156 related articles for article (PubMed ID: 21802957)
41. The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells--preliminary comparisons to paclitaxel.
Balachandran R; ter Haar E; Welsh MJ; Grant SG; Day BW
Anticancer Drugs; 1998 Jan; 9(1):67-76. PubMed ID: 9491794
[TBL] [Abstract][Full Text] [Related]
42. Synthesis and Cytotoxicity Evaluation of C4- and C5-Modified Analogues of the α,β-Unsaturated Lactone of Pironetin.
Huang DS; Wong HL; Georg GI
ChemMedChem; 2017 Apr; 12(7):520-528. PubMed ID: 28261964
[TBL] [Abstract][Full Text] [Related]
43. A common pharmacophore for cytotoxic natural products that stabilize microtubules.
Ojima I; Chakravarty S; Inoue T; Lin S; He L; Horwitz SB; Kuduk SD; Danishefsky SJ
Proc Natl Acad Sci U S A; 1999 Apr; 96(8):4256-61. PubMed ID: 10200249
[TBL] [Abstract][Full Text] [Related]
44. Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners.
Nadaradjane C; Yang CH; Rodriguez-Gabin A; Ye K; Sugasawa K; Atasoylu O; Smith AB; Horwitz SB; McDaid HM
J Nat Prod; 2018 Mar; 81(3):607-615. PubMed ID: 29522336
[TBL] [Abstract][Full Text] [Related]
45. Discodermolide interferes with the binding of tau protein to microtubules.
Kar S; Florence GJ; Paterson I; Amos LA
FEBS Lett; 2003 Mar; 539(1-3):34-6. PubMed ID: 12650922
[TBL] [Abstract][Full Text] [Related]
46. Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.
Honore S; Kamath K; Braguer D; Horwitz SB; Wilson L; Briand C; Jordan MA
Cancer Res; 2004 Jul; 64(14):4957-64. PubMed ID: 15256469
[TBL] [Abstract][Full Text] [Related]
47. Solution structure of (+)-discodermolide.
Smith AB; LaMarche MJ; Falcone-Hindley M
Org Lett; 2001 Mar; 3(5):695-8. PubMed ID: 11259039
[TBL] [Abstract][Full Text] [Related]
48. A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel.
Dabydeen DA; Florence GJ; Paterson I; Hamel E
Cancer Chemother Pharmacol; 2004 May; 53(5):397-403. PubMed ID: 15060743
[TBL] [Abstract][Full Text] [Related]
49. Deconstruction-reconstruction strategy for accessing valuable polyketides. Preparation of the C15-C24 stereopentad of discodermolide.
Parker KA; Wang P
Org Lett; 2007 Nov; 9(23):4793-6. PubMed ID: 17924640
[TBL] [Abstract][Full Text] [Related]
50. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
Buey RM; Calvo E; Barasoain I; Pineda O; Edler MC; Matesanz R; Cerezo G; Vanderwal CD; Day BW; Sorensen EJ; López JA; Andreu JM; Hamel E; Díaz JF
Nat Chem Biol; 2007 Feb; 3(2):117-25. PubMed ID: 17206139
[TBL] [Abstract][Full Text] [Related]
51. Discodermolide analogues as the chemical component of combination bacteriolytic therapy.
Smith AB; Freeze BS; LaMarche MJ; Sager J; Kinzler KW; Vogelstein B
Bioorg Med Chem Lett; 2005 Aug; 15(15):3623-6. PubMed ID: 15979874
[TBL] [Abstract][Full Text] [Related]
52. Conception, synthesis, and biological evaluation of original discodermolide analogues.
de Lemos E; Agouridas E; Sorin G; Guerreiro A; Commerçon A; Pancrazi A; Betzer JF; Lannou MI; Ardisson J
Chemistry; 2011 Aug; 17(36):10123-34. PubMed ID: 21793059
[TBL] [Abstract][Full Text] [Related]
53. Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide.
Minguez JM; Giuliano KA; Balachandran R; Madiraju C; Curran DP; Day BW
Mol Cancer Ther; 2002 Dec; 1(14):1305-13. PubMed ID: 12516963
[TBL] [Abstract][Full Text] [Related]
54. Studies directed toward the total synthesis of discodermolide: asymmetric synthesis of the C1-C14 fragment.
Arefolov A; Panek JS
Org Lett; 2002 Jul; 4(14):2397-400. PubMed ID: 12098256
[TBL] [Abstract][Full Text] [Related]
55. Regulated-stereoselective construction of thirteen stereogenic centers necessary for the frame of (+)-discodermolide, based on iterative Lewis acid-promoted aldol reactions.
Kiyooka S; Shahid KA; Goto F; Okazaki M; Shuto Y
J Org Chem; 2003 Oct; 68(21):7967-78. PubMed ID: 14535772
[TBL] [Abstract][Full Text] [Related]
56. 1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide.
Paterson I; Delgado O; Florence GJ; Lyothier I; Scott JP; Sereinig N
Org Lett; 2003 Jan; 5(1):35-8. PubMed ID: 12509884
[TBL] [Abstract][Full Text] [Related]
57. Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
Paterson I; Naylor GJ; Wright AE
Chem Commun (Camb); 2008 Oct; (38):4628-30. PubMed ID: 18815706
[TBL] [Abstract][Full Text] [Related]
58. Semisynthetic analogues of the microtubule-stabilizing agent discodermolide: preparation and biological activity.
Gunasekera SP; Longley RE; Isbrucker RA
J Nat Prod; 2002 Dec; 65(12):1830-7. PubMed ID: 12502323
[TBL] [Abstract][Full Text] [Related]
59. Efficient strategy for the synthesis of stereopentad subunits of scytophycin, rifamycin S, and discodermolide.
BouzBouz S; Cossy J
Org Lett; 2001 Dec; 3(25):3995-8. PubMed ID: 11735568
[TBL] [Abstract][Full Text] [Related]
60. Scalable, catalytic asymmetric synthesis of syn, anti stereotriad building blocks for polypropionate antibiotics.
Parker KA; Cao H
Org Lett; 2006 Aug; 8(16):3541-4. PubMed ID: 16869655
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
