These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 21807360)

  • 1. Climbing STAIRs towards clinical trials with a novel PARP-1 inhibitor for the treatment of ischemic stroke.
    Ford AL; Lee JM
    Brain Res; 2011 Sep; 1410():120-1. PubMed ID: 21807360
    [No Abstract]   [Full Text] [Related]  

  • 2. Poly(ADP-ribosyl)ation and stroke.
    Chiarugi A
    Pharmacol Res; 2005 Jul; 52(1):15-24. PubMed ID: 15911330
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.
    Iwashita A; Tojo N; Matsuura S; Yamazaki S; Kamijo K; Ishida J; Yamamoto H; Hattori K; Matsuoka N; Mutoh S
    J Pharmacol Exp Ther; 2004 Aug; 310(2):425-36. PubMed ID: 15075382
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3. Life or death decisions: the cast of poly(ADP-ribose)polymerase (PARP) as a therapeutic target for brain ischaemia.
    Pellicciari R; Camaioni E; Costantino G
    Prog Med Chem; 2004; 42():125-69. PubMed ID: 15003720
    [No Abstract]   [Full Text] [Related]  

  • 5. Post-ischemic brain damage: targeting PARP-1 within the ischemic neurovascular units as a realistic avenue to stroke treatment.
    Moroni F; Chiarugi A
    FEBS J; 2009 Jan; 276(1):36-45. PubMed ID: 19087198
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage.
    Moroni F
    Curr Opin Pharmacol; 2008 Feb; 8(1):96-103. PubMed ID: 18032109
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury.
    Kauppinen TM; Suh SW; Berman AE; Hamby AM; Swanson RA
    J Cereb Blood Flow Metab; 2009 Apr; 29(4):820-9. PubMed ID: 19190653
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection.
    McCullough LD; Zeng Z; Blizzard KK; Debchoudhury I; Hurn PD
    J Cereb Blood Flow Metab; 2005 Apr; 25(4):502-12. PubMed ID: 15689952
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke.
    Abdelkarim GE; Gertz K; Harms C; Katchanov J; Dirnagl U; Szabó C; Endres M
    Int J Mol Med; 2001 Mar; 7(3):255-60. PubMed ID: 11179503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MP-124, a novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor, ameliorates ischemic brain damage in a non-human primate model.
    Matsuura S; Egi Y; Yuki S; Horikawa T; Satoh H; Akira T
    Brain Res; 2011 Sep; 1410():122-31. PubMed ID: 21741620
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Poly (adp-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma.
    Komjáti K; Besson VC; Szabó C
    Curr Drug Targets CNS Neurol Disord; 2005 Apr; 4(2):179-94. PubMed ID: 15857303
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulatory T cells increase after treatment with poly (ADP-ribose) polymerase-1 inhibitor in ischemic stroke patients.
    Noh MY; Lee WM; Lee SJ; Kim HY; Kim SH; Kim YS
    Int Immunopharmacol; 2018 Jul; 60():104-110. PubMed ID: 29709770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats.
    Nakajima H; Kakui N; Ohkuma K; Ishikawa M; Hasegawa T
    J Pharmacol Exp Ther; 2005 Feb; 312(2):472-81. PubMed ID: 15466246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. Part 4: biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries.
    Ferraris D; Ficco RP; Dain D; Ginski M; Lautar S; Lee-Wisdom K; Liang S; Lin Q; Lu MX; Morgan L; Thomas B; Williams LR; Zhang J; Zhou Y; Kalish VJ
    Bioorg Med Chem; 2003 Aug; 11(17):3695-707. PubMed ID: 12901915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment.
    Ding Y; Zhou Y; Lai Q; Li J; Gordon V; Diaz FG
    Brain Res; 2001 Oct; 915(2):210-7. PubMed ID: 11595210
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prevention of rt-PA induced blood-brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice.
    Teng F; Beray-Berthat V; Coqueran B; Lesbats C; Kuntz M; Palmier B; Garraud M; Bedfert C; Slane N; Bérézowski V; Szeremeta F; Hachani J; Scherman D; Plotkine M; Doan BT; Marchand-Leroux C; Margaill I
    Exp Neurol; 2013 Oct; 248():416-28. PubMed ID: 23876515
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke.
    Komjáti K; Mabley JG; Virág L; Southan GJ; Salzman AL; Szabó C
    Int J Mol Med; 2004 Mar; 13(3):373-82. PubMed ID: 14767566
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A review on PARP1 inhibitors: Pharmacophore modeling, virtual and biological screening studies to identify novel PARP1 inhibitors.
    Singh SS; Sarma JA; Narasu L; Dayam R; Xu S; Neamati N
    Curr Top Med Chem; 2014; 14(17):2020-30. PubMed ID: 25262797
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Post-treatment with an inhibitor of poly(ADP-ribose) polymerase attenuates cerebral damage in focal ischemia.
    Takahashi K; Pieper AA; Croul SE; Zhang J; Snyder SH; Greenberg JH
    Brain Res; 1999 May; 829(1-2):46-54. PubMed ID: 10350529
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mediation of cell death by poly(ADP-ribose) polymerase-1.
    Koh DW; Dawson TM; Dawson VL
    Pharmacol Res; 2005 Jul; 52(1):5-14. PubMed ID: 15911329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.