BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 21813464)

  • 21. Differential regulation of redox responsive transcription factors by the nephrocarcinogen 2,3,5-Tris(glutathion-S-yl)hydroquinone.
    Weber TJ; Huang Q; Monks TJ; Lau SS
    Chem Res Toxicol; 2001 Jul; 14(7):814-21. PubMed ID: 11453727
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model.
    Sahin K; Cross B; Sahin N; Ciccone K; Suleiman S; Osunkoya AO; Master V; Harris W; Carthon B; Mohammad R; Bilir B; Wertz K; Moreno CS; Walker CL; Kucuk O
    Arch Biochem Biophys; 2015 Apr; 572():36-39. PubMed ID: 25602702
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
    Palaniappan M; Menon KM
    Mol Endocrinol; 2010 Sep; 24(9):1782-93. PubMed ID: 20660299
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model.
    Mi R; Ma J; Zhang D; Li L; Zhang H
    J Genet Genomics; 2009 Jun; 36(6):355-61. PubMed ID: 19539245
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
    Hahn M; Li W; Yu C; Rahmani M; Dent P; Grant S
    Mol Cancer Ther; 2005 Mar; 4(3):457-70. PubMed ID: 15767555
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells.
    Calipel A; Mouriaux F; Glotin AL; Malecaze F; Faussat AM; Mascarelli F
    J Biol Chem; 2006 Apr; 281(14):9238-50. PubMed ID: 16452469
    [TBL] [Abstract][Full Text] [Related]  

  • 27. FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells.
    Abel EV; Aplin AE
    Cancer Res; 2010 Apr; 70(7):2891-900. PubMed ID: 20332228
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion.
    Cheepala SB; Yin W; Syed Z; Gill JN; McMillian A; Kleiner HE; Lynch M; Loganantharaj R; Trutschl M; Cvek U; Clifford JL
    Mol Cancer; 2009 May; 8():27. PubMed ID: 19432991
    [TBL] [Abstract][Full Text] [Related]  

  • 29. PIK3CA mutation uncouples tumor growth and cyclin D1 regulation from MEK/ERK and mutant KRAS signaling.
    Halilovic E; She QB; Ye Q; Pagliarini R; Sellers WR; Solit DB; Rosen N
    Cancer Res; 2010 Sep; 70(17):6804-14. PubMed ID: 20699365
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Sp1 regulates Raf/MEK/ERK-induced p21(CIP1) transcription in TP53-mutated cancer cells.
    Karkhanis M; Park JI
    Cell Signal; 2015 Mar; 27(3):479-86. PubMed ID: 25595558
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models.
    Lee N; Woodrum CL; Nobil AM; Rauktys AE; Messina MP; Dabora SL
    BMC Pharmacol; 2009 Apr; 9():8. PubMed ID: 19368729
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
    Ikenoue T; Hikiba Y; Kanai F; Aragaki J; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2004 May; 64(10):3428-35. PubMed ID: 15150094
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.
    Gysin S; Lee SH; Dean NM; McMahon M
    Cancer Res; 2005 Jun; 65(11):4870-80. PubMed ID: 15930308
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Sorafenib inhibits non-small cell lung cancer cell growth by targeting B-RAF in KRAS wild-type cells and C-RAF in KRAS mutant cells.
    Takezawa K; Okamoto I; Yonesaka K; Hatashita E; Yamada Y; Fukuoka M; Nakagawa K
    Cancer Res; 2009 Aug; 69(16):6515-21. PubMed ID: 19638574
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin.
    Tee AR; Anjum R; Blenis J
    J Biol Chem; 2003 Sep; 278(39):37288-96. PubMed ID: 12867426
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors.
    Habib SL; Simone S; Barnes JJ; Abboud HE
    Mol Cancer; 2008 Jan; 7():10. PubMed ID: 18218111
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.
    Akbulut T; Regner KR; Roman RJ; Avner ED; Falck JR; Park F
    Am J Physiol Renal Physiol; 2009 Sep; 297(3):F662-70. PubMed ID: 19570883
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease.
    Nagao S; Yamaguchi T; Kusaka M; Maser RL; Takahashi H; Cowley BD; Grantham JJ
    Kidney Int; 2003 Feb; 63(2):427-37. PubMed ID: 12631108
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation.
    Hecquet C; Lefevre G; Valtink M; Engelmann K; Mascarelli F
    Invest Ophthalmol Vis Sci; 2002 Sep; 43(9):3091-8. PubMed ID: 12202534
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Immunochemical analysis of quinol-thioether-derived covalent protein adducts in rodent species sensitive and resistant to quinol-thioether-mediated nephrotoxicity.
    Kleiner HE; Jones TW; Monks TJ; Lau SS
    Chem Res Toxicol; 1998 Nov; 11(11):1291-300. PubMed ID: 9815189
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.