BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 21787891)

  • 1. A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C).
    Grunert T; Leitner NR; Marchetti-Deschmann M; Miller I; Wallner B; Radwan M; Vogl C; Kolbe T; Kratky D; Gemeiner M; Allmaier G; Müller M; Strobl B
    J Proteomics; 2011 Nov; 74(12):2866-80. PubMed ID: 21787891
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes.
    Vogl C; Flatt T; Fuhrmann B; Hofmann E; Wallner B; Stiefvater R; Kovarik P; Strobl B; Müller M
    BMC Genomics; 2010 Mar; 11():199. PubMed ID: 20338026
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS).
    Radwan M; Miller I; Grunert T; Marchetti-Deschmann M; Vogl C; O'Donoghue N; Dunn MJ; Kolbe T; Allmaier G; Gemeiner M; Müller M; Strobl B
    Proteomics; 2008 Sep; 8(17):3469-85. PubMed ID: 18683816
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity.
    Strobl B; Stoiber D; Sexl V; Mueller M
    Front Biosci (Landmark Ed); 2011 Jun; 16(9):3214-32. PubMed ID: 21622231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TYK2 kinase activity is required for functional type I interferon responses in vivo.
    Prchal-Murphy M; Semper C; Lassnig C; Wallner B; Gausterer C; Teppner-Klymiuk I; Kobolak J; Müller S; Kolbe T; Karaghiosoff M; Dinnyés A; Rülicke T; Leitner NR; Strobl B; Müller M
    PLoS One; 2012; 7(6):e39141. PubMed ID: 22723949
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27.
    Bosmann M; Strobl B; Kichler N; Rigler D; Grailer JJ; Pache F; Murray PJ; Müller M; Ward PA
    J Leukoc Biol; 2014 Jul; 96(1):123-31. PubMed ID: 24604832
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Atlantic salmon protein tyrosine kinase Tyk2: molecular cloning, modulation of expression and function.
    Sobhkhez M; Hansen T; Iliev DB; Skjesol A; Jørgensen JB
    Dev Comp Immunol; 2013 Dec; 41(4):553-63. PubMed ID: 23872231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tyk2-dependent bystander activation of conventional and nonconventional Th1 cell subsets contributes to innate host defense against Listeria monocytogenes infection.
    Hashiguchi T; Oyamada A; Sakuraba K; Shimoda K; Nakayama KI; Iwamoto Y; Yoshikai Y; Yamada H
    J Immunol; 2014 May; 192(10):4739-47. PubMed ID: 24729620
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells.
    Nakamura R; Shibata K; Yamada H; Shimoda K; Nakayama K; Yoshikai Y
    J Immunol; 2008 Aug; 181(3):2071-5. PubMed ID: 18641345
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus.
    Strobl B; Bubic I; Bruns U; Steinborn R; Lajko R; Kolbe T; Karaghiosoff M; Kalinke U; Jonjic S; Müller M
    J Immunol; 2005 Sep; 175(6):4000-8. PubMed ID: 16148148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5.
    De Miranda J; Yaddanapudi K; Hornig M; Lipkin WI
    FASEB J; 2009 Apr; 23(4):1064-71. PubMed ID: 19036857
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The JAK and STAT family members of the mandarin fish Siniperca chuatsi: molecular cloning, tissues distribution and immunobiological activity.
    Guo CJ; Zhang YF; Yang LS; Yang XB; Wu YY; Liu D; Chen WJ; Weng SP; Yu XQ; He JG
    Fish Shellfish Immunol; 2009 Aug; 27(2):349-59. PubMed ID: 19539032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells.
    Tai Z; Lin Y; He Y; Huang J; Guo J; Yang L; Zhang G; Wang F
    Cell Signal; 2014 Mar; 26(3):619-28. PubMed ID: 24333668
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).
    Min X; Ungureanu D; Maxwell S; Hammarén H; Thibault S; Hillert EK; Ayres M; Greenfield B; Eksterowicz J; Gabel C; Walker N; Silvennoinen O; Wang Z
    J Biol Chem; 2015 Nov; 290(45):27261-27270. PubMed ID: 26359499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Statins attenuate antiviral IFN-β and ISG expression via inhibition of IRF3 and JAK/STAT signaling in poly(I:C)-treated hyperlipidemic mice and macrophages.
    Koike A; Tsujinaka K; Fujimori K
    FEBS J; 2021 Jul; 288(14):4249-4266. PubMed ID: 33452755
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.
    Ishizaki M; Muromoto R; Akimoto T; Ohshiro Y; Takahashi M; Sekine Y; Maeda H; Shimoda K; Oritani K; Matsuda T
    Int Immunol; 2011 Sep; 23(9):575-82. PubMed ID: 21765170
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells.
    Marroqui L; Dos Santos RS; Fløyel T; Grieco FA; Santin I; Op de Beeck A; Marselli L; Marchetti P; Pociot F; Eizirik DL
    Diabetes; 2015 Nov; 64(11):3808-17. PubMed ID: 26239055
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyrosine kinase 2 - Surveillant of tumours and bona fide oncogene.
    Leitner NR; Witalisz-Siepracka A; Strobl B; Müller M
    Cytokine; 2017 Jan; 89():209-218. PubMed ID: 26631911
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2.
    Piganis RA; De Weerd NA; Gould JA; Schindler CW; Mansell A; Nicholson SE; Hertzog PJ
    J Biol Chem; 2011 Sep; 286(39):33811-8. PubMed ID: 21757742
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression patterns of three JAK-STAT pathway genes in feather follicle development during chicken embryogenesis.
    Tao Y; Zhou X; Liu Z; Zhang X; Nie Y; Zheng X; Li S; Hu X; Yang G; Zhao Q; Mou C
    Gene Expr Patterns; 2020 Jan; 35():119078. PubMed ID: 31759166
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.