BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 21804608)

  • 1. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin.
    Huertas D; Soler M; Moreto J; Villanueva A; Martinez A; Vidal A; Charlton M; Moffat D; Patel S; McDermott J; Owen J; Brotherton D; Krige D; Cuthill S; Esteller M
    Oncogene; 2012 Mar; 31(11):1408-18. PubMed ID: 21804608
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Autoinhibition and Polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase Haspin to mitosis.
    Ghenoiu C; Wheelock MS; Funabiki H
    Mol Cell; 2013 Dec; 52(5):734-45. PubMed ID: 24184212
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of novel N1-acylated 5-(4-pyridinyl)indazole derivatives as potent and selective haspin inhibitors.
    Shawky MM; Abdallah M; Khalifa H; Aboushady Y; Abadi AH; Engel M; Abdel-Halim M
    Bioorg Chem; 2024 Apr; 145():107235. PubMed ID: 38447464
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity.
    Melms JC; Vallabhaneni S; Mills CE; Yapp C; Chen JY; Morelli E; Waszyk P; Kumar S; Deming D; Moret N; Rodriguez S; Subramanian K; Rogava M; Cartwright ANR; Luoma A; Mei S; Brinker TJ; Miller DM; Spektor A; Schadendorf D; Riggi N; Wucherpfennig KW; Sorger PK; Izar B
    Cancer Res; 2020 Feb; 80(4):798-810. PubMed ID: 31882401
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors.
    Lavogina D; Kestav K; Chaikuad A; Heroven C; Knapp S; Uri A
    Acta Crystallogr F Struct Biol Commun; 2016 May; 72(Pt 5):339-45. PubMed ID: 27139824
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N
    Aboelfotouh HG; Abdallah M; Khalifa H; Aboushady Y; Abadi AH; Engel M; Abdel-Halim M
    Arch Pharm (Weinheim); 2024 Jun; 357(6):e2400020. PubMed ID: 38478964
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation.
    Harris RJ; Heer M; Levasseur MD; Cartwright TN; Weston B; Mitchell JL; Coxhead JM; Gaughan L; Prendergast L; Rico D; Higgins JMG
    Nat Commun; 2023 Nov; 14(1):7243. PubMed ID: 37945563
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Global phosphoproteomic analysis identified key kinases regulating male meiosis in mouse.
    Li H; Chen H; Zhang X; Qi Y; Wang B; Cui Y; Ren J; Zhao Y; Chen Y; Zhu T; Wang Y; Yao L; Guo Y; Zhu H; Li Y; Situ C; Guo X
    Cell Mol Life Sci; 2022 Aug; 79(8):467. PubMed ID: 35930080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure, function and evolution of haspin and haspin-related proteins, a distinctive group of eukaryotic protein kinases.
    Higgins JM
    Cell Mol Life Sci; 2003 Mar; 60(3):446-62. PubMed ID: 12737306
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Haspin kinase binds to a nucleosomal DNA supergroove.
    Hicks CW; Gliech CR; Zhang X; Rahman S; Vasquez S; Holland AJ; Wolberger C
    bioRxiv; 2024 May; ():. PubMed ID: 38826405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Haspin balances the ratio of asymmetric cell division through Wnt5a and regulates cell fate decisions in mouse embryonic stem cells.
    Gao Y; Ma B; Li Y; Wu X; Zhao S; Guo H; Wang Y; Sun L; Xie J
    Cell Death Discov; 2023 Aug; 9(1):307. PubMed ID: 37612272
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combined HASPIN and mTOR inhibition is synergistic against KRAS-driven carcinomas.
    Xu C; Gao Q; Wu Z; Lou W; Li X; Wang M; Wang N; Li Q
    Transl Oncol; 2022 Dec; 26():101540. PubMed ID: 36115073
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.
    Sayegh J; Cao J; Zou MR; Morales A; Blair LP; Norcia M; Hoyer D; Tackett AJ; Merkel JS; Yan Q
    J Biol Chem; 2013 Mar; 288(13):9408-17. PubMed ID: 23408432
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone acetylation and DNA demethylation of T cells result in an anaplastic large cell lymphoma-like phenotype.
    Joosten M; Seitz V; Zimmermann K; Sommerfeld A; Berg E; Lenze D; Leser U; Stein H; Hummel M
    Haematologica; 2013 Feb; 98(2):247-54. PubMed ID: 22899583
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B.
    De Antoni A; Maffini S; Knapp S; Musacchio A; Santaguida S
    J Cell Biol; 2012 Oct; 199(2):269-84. PubMed ID: 23071153
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation.
    Wang F; Ulyanova NP; Daum JR; Patnaik D; Kateneva AV; Gorbsky GJ; Higgins JM
    J Cell Biol; 2012 Oct; 199(2):251-68. PubMed ID: 23071152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors.
    Cuny GD; Ulyanova NP; Patnaik D; Liu JF; Lin X; Auerbach K; Ray SS; Xian J; Glicksman MA; Stein RL; Higgins JM
    Bioorg Med Chem Lett; 2012 Mar; 22(5):2015-9. PubMed ID: 22335895
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes.
    Nguyen AL; Gentilello AS; Balboula AZ; Shrivastava V; Ohring J; Schindler K
    J Cell Sci; 2014 Dec; 127(Pt 23):5066-78. PubMed ID: 25315835
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polo-like kinase-1 triggers histone phosphorylation by Haspin in mitosis.
    Zhou L; Tian X; Zhu C; Wang F; Higgins JM
    EMBO Rep; 2014 Mar; 15(3):273-81. PubMed ID: 24413556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of the chromatin phosphoproteome by the Haspin protein kinase.
    Maiolica A; de Medina-Redondo M; Schoof EM; Chaikuad A; Villa F; Gatti M; Jeganathan S; Lou HJ; Novy K; Hauri S; Toprak UH; Herzog F; Meraldi P; Penengo L; Turk BE; Knapp S; Linding R; Aebersold R
    Mol Cell Proteomics; 2014 Jul; 13(7):1724-40. PubMed ID: 24732914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.