BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 21789034)

  • 1. Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity.
    Cole DJ; Rajendra E; Roberts-Thomson M; Hardwick B; McKenzie GJ; Payne MC; Venkitaraman AR; Skylaris CK
    PLoS Comput Biol; 2011 Jul; 7(7):e1002096. PubMed ID: 21789034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase.
    Rajendra E; Venkitaraman AR
    Nucleic Acids Res; 2010 Jan; 38(1):82-96. PubMed ID: 19875419
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BRCA2 regulates DMC1-mediated recombination through the BRC repeats.
    Martinez JS; von Nicolai C; Kim T; Ehlén Å; Mazin AV; Kowalczykowski SC; Carreira A
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3515-20. PubMed ID: 26976601
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Divergent binding mode for a protozoan BRC repeat to RAD51.
    Pantelejevs T; Hyvönen M
    Biochem J; 2022 May; 479(10):1031-1043. PubMed ID: 35502837
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A mitotic function for the high-mobility group protein HMG20b regulated by its interaction with the BRC repeats of the BRCA2 tumor suppressor.
    Lee M; Daniels MJ; Garnett MJ; Venkitaraman AR
    Oncogene; 2011 Jul; 30(30):3360-9. PubMed ID: 21399666
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer.
    Lo T; Pellegrini L; Venkitaraman AR; Blundell TL
    DNA Repair (Amst); 2003 Sep; 2(9):1015-28. PubMed ID: 12967658
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity.
    Chatterjee G; Jimenez-Sainz J; Presti T; Nguyen T; Jensen RB
    Nucleic Acids Res; 2016 Jun; 44(11):5256-70. PubMed ID: 27084934
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51.
    Carreira A; Hilario J; Amitani I; Baskin RJ; Shivji MK; Venkitaraman AR; Kowalczykowski SC
    Cell; 2009 Mar; 136(6):1032-43. PubMed ID: 19303847
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRCA2 BRC motifs bind RAD51-DNA filaments.
    Galkin VE; Esashi F; Yu X; Yang S; West SC; Egelman EH
    Proc Natl Acad Sci U S A; 2005 Jun; 102(24):8537-42. PubMed ID: 15937124
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A variant of the breast cancer type 2 susceptibility protein (BRC) repeat is essential for the RECQL5 helicase to interact with RAD51 recombinase for genome stabilization.
    Islam MN; Paquet N; Fox D; Dray E; Zheng XF; Klein H; Sung P; Wang W
    J Biol Chem; 2012 Jul; 287(28):23808-18. PubMed ID: 22645136
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.
    Pellegrini L; Yu DS; Lo T; Anand S; Lee M; Blundell TL; Venkitaraman AR
    Nature; 2002 Nov; 420(6913):287-93. PubMed ID: 12442171
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51.
    Tal A; Arbel-Goren R; Stavans J
    J Mol Biol; 2009 Nov; 393(5):1007-12. PubMed ID: 19747923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange.
    Shivji MK; Davies OR; Savill JM; Bates DL; Pellegrini L; Venkitaraman AR
    Nucleic Acids Res; 2006; 34(14):4000-11. PubMed ID: 16914443
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms.
    Carreira A; Kowalczykowski SC
    Proc Natl Acad Sci U S A; 2011 Jun; 108(26):10448-53. PubMed ID: 21670257
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
    Short JM; Liu Y; Chen S; Soni N; Madhusudhan MS; Shivji MK; Venkitaraman AR
    Nucleic Acids Res; 2016 Nov; 44(19):9017-9030. PubMed ID: 27596592
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange.
    Shivji MK; Mukund SR; Rajendra E; Chen S; Short JM; Savill J; Klenerman D; Venkitaraman AR
    Proc Natl Acad Sci U S A; 2009 Aug; 106(32):13254-9. PubMed ID: 19628690
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and interaction of BRC4 analogous peptides with RAD51(241-260).
    Li J; Lu K; Lv M; Liu G; Ma L; Qi J
    Amino Acids; 2020 Mar; 52(3):361-369. PubMed ID: 31875260
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction between Arabidopsis Brca2 and its partners Rad51, Dmc1, and Dss1.
    Dray E; Siaud N; Dubois E; Doutriaux MP
    Plant Physiol; 2006 Mar; 140(3):1059-69. PubMed ID: 16415210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trypanosoma brucei BRCA2 acts in a life cycle-specific genome stability process and dictates BRC repeat number-dependent RAD51 subnuclear dynamics.
    Trenaman A; Hartley C; Prorocic M; Passos-Silva DG; van den Hoek M; Nechyporuk-Zloy V; Machado CR; McCulloch R
    Nucleic Acids Res; 2013 Jan; 41(2):943-60. PubMed ID: 23222131
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and characterization of BRC4 mutants based on the crystal structure of BRC4-RAD51(191-220).
    Zhao D; Lu K
    J Mol Model; 2015 Nov; 21(11):299. PubMed ID: 26522863
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.