BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 21789751)

  • 1. [Synthetic lethality as a new concept for the treatment of cancer].
    Herter-Sprie GS; Chen S; Höpker K; Reinhardt HC
    Dtsch Med Wochenschr; 2011 Jul; 136(30):1526-30. PubMed ID: 21789751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthetic lethality strategies: Beyond BRCA1/2 mutations in pancreatic cancer.
    Hu Y; Guo M
    Cancer Sci; 2020 Sep; 111(9):3111-3121. PubMed ID: 32639661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the DNA damage response in oncology: past, present and future perspectives.
    Basu B; Yap TA; Molife LR; de Bono JS
    Curr Opin Oncol; 2012 May; 24(3):316-24. PubMed ID: 22476188
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting DNA repair and replication stress in the treatment of ovarian cancer.
    Murai J
    Int J Clin Oncol; 2017 Aug; 22(4):619-628. PubMed ID: 28643177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PARPi focus the spotlight on replication fork protection in cancer.
    Schlacher K
    Nat Cell Biol; 2017 Oct; 19(11):1309-1310. PubMed ID: 29087384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An Achilles' heel for breast cancer?
    Caldecott KW; Chalmers A
    Nat Struct Mol Biol; 2005 May; 12(5):387-8. PubMed ID: 15870726
    [No Abstract]   [Full Text] [Related]  

  • 7. Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor.
    Ogiwara H; Ui A; Shiotani B; Zou L; Yasui A; Kohno T
    Carcinogenesis; 2013 Nov; 34(11):2486-97. PubMed ID: 23825154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PARP inhibitors: targeting the right patients.
    Azvolinsky A
    J Natl Cancer Inst; 2012 Dec; 104(24):1851-2. PubMed ID: 23231976
    [No Abstract]   [Full Text] [Related]  

  • 9. c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance.
    Pyndiah S; Tanida S; Ahmed KM; Cassimere EK; Choe C; Sakamuro D
    Sci Signal; 2011 Mar; 4(166):ra19. PubMed ID: 21447800
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthetic lethality to overcome cancer drug resistance.
    Porcelli L; Quatrale AE; Mantuano P; Silvestris N; Brunetti AE; Calvert H; Paradiso A; Azzariti A
    Curr Med Chem; 2012; 19(23):3858-73. PubMed ID: 22788762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?
    Bouwman P; Jonkers J
    Clin Cancer Res; 2014 Feb; 20(3):540-7. PubMed ID: 24270682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA damage repair in breast cancer and its therapeutic implications.
    Ali R; Rakha EA; Madhusudan S; Bryant HE
    Pathology; 2017 Feb; 49(2):156-165. PubMed ID: 28034453
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G; Yao L; Ruan K; Song G; Mao Y; Bao S
    Cell Biol Int; 2009 Dec; 33(12):1237-44. PubMed ID: 19732843
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.
    Peralta-Leal A; Rodríguez-Vargas JM; Aguilar-Quesada R; Rodríguez MI; Linares JL; de Almodóvar MR; Oliver FJ
    Free Radic Biol Med; 2009 Jul; 47(1):13-26. PubMed ID: 19362586
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2.
    Drew Y; Mulligan EA; Vong WT; Thomas HD; Kahn S; Kyle S; Mukhopadhyay A; Los G; Hostomsky Z; Plummer ER; Edmondson RJ; Curtin NJ
    J Natl Cancer Inst; 2011 Feb; 103(4):334-46. PubMed ID: 21183737
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of long patch base excision repair pathway.
    Mohapatra P; Satapathy SR; Das D; Siddharth S; Choudhuri T; Kundu CN
    Toxicol Appl Pharmacol; 2014 Mar; 275(3):221-31. PubMed ID: 24467951
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (HIMOXOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells.
    Lisiak N; Paszel-Jaworska A; Bednarczyk-Cwynar B; Zaprutko L; Kaczmarek M; Rybczyńska M
    Chem Biol Interact; 2014 Feb; 208():47-57. PubMed ID: 24291674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PARP inhibitors: will the new class of drugs match the hype?
    Tuma RS
    J Natl Cancer Inst; 2009 Sep; 101(18):1230-2. PubMed ID: 19738163
    [No Abstract]   [Full Text] [Related]  

  • 19. BRCA1 and BRCA2 mutation type associated with cancer risk.
    Burki TK
    Lancet Oncol; 2015 May; 16(5):e205. PubMed ID: 25892146
    [No Abstract]   [Full Text] [Related]  

  • 20. DNA REPAIR. Drugging DNA repair.
    Jackson SP; Helleday T
    Science; 2016 Jun; 352(6290):1178-9. PubMed ID: 27257245
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.