BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 21813340)

  • 1. Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.
    Kim N; Jinks-Robertson S
    DNA Repair (Amst); 2011 Sep; 10(9):953-60. PubMed ID: 21813340
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of topoisomerase I in suppressing genome instability associated with a highly transcribed guanine-rich sequence is not restricted to preventing RNA:DNA hybrid accumulation.
    Yadav P; Owiti N; Kim N
    Nucleic Acids Res; 2016 Jan; 44(2):718-29. PubMed ID: 26527723
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Topoisomerase I plays a critical role in suppressing genome instability at a highly transcribed G-quadruplex-forming sequence.
    Yadav P; Harcy V; Argueso JL; Dominska M; Jinks-Robertson S; Kim N
    PLoS Genet; 2014 Dec; 10(12):e1004839. PubMed ID: 25473964
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA.
    Lopez CR; Singh S; Hambarde S; Griffin WC; Gao J; Chib S; Yu Y; Ira G; Raney KD; Kim N
    Nucleic Acids Res; 2017 Jun; 45(10):5850-5862. PubMed ID: 28369605
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.
    Ruiz JF; Gómez-González B; Aguilera A
    PLoS Genet; 2011 Feb; 7(2):e1002009. PubMed ID: 21383964
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.
    Kobayashi M; Aida M; Nagaoka H; Begum NA; Kitawaki Y; Nakata M; Stanlie A; Doi T; Kato L; Okazaki IM; Shinkura R; Muramatsu M; Kinoshita K; Honjo T
    Proc Natl Acad Sci U S A; 2009 Dec; 106(52):22375-80. PubMed ID: 20018730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The repetitive portion of the Xenopus IgH Mu switch region mediates orientation-dependent class switch recombination.
    Zhang ZZ; Pannunzio NR; Lu Z; Hsu E; Yu K; Lieber MR
    Mol Immunol; 2015 Oct; 67(2 Pt B):524-31. PubMed ID: 26277278
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region.
    Huang FT; Yu K; Balter BB; Selsing E; Oruc Z; Khamlichi AA; Hsieh CL; Lieber MR
    Mol Cell Biol; 2007 Aug; 27(16):5921-32. PubMed ID: 17562862
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability.
    Husain A; Begum NA; Taniguchi T; Taniguchi H; Kobayashi M; Honjo T
    Nat Commun; 2016 Feb; 7():10549. PubMed ID: 26842758
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Interplay between G-quadruplex and Transcription.
    Kim N
    Curr Med Chem; 2019; 26(16):2898-2917. PubMed ID: 29284393
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation.
    Kobayashi M; Sabouri Z; Sabouri S; Kitawaki Y; Pommier Y; Abe T; Kiyonari H; Honjo T
    Proc Natl Acad Sci U S A; 2011 Nov; 108(48):19305-10. PubMed ID: 22080610
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of homologous recombination between sequence repeats by the activation induced cytidine deaminase (AID) protein.
    Buerstedde JM; Lowndes N; Schatz DG
    Elife; 2014 Jul; 3():e03110. PubMed ID: 25006166
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.
    Mullen JR; Nallaseth FS; Lan YQ; Slagle CE; Brill SJ
    Mol Cell Biol; 2005 Jun; 25(11):4476-87. PubMed ID: 15899853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Yeast Nucleolin Nsr1 Impedes Replication and Elevates Genome Instability at an Actively Transcribed Guanine-Rich G4 DNA-Forming Sequence.
    Singh S; Berroyer A; Kim M; Kim N
    Genetics; 2020 Dec; 216(4):1023-1037. PubMed ID: 33106247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation.
    Rajagopal D; Maul RW; Ghosh A; Chakraborty T; Khamlichi AA; Sen R; Gearhart PJ
    J Exp Med; 2009 Jun; 206(6):1237-44. PubMed ID: 19433618
    [TBL] [Abstract][Full Text] [Related]  

  • 16. G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA polymerase II.
    Tornaletti S; Park-Snyder S; Hanawalt PC
    J Biol Chem; 2008 May; 283(19):12756-62. PubMed ID: 18292094
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Topoisomerase I and Genome Stability: The Good and the Bad.
    Cho JE; Jinks-Robertson S
    Methods Mol Biol; 2018; 1703():21-45. PubMed ID: 29177731
    [TBL] [Abstract][Full Text] [Related]  

  • 18. R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching.
    Maul RW; Chon H; Sakhuja K; Cerritelli SM; Gugliotti LA; Gearhart PJ; Crouch RJ
    J Mol Biol; 2017 Oct; 429(21):3255-3263. PubMed ID: 28065739
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo.
    Ribeyre C; Lopes J; Boulé JB; Piazza A; Guédin A; Zakian VA; Mergny JL; Nicolas A
    PLoS Genet; 2009 May; 5(5):e1000475. PubMed ID: 19424434
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.
    Kadungure T; Ucher AJ; Linehan EK; Schrader CE; Stavnezer J
    PLoS One; 2015; 10(8):e0134397. PubMed ID: 26267846
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.