These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 21788423)

  • 1. Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide.
    Theile JW; Cummins TR
    Mol Pharmacol; 2011 Oct; 80(4):724-34. PubMed ID: 21788423
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.
    Eberhardt M; Nakajima J; Klinger AB; Neacsu C; Hühne K; O'Reilly AO; Kist AM; Lampe AK; Fischer K; Gibson J; Nau C; Winterpacht A; Lampert A
    J Biol Chem; 2014 Jan; 289(4):1971-80. PubMed ID: 24311784
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.
    Patel RR; Barbosa C; Brustovetsky T; Brustovetsky N; Cummins TR
    Brain; 2016 Aug; 139(Pt 8):2164-81. PubMed ID: 27267376
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navbeta4 peptide-mediated resurgent sodium currents.
    Theile JW; Jarecki BW; Piekarz AD; Cummins TR
    J Physiol; 2011 Feb; 589(Pt 3):597-608. PubMed ID: 21115638
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sodium channel slow inactivation interferes with open channel block.
    Hampl M; Eberhardt E; O'Reilly AO; Lampert A
    Sci Rep; 2016 May; 6():25974. PubMed ID: 27174182
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.
    Patel RR; Barbosa C; Xiao Y; Cummins TR
    PLoS One; 2015; 10(7):e0133485. PubMed ID: 26182346
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.
    Jarecki BW; Piekarz AD; Jackson JO; Cummins TR
    J Clin Invest; 2010 Jan; 120(1):369-78. PubMed ID: 20038812
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons.
    Klinger AB; Eberhardt M; Link AS; Namer B; Kutsche LK; Schuy ET; Sittl R; Hoffmann T; Alzheimer C; Huth T; Carr RW; Lampert A
    Mol Pain; 2012 Sep; 8():69. PubMed ID: 22978421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased Resurgent Sodium Currents in Nav1.8 Contribute to Nociceptive Sensory Neuron Hyperexcitability Associated with Peripheral Neuropathies.
    Xiao Y; Barbosa C; Pei Z; Xie W; Strong JA; Zhang JM; Cummins TR
    J Neurosci; 2019 Feb; 39(8):1539-1550. PubMed ID: 30617209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli.
    Yang Y; Huang J; Mis MA; Estacion M; Macala L; Shah P; Schulman BR; Horton DB; Dib-Hajj SD; Waxman SG
    J Neurosci; 2016 Jul; 36(28):7511-22. PubMed ID: 27413160
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes.
    Okura D; Horishita T; Ueno S; Yanagihara N; Sudo Y; Uezono Y; Sata T
    Anesth Analg; 2014 Mar; 118(3):554-62. PubMed ID: 24557103
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions among DIV voltage-sensor movement, fast inactivation, and resurgent Na current induced by the NaVβ4 open-channel blocking peptide.
    Lewis AH; Raman IM
    J Gen Physiol; 2013 Sep; 142(3):191-206. PubMed ID: 23940261
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons.
    Barbosa C; Tan ZY; Wang R; Xie W; Strong JA; Patel RR; Vasko MR; Zhang JM; Cummins TR
    Mol Pain; 2015 Sep; 11():60. PubMed ID: 26408173
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders.
    Estacion M; Dib-Hajj SD; Benke PJ; Te Morsche RH; Eastman EM; Macala LJ; Drenth JP; Waxman SG
    J Neurosci; 2008 Oct; 28(43):11079-88. PubMed ID: 18945915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders.
    Cheng X; Dib-Hajj SD; Tyrrell L; Wright DA; Fischer TZ; Waxman SG
    Mol Pain; 2010 Apr; 6():24. PubMed ID: 20429905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Upregulation of the sodium channel NaVβ4 subunit and its contributions to mechanical hypersensitivity and neuronal hyperexcitability in a rat model of radicular pain induced by local dorsal root ganglion inflammation.
    Xie W; Tan ZY; Barbosa C; Strong JA; Cummins TR; Zhang JM
    Pain; 2016 Apr; 157(4):879-891. PubMed ID: 26785322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin.
    Grieco TM; Raman IM
    J Neurosci; 2004 Jan; 24(1):35-42. PubMed ID: 14715935
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons.
    Barbosa C; Xiao Y; Johnson AJ; Xie W; Strong JA; Zhang JM; Cummins TR
    Pflugers Arch; 2017 Feb; 469(2):195-212. PubMed ID: 27999940
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable.
    Dib-Hajj SD; Estacion M; Jarecki BW; Tyrrell L; Fischer TZ; Lawden M; Cummins TR; Waxman SG
    Mol Pain; 2008 Sep; 4():37. PubMed ID: 18803825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity.
    Sheets PL; Jackson JO; Waxman SG; Dib-Hajj SD; Cummins TR
    J Physiol; 2007 Jun; 581(Pt 3):1019-31. PubMed ID: 17430993
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.