; Skowronek K; Frohman MA; Bar-Sagi D
Nat Cell Biol; 2007 Jun; 9(6):706-12. PubMed ID: 17486115
[TBL] [Abstract][Full Text] [Related]
5. Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.
Webb GC; Jenkins NA; Largaespada DA; Copeland NG; Fernandez CS; Bowtell DD
Genomics; 1993 Oct; 18(1):14-9. PubMed ID: 8276400
[TBL] [Abstract][Full Text] [Related]
6. The two hats of SOS.
Nimnual A; Bar-Sagi D
Sci STKE; 2002 Aug; 2002(145):pe36. PubMed ID: 12177507
[TBL] [Abstract][Full Text] [Related]
7. Germline gain-of-function mutations in SOS1 cause Noonan syndrome.
Roberts AE; Araki T; Swanson KD; Montgomery KT; Schiripo TA; Joshi VA; Li L; Yassin Y; Tamburino AM; Neel BG; Kucherlapati RS
Nat Genet; 2007 Jan; 39(1):70-4. PubMed ID: 17143285
[TBL] [Abstract][Full Text] [Related]
8. Activation of Ras and its downstream extracellular signal-regulated protein kinases by the CDC25 homology domain of mouse Son-of-sevenless 1 (mSos1).
Kim JH; Shirouzu M; Kataoka T; Bowtell D; Yokoyama S
Oncogene; 1998 May; 16(20):2597-607. PubMed ID: 9632136
[TBL] [Abstract][Full Text] [Related]
9. Guanine nucleotide exchange factors: activators of Ras superfamily proteins.
Overbeck AF; Brtva TR; Cox AD; Graham SM; Huff SY; Khosravi-Far R; Quilliam LA; Solski PA; Der CJ
Mol Reprod Dev; 1995 Dec; 42(4):468-76. PubMed ID: 8607978
[TBL] [Abstract][Full Text] [Related]
10. SOS1 over-expression in genital skin fibroblasts from hirsute women: a putative role of the SOS1/RAS pathway in the pathogenesis of hirsutism.
Minella D; Wannenes F; Biancolella M; Amati F; Testa B; Nardone A; Bueno S; Fabbri A; Lauro D; Novelli G; Moretti C
J Biol Regul Homeost Agents; 2011; 25(4):615-26. PubMed ID: 22217993
[TBL] [Abstract][Full Text] [Related]
11. A Ras-induced conformational switch in the Ras activator Son of sevenless.
Freedman TS; Sondermann H; Friedland GD; Kortemme T; Bar-Sagi D; Marqusee S; Kuriyan J
Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16692-7. PubMed ID: 17075039
[TBL] [Abstract][Full Text] [Related]
12. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
Gureasko J; Kuchment O; Makino DL; Sondermann H; Bar-Sagi D; Kuriyan J
Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3430-5. PubMed ID: 20133692
[TBL] [Abstract][Full Text] [Related]
13. Sos1 regulates sustained TCR-mediated Erk activation.
Poltorak M; Meinert I; Stone JC; Schraven B; Simeoni L
Eur J Immunol; 2014 May; 44(5):1535-40. PubMed ID: 24497027
[TBL] [Abstract][Full Text] [Related]
14. Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.
Oh-hora M; Johmura S; Hashimoto A; Hikida M; Kurosaki T
J Exp Med; 2003 Dec; 198(12):1841-51. PubMed ID: 14676298
[TBL] [Abstract][Full Text] [Related]
15. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
Hu Y; Bowtell DD
Oncogene; 1996 May; 12(9):1865-72. PubMed ID: 8649846
[TBL] [Abstract][Full Text] [Related]
16. Targeting Son of Sevenless 1: The pacemaker of KRAS.
Kessler D; Gerlach D; Kraut N; McConnell DB
Curr Opin Chem Biol; 2021 Jun; 62():109-118. PubMed ID: 33848766
[TBL] [Abstract][Full Text] [Related]
17. New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.
Silver SJ; Chen F; Doyon L; Zink AW; Rebay I
Genesis; 2004 Aug; 39(4):263-72. PubMed ID: 15286999
[TBL] [Abstract][Full Text] [Related]
18. Significance of the Grb2 and son of sevenless (Sos) proteins in human bladder cancer cell lines.
Watanabe T; Shinohara N; Moriya K; Sazawa A; Kobayashi Y; Ogiso Y; Takiguchi M; Yasuda J; Koyanagi T; Kuzumaki N; Hashimoto A
IUBMB Life; 2000 Apr; 49(4):317-20. PubMed ID: 10995035
[TBL] [Abstract][Full Text] [Related]
19. The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties.
Qian X; Esteban L; Vass WC; Upadhyaya C; Papageorge AG; Yienger K; Ward JM; Lowy DR; Santos E
EMBO J; 2000 Feb; 19(4):642-54. PubMed ID: 10675333
[TBL] [Abstract][Full Text] [Related]
20. High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling.
Burns MC; Howes JE; Sun Q; Little AJ; Camper DV; Abbott JR; Phan J; Lee T; Waterson AG; Rossanese OW; Fesik SW
Anal Biochem; 2018 May; 548():44-52. PubMed ID: 29444450
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]