These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 21791338)

  • 1. Metabolic study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to the enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in vitro in human bronchial epithelial cells using chiral capillary electrophoresis.
    Yang Y; Yu C; Zhou M; Pang N; Li N; Nie H; Liao J; Bai Y; Liu H
    J Chromatogr A; 2011 Sep; 1218(37):6505-10. PubMed ID: 21791338
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Lao Y; Yu N; Kassie F; Villalta PW; Hecht SS
    Chem Res Toxicol; 2007 Feb; 20(2):235-45. PubMed ID: 17305407
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P; Kalscheuer S; Hochalter JB; Villalta PW; Hecht SS
    Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG; Borukhova A; Akerkar SA; Hecht SS
    Cancer Epidemiol Biomarkers Prev; 1997 Feb; 6(2):113-20. PubMed ID: 9037562
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in bile duct-cannulated rats: stereoselective metabolism and tissue distribution.
    Wu Z; Upadhyaya P; Carmella SG; Hecht SS; Zimmerman CL
    Carcinogenesis; 2002 Jan; 23(1):171-9. PubMed ID: 11756238
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stereoselective metabolism and tissue retention in rats of the individual enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Zimmerman CL; Wu Z; Upadhyaya P; Hecht SS
    Carcinogenesis; 2004 Jul; 25(7):1237-42. PubMed ID: 14988218
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Zhang S; Wang M; Villalta PW; Lindgren BR; Upadhyaya P; Lao Y; Hecht SS
    Chem Res Toxicol; 2009 May; 22(5):926-36. PubMed ID: 19358518
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR; Ding X; Murphy SE
    Drug Metab Dispos; 2003 Oct; 31(10):1199-202. PubMed ID: 12975327
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Formation and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers in vitro in mouse, rat and human tissues.
    Upadhyaya P; Carmella SG; Guengerich FP; Hecht SS
    Carcinogenesis; 2000 Jun; 21(6):1233-8. PubMed ID: 10837015
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E; Engl J; Friesenegger S; Tricker AR
    Chem Res Toxicol; 2009 Jun; 22(6):1008-17. PubMed ID: 19408892
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P; Kenney PM; Hochalter JB; Wang M; Hecht SS
    Carcinogenesis; 1999 Aug; 20(8):1577-82. PubMed ID: 10426810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.
    Breyer-Pfaff U; Martin HJ; Ernst M; Maser E
    Drug Metab Dispos; 2004 Sep; 32(9):915-22. PubMed ID: 15319331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intestinal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats: Sex difference, inducibility and inhibition by phenethylisothiocyanate.
    Schulze J; Malone A; Richter E
    Carcinogenesis; 1995 Aug; 16(8):1733-40. PubMed ID: 7634397
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stereospecific Metabolism of the Tobacco-Specific Nitrosamine, NNAL.
    Kozlovich S; Chen G; Lazarus P
    Chem Res Toxicol; 2015 Nov; 28(11):2112-9. PubMed ID: 26452127
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.
    Balbo S; Johnson CS; Kovi RC; James-Yi SA; O'Sullivan MG; Wang M; Le CT; Khariwala SS; Upadhyaya P; Hecht SS
    Carcinogenesis; 2014 Dec; 35(12):2798-806. PubMed ID: 25269804
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Ma B; Zarth AT; Carlson ES; Villalta PW; Upadhyaya P; Stepanov I; Hecht SS
    Chem Res Toxicol; 2018 Jan; 31(1):48-57. PubMed ID: 29131934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
    Prokopczyk B; Trushin N; Leszczynska J; Waggoner SE; El-Bayoumy K
    Carcinogenesis; 2001 Jan; 22(1):107-14. PubMed ID: 11159748
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Use of precision-cut tissue slices in organ culture to study metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by hamster lung, liver and kidney.
    Richter E; Friesenegger S; Engl J; Tricker AR
    Toxicology; 2000 Apr; 144(1-3):83-91. PubMed ID: 10781874
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biotransformation and transport of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in bile duct-cannulated wild-type and Mrp2/Abcc2-deficient (TR ) Wistar rats.
    Leslie EM; Ghibellini G; Nezasa K; Brouwer KL
    Carcinogenesis; 2007 Dec; 28(12):2650-6. PubMed ID: 17724374
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stereochemistry of metabolites of a tobacco-specific lung carcinogen in smokers' urine.
    Carmella SG; Ye M; Upadhyaya P; Hecht SS
    Cancer Res; 1999 Aug; 59(15):3602-5. PubMed ID: 10446969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.