BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

409 related articles for article (PubMed ID: 21789225)

  • 1. Functional diversity of human basic helix-loop-helix transcription factor TCF4 isoforms generated by alternative 5' exon usage and splicing.
    Sepp M; Kannike K; Eesmaa A; Urb M; Timmusk T
    PLoS One; 2011; 6(7):e22138. PubMed ID: 21789225
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pitt-Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects.
    Sepp M; Pruunsild P; Timmusk T
    Hum Mol Genet; 2012 Jul; 21(13):2873-88. PubMed ID: 22460224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acetylation of human TCF4 (TCF7L2) proteins attenuates inhibition by the HBP1 repressor and induces a conformational change in the TCF4::DNA complex.
    Elfert S; Weise A; Bruser K; Biniossek ML; Jägle S; Senghaas N; Hecht A
    PLoS One; 2013; 8(4):e61867. PubMed ID: 23613959
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TCF4 (e2-2; ITF2): a schizophrenia-associated gene with pleiotropic effects on human disease.
    Navarrete K; Pedroso I; De Jong S; Stefansson H; Steinberg S; Stefansson K; Ophoff RA; Schalkwyk LC; Collier DA
    Am J Med Genet B Neuropsychiatr Genet; 2013 Jan; 162B(1):1-16. PubMed ID: 23129290
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Complex translocation disrupting TCF4 and altering TCF4 isoform expression segregates as mild autosomal dominant intellectual disability.
    Maduro V; Pusey BN; Cherukuri PF; Atkins P; du Souich C; Rupps R; Limbos M; Adams DR; Bhatt SS; Eydoux P; Links AE; Lehman A; Malicdan MC; Mason CE; Morimoto M; Mullikin JC; Sear A; Van Karnebeek C; Stankiewicz P; Gahl WA; Toro C; Boerkoel CF
    Orphanet J Rare Dis; 2016 May; 11(1):62. PubMed ID: 27179618
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional analysis of TCF4 missense mutations that cause Pitt-Hopkins syndrome.
    Forrest M; Chapman RM; Doyle AM; Tinsley CL; Waite A; Blake DJ
    Hum Mutat; 2012 Dec; 33(12):1676-86. PubMed ID: 22777675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective.
    Quednow BB; Brzózka MM; Rossner MJ
    Cell Mol Life Sci; 2014 Aug; 71(15):2815-35. PubMed ID: 24413739
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Partial deletion of TCF4 in three generation family with non-syndromic intellectual disability, without features of Pitt-Hopkins syndrome.
    Kharbanda M; Kannike K; Lampe A; Berg J; Timmusk T; Sepp M
    Eur J Med Genet; 2016 Jun; 59(6-7):310-4. PubMed ID: 27132474
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ITF2 prevents activation of the β-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.
    Shin HW; Choi H; So D; Kim YI; Cho K; Chung HJ; Lee KH; Chun YS; Cho CH; Kang GH; Kim WH; Park JW
    Gastroenterology; 2014 Aug; 147(2):430-442.e8. PubMed ID: 24846398
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The emerging roles of TCF4 in disease and development.
    Forrest MP; Hill MJ; Quantock AJ; Martin-Rendon E; Blake DJ
    Trends Mol Med; 2014 Jun; 20(6):322-31. PubMed ID: 24594265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impairment of different protein domains causes variable clinical presentation within Pitt-Hopkins syndrome and suggests intragenic molecular syndromology of TCF4.
    Bedeschi MF; Marangi G; Calvello MR; Ricciardi S; Leone FPC; Baccarin M; Guerneri S; Orteschi D; Murdolo M; Lattante S; Frangella S; Keena B; Harr MH; Zackai E; Zollino M
    Eur J Med Genet; 2017 Nov; 60(11):565-571. PubMed ID: 28807867
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The subcellular localization of bHLH transcription factor TCF4 is mediated by multiple nuclear localization and nuclear export signals.
    Greb-Markiewicz B; Kazana W; Zarębski M; Ożyhar A
    Sci Rep; 2019 Oct; 9(1):15629. PubMed ID: 31666615
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A.
    Sepp M; Vihma H; Nurm K; Urb M; Page SC; Roots K; Hark A; Maher BJ; Pruunsild P; Timmusk T
    J Neurosci; 2017 Oct; 37(43):10516-10527. PubMed ID: 28951451
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domains.
    Kuiper RP; Schepens M; Thijssen J; Schoenmakers EF; van Kessel AG
    Nucleic Acids Res; 2004; 32(8):2315-22. PubMed ID: 15118077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas.
    Bleckmann A; Siam L; Klemm F; Rietkötter E; Wegner C; Kramer F; Beissbarth T; Binder C; Stadelmann C; Pukrop T
    Clin Exp Metastasis; 2013 Apr; 30(4):471-82. PubMed ID: 23224985
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A big gene linked to small eyes encodes multiple Mitf isoforms: many promoters make light work.
    Yasumoto K; Amae S; Udono T; Fuse N; Takeda K; Shibahara S
    Pigment Cell Res; 1998 Dec; 11(6):329-36. PubMed ID: 9870544
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conservation and expression of an alternative 3' exon of Runx2 encoding a novel proline-rich C-terminal domain.
    Terry A; Kilbey A; Vaillant F; Stewart M; Jenkins A; Cameron E; Neil JC
    Gene; 2004 Jul; 336(1):115-25. PubMed ID: 15225881
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genotype-phenotype analysis of TCF4 mutations causing Pitt-Hopkins syndrome shows increased seizure activity with missense mutations.
    Rosenfeld JA; Leppig K; Ballif BC; Thiese H; Erdie-Lalena C; Bawle E; Sastry S; Spence JE; Bandholz A; Surti U; Zonana J; Keller K; Meschino W; Bejjani BA; Torchia BS; Shaffer LG
    Genet Med; 2009 Nov; 11(11):797-805. PubMed ID: 19938247
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TCF4, schizophrenia, and Pitt-Hopkins Syndrome.
    Blake DJ; Forrest M; Chapman RM; Tinsley CL; O'Donovan MC; Owen MJ
    Schizophr Bull; 2010 May; 36(3):443-7. PubMed ID: 20421335
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy.
    Wieben ED; Aleff RA; Tang X; Butz ML; Kalari KR; Highsmith EW; Jen J; Vasmatzis G; Patel SV; Maguire LJ; Baratz KH; Fautsch MP
    Invest Ophthalmol Vis Sci; 2017 Jan; 58(1):343-352. PubMed ID: 28118661
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.