These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
290 related articles for article (PubMed ID: 21795339)
1. Enterovirus 71 and coxsackievirus A16 3C proteases: binding to rupintrivir and their substrates and anti-hand, foot, and mouth disease virus drug design. Lu G; Qi J; Chen Z; Xu X; Gao F; Lin D; Qian W; Liu H; Jiang H; Yan J; Gao GF J Virol; 2011 Oct; 85(19):10319-31. PubMed ID: 21795339 [TBL] [Abstract][Full Text] [Related]
2. Crystal structures of enterovirus 71 3C protease complexed with rupintrivir reveal the roles of catalytically important residues. Wang J; Fan T; Yao X; Wu Z; Guo L; Lei X; Wang J; Wang M; Jin Q; Cui S J Virol; 2011 Oct; 85(19):10021-30. PubMed ID: 21813612 [TBL] [Abstract][Full Text] [Related]
3. Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir. Wu C; Cai Q; Chen C; Li N; Peng X; Cai Y; Yin K; Chen X; Wang X; Zhang R; Liu L; Chen S; Li J; Lin T Acta Crystallogr D Biol Crystallogr; 2013 May; 69(Pt 5):866-71. PubMed ID: 23633597 [TBL] [Abstract][Full Text] [Related]
4. Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor. Wang Y; Cao L; Zhai Y; Yin Z; Sun Y; Shang L Antimicrob Agents Chemother; 2017 Jul; 61(7):. PubMed ID: 28461310 [TBL] [Abstract][Full Text] [Related]
5. Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93. Costenaro L; Kaczmarska Z; Arnan C; Janowski R; Coutard B; Solà M; Gorbalenya AE; Norder H; Canard B; Coll M J Virol; 2011 Oct; 85(20):10764-73. PubMed ID: 21835784 [TBL] [Abstract][Full Text] [Related]
6. Structure of the HRV-C 3C-Rupintrivir Complex Provides New Insights for Inhibitor Design. Yuan S; Fan K; Chen Z; Sun Y; Hou H; Zhu L Virol Sin; 2020 Aug; 35(4):445-454. PubMed ID: 32103448 [TBL] [Abstract][Full Text] [Related]
7. Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study. Ang MJ; Lau QY; Ng FM; Then SW; Poulsen A; Cheong YK; Ngoh ZX; Tan YW; Peng J; Keller TH; Hill J; Chu JJ; Chia CS J Enzyme Inhib Med Chem; 2016; 31(2):332-9. PubMed ID: 25792507 [TBL] [Abstract][Full Text] [Related]
8. Susceptibility of inhibitors against 3C protease of coxsackievirus A16 and enterovirus A71 causing hand, foot and mouth disease: A molecular dynamics study. Jetsadawisut W; Nutho B; Meeprasert A; Rungrotmongkol T; Kungwan N; Wolschann P; Hannongbua S Biophys Chem; 2016 Dec; 219():9-16. PubMed ID: 27668727 [TBL] [Abstract][Full Text] [Related]
9. Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening. Ma GH; Ye Y; Zhang D; Xu X; Si P; Peng JL; Xiao YL; Cao RY; Yin YL; Chen J; Zhao LX; Zhou Y; Zhong W; Liu H; Luo XM; Chen LL; Shen X Eur J Med Chem; 2016 Nov; 124():981-991. PubMed ID: 27776325 [TBL] [Abstract][Full Text] [Related]
10. Glycyrrhizic acid as the antiviral component of Glycyrrhiza uralensis Fisch. against coxsackievirus A16 and enterovirus 71 of hand foot and mouth disease. Wang J; Chen X; Wang W; Zhang Y; Yang Z; Jin Y; Ge HM; Li E; Yang G J Ethnopharmacol; 2013 May; 147(1):114-21. PubMed ID: 23454684 [TBL] [Abstract][Full Text] [Related]
11. Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode. Lockbaum GJ; Henes M; Lee JM; Timm J; Nalivaika EA; Thompson PR; Kurt Yilmaz N; Schiffer CA Biochemistry; 2021 Oct; 60(39):2925-2931. PubMed ID: 34506130 [TBL] [Abstract][Full Text] [Related]
12. Rupintrivir is a promising candidate for treating severe cases of Enterovirus-71 infection. Zhang XN; Song ZG; Jiang T; Shi BS; Hu YW; Yuan ZH World J Gastroenterol; 2010 Jan; 16(2):201-9. PubMed ID: 20066739 [TBL] [Abstract][Full Text] [Related]
13. A Novel Enterovirus 71 (EV71) Virulence Determinant: The 69th Residue of 3C Protease Modulates Pathogenicity. Li B; Yue Y; Zhang Y; Yuan Z; Li P; Song N; Lin W; Liu Y; Gu L; Meng H Front Cell Infect Microbiol; 2017; 7():26. PubMed ID: 28217559 [TBL] [Abstract][Full Text] [Related]
14. Insights into cleavage specificity from the crystal structure of foot-and-mouth disease virus 3C protease complexed with a peptide substrate. Zunszain PA; Knox SR; Sweeney TR; Yang J; Roqué-Rosell N; Belsham GJ; Leatherbarrow RJ; Curry S J Mol Biol; 2010 Jan; 395(2):375-89. PubMed ID: 19883658 [TBL] [Abstract][Full Text] [Related]
15. Crystal Structures of Yeast-Produced Enterovirus 71 and Enterovirus 71/Coxsackievirus A16 Chimeric Virus-Like Particles Provide the Structural Basis for Novel Vaccine Design against Hand-Foot-and-Mouth Disease. Lyu K; He YL; Li HY; Chen R J Virol; 2015 Jun; 89(12):6196-208. PubMed ID: 25833050 [TBL] [Abstract][Full Text] [Related]
16. An open conformation determined by a structural switch for 2A protease from coxsackievirus A16. Sun Y; Wang X; Yuan S; Dang M; Li X; Zhang XC; Rao Z Protein Cell; 2013 Oct; 4(10):782-92. PubMed ID: 24026848 [TBL] [Abstract][Full Text] [Related]
17. Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71. Zhang L; Huang G; Cai Q; Zhao C; Tang L; Ren H; Li P; Li N; Huang J; Chen X; Guan Y; You H; Chen S; Li J; Lin T J Mol Recognit; 2016 Nov; 29(11):520-527. PubMed ID: 27185390 [TBL] [Abstract][Full Text] [Related]
18. Crystal structure of human enterovirus 71 3C protease. Cui S; Wang J; Fan T; Qin B; Guo L; Lei X; Wang J; Wang M; Jin Q J Mol Biol; 2011 May; 408(3):449-61. PubMed ID: 21396941 [TBL] [Abstract][Full Text] [Related]
19. The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon. Rocha-Pereira J; Nascimento MS; Ma Q; Hilgenfeld R; Neyts J; Jochmans D Antimicrob Agents Chemother; 2014 Aug; 58(8):4675-81. PubMed ID: 24890597 [TBL] [Abstract][Full Text] [Related]
20. Computational Screening of Newly Designed Compounds against Coxsackievirus A16 and Enterovirus A71. Sripattaraphan A; Sanachai K; Chavasiri W; Boonyasuppayakorn S; Maitarad P; Rungrotmongkol T Molecules; 2022 Mar; 27(6):. PubMed ID: 35335272 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]