306 related articles for article (PubMed ID: 21806015)
1. Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.
Kostrhunova H; Malina J; Pickard AJ; Stepankova J; Vojtiskova M; Kasparkova J; Muchova T; Rohlfing ML; Bierbach U; Brabec V
Mol Pharm; 2011 Oct; 8(5):1941-54. PubMed ID: 21806015
[TBL] [Abstract][Full Text] [Related]
2. Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent.
Baruah H; Wright MW; Bierbach U
Biochemistry; 2005 Apr; 44(16):6059-70. PubMed ID: 15835895
[TBL] [Abstract][Full Text] [Related]
3. Processing and Bypass of a Site-Specific DNA Adduct of the Cytotoxic Platinum-Acridinylthiourea Conjugate by Polymerases Involved in DNA Repair: Biochemical and Thermodynamic Aspects.
Hreusova M; Brabec V; Novakova O
Int J Mol Sci; 2021 Oct; 22(19):. PubMed ID: 34639179
[TBL] [Abstract][Full Text] [Related]
4. Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent.
Barry CG; Baruah H; Bierbach U
J Am Chem Soc; 2003 Aug; 125(32):9629-37. PubMed ID: 12904029
[TBL] [Abstract][Full Text] [Related]
5. Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.
Mlcouskova J; Malina J; Novohradsky V; Kasparkova J; Komeda S; Brabec V
Biochim Biophys Acta; 2012 Oct; 1820(10):1502-11. PubMed ID: 22683702
[TBL] [Abstract][Full Text] [Related]
6. DNA metalating-intercalating hybrid agents for the treatment of chemoresistant cancers.
Suryadi J; Bierbach U
Chemistry; 2012 Oct; 18(41):12926-34. PubMed ID: 22987397
[TBL] [Abstract][Full Text] [Related]
7. PT-ACRAMTU, a platinum-acridine anticancer agent, lengthens and aggregates, but does not stiffen or soften DNA.
Dutta S; Snyder MJ; Rosile D; Binz KL; Roll EH; Suryadi J; Bierbach U; Guthold M
Cell Biochem Biophys; 2013; 67(3):1103-13. PubMed ID: 23636685
[TBL] [Abstract][Full Text] [Related]
8. DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.
Kasparkova J; Novakova O; Farrell N; Brabec V
Biochemistry; 2003 Jan; 42(3):792-800. PubMed ID: 12534292
[TBL] [Abstract][Full Text] [Related]
9. Spontaneous translocation of antitumor oxaliplatin, its enantiomeric analogue, and Cisplatin from one strand to another in double-helical DNA.
Malina J; Natile G; Brabec V
Chemistry; 2013 Sep; 19(36):11984-91. PubMed ID: 23873652
[TBL] [Abstract][Full Text] [Related]
10. DNA minor groove adducts formed by a platinum-acridine conjugate inhibit association of tata-binding protein with its cognate sequence.
Budiman ME; Bierbach U; Alexander RW
Biochemistry; 2005 Aug; 44(33):11262-8. PubMed ID: 16101310
[TBL] [Abstract][Full Text] [Related]
11. cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.
Lovejoy KS; Todd RC; Zhang S; McCormick MS; D'Aquino JA; Reardon JT; Sancar A; Giacomini KM; Lippard SJ
Proc Natl Acad Sci U S A; 2008 Jul; 105(26):8902-7. PubMed ID: 18579768
[TBL] [Abstract][Full Text] [Related]
12. Metal-intercalator-mediated self-association and one-dimensional aggregation in the structure of the excised major DNA adduct of a platinum-acridine agent.
Baruah H; Day CS; Wright MW; Bierbach U
J Am Chem Soc; 2004 Apr; 126(14):4492-3. PubMed ID: 15070347
[TBL] [Abstract][Full Text] [Related]
13. DNA-protein cross-linking by trans-[PtCl(2)(E-iminoether)(2)]. A concept for activation of the trans geometry in platinum antitumor complexes.
Novakova O; Kasparkova J; Malina J; Natile G; Brabec V
Nucleic Acids Res; 2003 Nov; 31(22):6450-60. PubMed ID: 14602903
[TBL] [Abstract][Full Text] [Related]
14. Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay.
Choudhury JR; Rao L; Bierbach U
J Biol Inorg Chem; 2011 Mar; 16(3):373-80. PubMed ID: 21086002
[TBL] [Abstract][Full Text] [Related]
15. A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.
Ma Z; Choudhury JR; Wright MW; Day CS; Saluta G; Kucera GL; Bierbach U
J Med Chem; 2008 Dec; 51(23):7574-80. PubMed ID: 19012390
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.
Guddneppanavar R; Saluta G; Kucera GL; Bierbach U
J Med Chem; 2006 Jun; 49(11):3204-14. PubMed ID: 16722638
[TBL] [Abstract][Full Text] [Related]
17. Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases Across a Lesion of Antitumor Platinum-Acridine Complex.
Hreusova M; Novakova O; Brabec V
Int J Mol Sci; 2020 Oct; 21(20):. PubMed ID: 33096927
[TBL] [Abstract][Full Text] [Related]
18. Monofunctional platinum-DNA adducts are strong inhibitors of transcription and substrates for nucleotide excision repair in live mammalian cells.
Zhu G; Myint M; Ang WH; Song L; Lippard SJ
Cancer Res; 2012 Feb; 72(3):790-800. PubMed ID: 22180496
[TBL] [Abstract][Full Text] [Related]
19. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
Hegmans A; Berners-Price SJ; Davies MS; Thomas DS; Humphreys AS; Farrell N
J Am Chem Soc; 2004 Feb; 126(7):2166-80. PubMed ID: 14971952
[TBL] [Abstract][Full Text] [Related]
20. DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.
Kasparkova J; Marini V; Najajreh Y; Gibson D; Brabec V
Biochemistry; 2003 May; 42(20):6321-32. PubMed ID: 12755637
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
