BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 21819973)

  • 1. Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells.
    Park HS; Jun do Y; Han CR; Woo HJ; Kim YH
    Biochem Pharmacol; 2011 Nov; 82(9):1110-25. PubMed ID: 21819973
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL.
    Kim SM; Park HS; Jun DY; Woo HJ; Woo MH; Yang CH; Kim YH
    Toxicol Appl Pharmacol; 2009 Dec; 241(2):210-20. PubMed ID: 19716835
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein tyrosine kinase p56lck-deficiency confers hypersusceptibility to rho-fluorophenylalanine (pFPhe)-induced apoptosis by augmenting mitochondrial apoptotic pathway in human Jurkat T cells.
    Park HS; Jun DY; Han CR; Kim YH
    Biochem Biophys Res Commun; 2008 Dec; 377(1):280-5. PubMed ID: 18845126
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of tyrosine kinase p56/Lck in apoptosis induction by anticancer drugs.
    Gruber C; Henkel M; Budach W; Belka C; Jendrossek V
    Biochem Pharmacol; 2004 May; 67(10):1859-72. PubMed ID: 15130763
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Capsaicin-induced apoptosis is regulated by endoplasmic reticulum stress- and calpain-mediated mitochondrial cell death pathways.
    Lee MJ; Kee KH; Suh CH; Lim SC; Oh SH
    Toxicology; 2009 Oct; 264(3):205-14. PubMed ID: 19699254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptogenic activity of auraptene of Zanthoxylum schinifolium toward human acute leukemia Jurkat T cells is associated with ER stress-mediated caspase-8 activation that stimulates mitochondria-dependent or -independent caspase cascade.
    Jun DY; Kim JS; Park HS; Han CR; Fang Z; Woo MH; Rhee IK; Kim YH
    Carcinogenesis; 2007 Jun; 28(6):1303-13. PubMed ID: 17301064
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Apoptogenic activity of 2α,3α-dihydroxyurs-12-ene-28-oic acid from Prunella vulgaris var. lilacina is mediated via mitochondria-dependent activation of caspase cascade regulated by Bcl-2 in human acute leukemia Jurkat T cells.
    Woo HJ; Jun do Y; Lee JY; Woo MH; Yang CH; Kim YH
    J Ethnopharmacol; 2011 Jun; 135(3):626-35. PubMed ID: 21473903
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kaempferol Activates G₂-Checkpoint of the Cell Cycle Resulting in G₂-Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells.
    Kim KY; Jang WY; Lee JY; Jun do Y; Ko JY; Yun YH; Kim YH
    J Microbiol Biotechnol; 2016 Feb; 26(2):287-94. PubMed ID: 26699757
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways.
    Belka C; Gruber C; Jendrossek V; Wesselborg S; Budach W
    Oncogene; 2003 Jan; 22(2):176-85. PubMed ID: 12527887
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein tyrosine kinase p56lck is required for ceramide-induced but not tumor necrosis factor-induced activation of NF-kappa B, AP-1, JNK, and apoptosis.
    Manna SK; Sah NK; Aggarwal BB
    J Biol Chem; 2000 May; 275(18):13297-306. PubMed ID: 10788436
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression.
    Samraj AK; Stroh C; Fischer U; Schulze-Osthoff K
    Oncogene; 2006 Jan; 25(2):186-97. PubMed ID: 16116473
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells.
    Jun DY; Kim JS; Park HS; Song WS; Bae YS; Kim YH
    Toxicol Appl Pharmacol; 2007 Jul; 222(2):190-201. PubMed ID: 17559898
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death.
    Kim MJ; Park MT; Yoon CH; Byun JY; Lee SJ
    Biochem Biophys Res Commun; 2008 May; 370(2):353-8. PubMed ID: 18371298
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rosmarinic acid induces p56lck-dependent apoptosis in Jurkat and peripheral T cells via mitochondrial pathway independent from Fas/Fas ligand interaction.
    Hur YG; Yun Y; Won J
    J Immunol; 2004 Jan; 172(1):79-87. PubMed ID: 14688312
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential requirement for p56lck in HIV-tat versus TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal kinase, and apoptosis.
    Manna SK; Aggarwal BB
    J Immunol; 2000 May; 164(10):5156-66. PubMed ID: 10799874
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The additional loss of Bak and not the lack of the protein tyrosine kinase p56/Lck in one JCaM1.6 subclone caused pronounced apoptosis resistance in response to stimuli of the intrinsic pathway.
    Rudner J; Mueller AC; Matzner N; Huber SM; Handrick R; Belka C; Jendrossek V
    Apoptosis; 2009 May; 14(5):711-20. PubMed ID: 19343496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-XS and activation of caspase-3.
    Emanuele S; Calvaruso G; Lauricella M; Giuliano M; Bellavia G; D'Anneo A; Vento R; Tesoriere G
    Int J Oncol; 2002 Oct; 21(4):857-65. PubMed ID: 12239627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR; Jun do Y; Lee JY; Kim YH
    Apoptosis; 2014 Jan; 19(1):224-40. PubMed ID: 24166139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prometaphase arrest-dependent phosphorylation of Bcl-2 family proteins and activation of mitochondrial apoptotic pathway are associated with 17α-estradiol-induced apoptosis in human Jurkat T cells.
    Han CR; Jun do Y; Kim YH; Lee JY; Kim YH
    Biochim Biophys Acta; 2013 Oct; 1833(10):2220-32. PubMed ID: 23707954
    [TBL] [Abstract][Full Text] [Related]  

  • 20. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    MacFarlane M; Cohen GM; Dickens M
    Biochem J; 2000 May; 348 Pt 1(Pt 1):93-101. PubMed ID: 10794718
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.