251 related articles for article (PubMed ID: 21806996)
1. The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder.
Schneider EV; Böttcher J; Blaesse M; Neumann L; Huber R; Maskos K
J Mol Biol; 2011 Sep; 412(2):251-66. PubMed ID: 21806996
[TBL] [Abstract][Full Text] [Related]
2. Structure of the mediator subunit cyclin C and its implications for CDK8 function.
Hoeppner S; Baumli S; Cramer P
J Mol Biol; 2005 Jul; 350(5):833-42. PubMed ID: 15979093
[TBL] [Abstract][Full Text] [Related]
3. All-atomic molecular dynamic studies of human CDK8: insight into the A-loop, point mutations and binding with its partner CycC.
Xu W; Amire-Brahimi B; Xie XJ; Huang L; Ji JY
Comput Biol Chem; 2014 Aug; 51():1-11. PubMed ID: 24754906
[TBL] [Abstract][Full Text] [Related]
4. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
Park MJ; Shen H; Spaeth JM; Tolvanen JH; Failor C; Knudtson JF; McLaughlin J; Halder SK; Yang Q; Bulun SE; Al-Hendy A; Schenken RS; Aaltonen LA; Boyer TG
J Biol Chem; 2018 Mar; 293(13):4870-4882. PubMed ID: 29440396
[TBL] [Abstract][Full Text] [Related]
5. A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery.
Cholko T; Chen W; Tang Z; Chang CA
J Comput Aided Mol Des; 2018 Jun; 32(6):671-685. PubMed ID: 29737445
[TBL] [Abstract][Full Text] [Related]
6. Structure-kinetic relationship study of CDK8/CycC specific compounds.
Schneider EV; Böttcher J; Huber R; Maskos K; Neumann L
Proc Natl Acad Sci U S A; 2013 May; 110(20):8081-6. PubMed ID: 23630251
[TBL] [Abstract][Full Text] [Related]
7. Cyclin C influences the timing of mitosis in fission yeast.
Banyai G; Szilagyi Z; Baraznenok V; Khorosjutina O; Gustafsson CM
Mol Biol Cell; 2017 Jul; 28(13):1738-1744. PubMed ID: 28515143
[TBL] [Abstract][Full Text] [Related]
8. Mediator kinase module and human tumorigenesis.
Clark AD; Oldenbroek M; Boyer TG
Crit Rev Biochem Mol Biol; 2015; 50(5):393-426. PubMed ID: 26182352
[TBL] [Abstract][Full Text] [Related]
9. The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription.
Li X; Liu M; Ren X; Loncle N; Wang Q; Hemba-Waduge RU; Yu SH; Boube M; Bourbon HG; Ni JQ; Ji JY
PLoS Genet; 2020 May; 16(5):e1008832. PubMed ID: 32463833
[TBL] [Abstract][Full Text] [Related]
10. Distinct roles for Mediator Cdk8 module subunits in Drosophila development.
Loncle N; Boube M; Joulia L; Boschiero C; Werner M; Cribbs DL; Bourbon HM
EMBO J; 2007 Feb; 26(4):1045-54. PubMed ID: 17290221
[TBL] [Abstract][Full Text] [Related]
11. A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.
Klatt F; Leitner A; Kim IV; Ho-Xuan H; Schneider EV; Langhammer F; Weinmann R; Müller MR; Huber R; Meister G; Kuhn CD
Proc Natl Acad Sci U S A; 2020 Feb; 117(6):2894-2905. PubMed ID: 31988137
[TBL] [Abstract][Full Text] [Related]
12. Human cyclin C protein is stabilized by its associated kinase cdk8, independently of its catalytic activity.
Barette C; Jariel-Encontre I; Piechaczyk M; Piette J
Oncogene; 2001 Feb; 20(5):551-62. PubMed ID: 11313987
[TBL] [Abstract][Full Text] [Related]
13. Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila.
Kuuluvainen E; Hakala H; Havula E; Sahal Estimé M; Rämet M; Hietakangas V; Mäkelä TP
J Biol Chem; 2014 Jun; 289(23):16252-61. PubMed ID: 24778181
[TBL] [Abstract][Full Text] [Related]
14. Dysregulation of CDK8 and Cyclin C in tumorigenesis.
Xu W; Ji JY
J Genet Genomics; 2011 Oct; 38(10):439-52. PubMed ID: 22035865
[TBL] [Abstract][Full Text] [Related]
15. CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila.
Xie XJ; Hsu FN; Gao X; Xu W; Ni JQ; Xing Y; Huang L; Hsiao HC; Zheng H; Wang C; Zheng Y; Xiaoli AM; Yang F; Bondos SE; Ji JY
PLoS Biol; 2015 Jul; 13(7):e1002207. PubMed ID: 26222308
[TBL] [Abstract][Full Text] [Related]
16. Distinct effects of CDK8 module subunits on cellular growth and proliferation in
Li X; Liu M; Xing Y; Niu Y; Liu TH; Sun JL; Liu Y; Hemba-Waduge RU; Ji JY
bioRxiv; 2024 May; ():. PubMed ID: 38746212
[TBL] [Abstract][Full Text] [Related]
17. The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II.
Elmlund H; Baraznenok V; Lindahl M; Samuelsen CO; Koeck PJ; Holmberg S; Hebert H; Gustafsson CM
Proc Natl Acad Sci U S A; 2006 Oct; 103(43):15788-93. PubMed ID: 17043218
[TBL] [Abstract][Full Text] [Related]
18. CYCLIN-DEPENDENT KINASE8 differentially regulates plant immunity to fungal pathogens through kinase-dependent and -independent functions in Arabidopsis.
Zhu Y; Schluttenhoffer CM; Wang P; Fu F; Thimmapuram J; Zhu JK; Lee SY; Yun DJ; Mengiste T
Plant Cell; 2014 Oct; 26(10):4149-70. PubMed ID: 25281690
[TBL] [Abstract][Full Text] [Related]
19. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.
Jeffrey PD; Russo AA; Polyak K; Gibbs E; Hurwitz J; Massagué J; Pavletich NP
Nature; 1995 Jul; 376(6538):313-20. PubMed ID: 7630397
[TBL] [Abstract][Full Text] [Related]
20. Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1.
Zhao X; Feng D; Wang Q; Abdulla A; Xie XJ; Zhou J; Sun Y; Yang ES; Liu LP; Vaitheesvaran B; Bridges L; Kurland IJ; Strich R; Ni JQ; Wang C; Ericsson J; Pessin JE; Ji JY; Yang F
J Clin Invest; 2012 Jul; 122(7):2417-27. PubMed ID: 22684109
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
