BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 21814043)

  • 1. The p75NTR extracellular domain: a potential molecule regulating the solubility and removal of amyloid-β.
    Zhou XF; Wang YJ
    Prion; 2011; 5(3):161-3. PubMed ID: 21814043
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cysteine-Rich Repeat Domains 2 and 4 are Amyloid-β Binding Domains of Neurotrophin Receptor p75NTR and Potential Targets to Block Amyloid-β Neurotoxicity.
    Wang YR; Wang J; Liu YH; Hu GL; Gao CY; Wang YJ; Zhou XF; Zeng F
    J Alzheimers Dis; 2018; 63(1):139-147. PubMed ID: 29578485
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intramuscular delivery of p75NTR ectodomain by an AAV vector attenuates cognitive deficits and Alzheimer's disease-like pathologies in APP/PS1 transgenic mice.
    Wang QH; Wang YR; Zhang T; Jiao SS; Liu YH; Zeng F; Li J; Yao XQ; Zhou HD; Zhou XF; Wang YJ
    J Neurochem; 2016 Jul; 138(1):163-73. PubMed ID: 26991827
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.
    Yang F; Lim GP; Begum AN; Ubeda OJ; Simmons MR; Ambegaokar SS; Chen PP; Kayed R; Glabe CG; Frautschy SA; Cole GM
    J Biol Chem; 2005 Feb; 280(7):5892-901. PubMed ID: 15590663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model.
    Qosa H; LeVine H; Keller JN; Kaddoumi A
    Biochim Biophys Acta; 2014 Sep; 1842(9):1806-15. PubMed ID: 24997450
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain.
    Wang YJ; Wang X; Lu JJ; Li QX; Gao CY; Liu XH; Sun Y; Yang M; Lim Y; Evin G; Zhong JH; Masters C; Zhou XF
    J Neurosci; 2011 Feb; 31(6):2292-304. PubMed ID: 21307265
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyloid binding ligands as Alzheimer's disease therapies.
    Lee VM
    Neurobiol Aging; 2002; 23(6):1039-42. PubMed ID: 12470800
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alternate aggregation pathways of the Alzheimer beta-amyloid peptide. An in vitro model of preamyloid.
    Huang TH; Yang DS; Fraser PE; Chakrabartty A
    J Biol Chem; 2000 Nov; 275(46):36436-40. PubMed ID: 10961999
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [The pathophysiology of Alzheimer's disease with special reference to "amyloid cascade hypothesis"].
    Tamaoka A
    Rinsho Byori; 2013 Nov; 61(11):1060-9. PubMed ID: 24450113
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Detection of amyloid plaques by radioligands for Abeta40 and Abeta42: potential imaging agents in Alzheimer's patients.
    Kung MP; Skovronsky DM; Hou C; Zhuang ZP; Gur TL; Zhang B; Trojanowski JQ; Lee VM; Kung HF
    J Mol Neurosci; 2003 Feb; 20(1):15-24. PubMed ID: 12663930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The antibody aducanumab reduces Aβ plaques in Alzheimer's disease.
    Sevigny J; Chiao P; Bussière T; Weinreb PH; Williams L; Maier M; Dunstan R; Salloway S; Chen T; Ling Y; O'Gorman J; Qian F; Arastu M; Li M; Chollate S; Brennan MS; Quintero-Monzon O; Scannevin RH; Arnold HM; Engber T; Rhodes K; Ferrero J; Hang Y; Mikulskis A; Grimm J; Hock C; Nitsch RM; Sandrock A
    Nature; 2016 Sep; 537(7618):50-6. PubMed ID: 27582220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease.
    Verdier Y; Zarándi M; Penke B
    J Pept Sci; 2004 May; 10(5):229-48. PubMed ID: 15160835
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging.
    Costantini C; Weindruch R; Della Valle G; Puglielli L
    Biochem J; 2005 Oct; 391(Pt 1):59-67. PubMed ID: 15966860
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.
    Simmons DA; Knowles JK; Belichenko NP; Banerjee G; Finkle C; Massa SM; Longo FM
    PLoS One; 2014; 9(8):e102136. PubMed ID: 25153701
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model.
    Baik SH; Kang S; Son SM; Mook-Jung I
    Glia; 2016 Dec; 64(12):2274-2290. PubMed ID: 27658617
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD.
    Hashimoto Y; Kaneko Y; Tsukamoto E; Frankowski H; Kouyama K; Kita Y; Niikura T; Aiso S; Bredesen DE; Matsuoka M; Nishimoto I
    J Neurochem; 2004 Aug; 90(3):549-58. PubMed ID: 15255932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ongoing search for small molecules to study metal-associated amyloid-β species in Alzheimer's disease.
    Savelieff MG; DeToma AS; Derrick JS; Lim MH
    Acc Chem Res; 2014 Aug; 47(8):2475-82. PubMed ID: 25080056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer's disease.
    Park S; Kim HY; Oh HA; Shin J; Park IW; Yoon S; Woo DH; Kim Y
    Sci Rep; 2021 Jun; 11(1):12043. PubMed ID: 34103615
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Accumulation of cellular prion protein within dystrophic neurites of amyloid plaques in the Alzheimer's disease brain.
    Takahashi RH; Tobiume M; Sato Y; Sata T; Gouras GK; Takahashi H
    Neuropathology; 2011 Jun; 31(3):208-14. PubMed ID: 21062360
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B; Crawford F; Bachmeier C
    Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.