244 related articles for article (PubMed ID: 21807883)
1. Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.
Pepinsky RB; Shao Z; Ji B; Wang Q; Meng G; Walus L; Lee X; Hu Y; Graff C; Garber E; Meier W; Mi S
J Pharmacol Exp Ther; 2011 Nov; 339(2):519-29. PubMed ID: 21807883
[TBL] [Abstract][Full Text] [Related]
2. Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.
Pepinsky RB; Arndt JW; Quan C; Gao Y; Quintero-Monzon O; Lee X; Mi S
J Pharmacol Exp Ther; 2014 Jul; 350(1):110-23. PubMed ID: 24756303
[TBL] [Abstract][Full Text] [Related]
3. Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site.
Hanf KJM; Arndt JW; Liu Y; Gong BJ; Rushe M; Sopko R; Massol R; Smith B; Gao Y; Dalkilic-Liddle I; Lee X; Mojta S; Shao Z; Mi S; Pepinsky RB
MAbs; 2020; 12(1):1713648. PubMed ID: 31928294
[TBL] [Abstract][Full Text] [Related]
4. Production of a PEGylated Fab' of the anti-LINGO-1 Li33 antibody and assessment of its biochemical and functional properties in vitro and in a rat model of remyelination.
Pepinsky RB; Walus L; Shao Z; Ji B; Gu S; Sun Y; Wen D; Lee X; Wang Q; Garber E; Mi S
Bioconjug Chem; 2011 Feb; 22(2):200-10. PubMed ID: 21254764
[TBL] [Abstract][Full Text] [Related]
5. LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury.
Ji B; Li M; Wu WT; Yick LW; Lee X; Shao Z; Wang J; So KF; McCoy JM; Pepinsky RB; Mi S; Relton JK
Mol Cell Neurosci; 2006 Nov; 33(3):311-20. PubMed ID: 17011208
[TBL] [Abstract][Full Text] [Related]
6. Passive immunization with LINGO-1 polyclonal antiserum afforded neuroprotection and promoted functional recovery in a rat model of spinal cord injury.
Lv J; Xu RX; Jiang XD; Lu X; Ke YQ; Cai YQ; Du MX; Hu C; Zou YX; Qin LS; Zeng YJ
Neuroimmunomodulation; 2010; 17(4):270-8. PubMed ID: 20203533
[TBL] [Abstract][Full Text] [Related]
7. LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in experimental autoimmune encephalomyelitis mice.
Sun JJ; Ren QG; Xu L; Zhang ZJ
Sci Rep; 2015 Sep; 5():14235. PubMed ID: 26383267
[TBL] [Abstract][Full Text] [Related]
8. Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells.
Mi S; Miller RH; Tang W; Lee X; Hu B; Wu W; Zhang Y; Shields CB; Zhang Y; Miklasz S; Shea D; Mason J; Franklin RJ; Ji B; Shao Z; Chédotal A; Bernard F; Roulois A; Xu J; Jung V; Pepinsky B
Ann Neurol; 2009 Mar; 65(3):304-15. PubMed ID: 19334062
[TBL] [Abstract][Full Text] [Related]
9. Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish.
Yin W; Hu B
Exp Neurol; 2014 Jan; 251():72-83. PubMed ID: 24262204
[TBL] [Abstract][Full Text] [Related]
10. LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.
Mi S; Hu B; Hahm K; Luo Y; Kam Hui ES; Yuan Q; Wong WM; Wang L; Su H; Chu TH; Guo J; Zhang W; So KF; Pepinsky B; Shao Z; Graff C; Garber E; Jung V; Wu EX; Wu W
Nat Med; 2007 Oct; 13(10):1228-33. PubMed ID: 17906634
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of LINGO-1 promotes functional recovery after experimental spinal cord demyelination.
Zhang Y; Zhang YP; Pepinsky B; Huang G; Shields LB; Shields CB; Mi S
Exp Neurol; 2015 Apr; 266():68-73. PubMed ID: 25681574
[TBL] [Abstract][Full Text] [Related]
12. Blocking LINGO-1 function promotes retinal ganglion cell survival following ocular hypertension and optic nerve transection.
Fu QL; Hu B; Wu W; Pepinsky RB; Mi S; So KF
Invest Ophthalmol Vis Sci; 2008 Mar; 49(3):975-85. PubMed ID: 18326721
[TBL] [Abstract][Full Text] [Related]
13. Blocking LINGO-1 as a therapy to promote CNS repair: from concept to the clinic.
Mi S; Pepinsky RB; Cadavid D
CNS Drugs; 2013 Jul; 27(7):493-503. PubMed ID: 23681979
[TBL] [Abstract][Full Text] [Related]
14. Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration.
Thorne RG; Pronk GJ; Padmanabhan V; Frey WH
Neuroscience; 2004; 127(2):481-96. PubMed ID: 15262337
[TBL] [Abstract][Full Text] [Related]
15. Lingo-1 inhibited by RNA interference promotes functional recovery of experimental autoimmune encephalomyelitis.
Wang CJ; Qu CQ; Zhang J; Fu PC; Guo SG; Tang RH
Anat Rec (Hoboken); 2014 Dec; 297(12):2356-63. PubMed ID: 25045138
[TBL] [Abstract][Full Text] [Related]
16. LINGO-1 and its role in CNS repair.
Mi S; Sandrock A; Miller RH
Int J Biochem Cell Biol; 2008; 40(10):1971-8. PubMed ID: 18468478
[TBL] [Abstract][Full Text] [Related]
17. The relationship between aquaporin-4 expression and blood-brain and spinal cord barrier permeability following experimental autoimmune encephalomyelitis in the rat.
Huang XN; Wang WZ; Fu J; Wang HB
Anat Rec (Hoboken); 2011 Jan; 294(1):46-54. PubMed ID: 21157915
[TBL] [Abstract][Full Text] [Related]
18. Targeted Inhibition of Leucine-Rich Repeat and Immunoglobulin Domain-Containing Protein 1 in Transplanted Neural Stem Cells Promotes Neuronal Differentiation and Functional Recovery in Rats Subjected to Spinal Cord Injury.
Chen N; Cen JS; Wang J; Qin G; Long L; Wang L; Wei F; Xiang Q; Deng DY; Wan Y
Crit Care Med; 2016 Mar; 44(3):e146-57. PubMed ID: 26491860
[TBL] [Abstract][Full Text] [Related]
19. The promotion of functional recovery and nerve regeneration after spinal cord injury by lentiviral vectors encoding Lingo-1 shRNA delivered by Pluronic F-127.
Wu HF; Cen JS; Zhong Q; Chen L; Wang J; Deng DY; Wan Y
Biomaterials; 2013 Feb; 34(6):1686-700. PubMed ID: 23211450
[TBL] [Abstract][Full Text] [Related]
20. The distribution of inflammatory demyelinated lesions in the central nervous system of rats with antibody-augmented demyelinating experimental allergic encephalomyelitis.
Meeson AP; Piddlesden S; Morgan BP; Reynolds R
Exp Neurol; 1994 Oct; 129(2):299-310. PubMed ID: 7525334
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
