114 related articles for article (PubMed ID: 2182010)
21. A hydrogen-bonding network modulating enzyme function: asparagine-194 and tyrosine-225 of Escherichia coli aspartate aminotransferase.
Yano T; Mizuno T; Kagamiyama H
Biochemistry; 1993 Feb; 32(7):1810-5. PubMed ID: 8439541
[TBL] [Abstract][Full Text] [Related]
22. Site-directed mutagenesis of Escherichia coli aspartate aminotransferase: role of Tyr70 in the catalytic processes.
Inoue K; Kuramitsu S; Okamoto A; Hirotsu K; Higuchi T; Kagamiyama H
Biochemistry; 1991 Aug; 30(31):7796-801. PubMed ID: 1868057
[TBL] [Abstract][Full Text] [Related]
23. Nonidentity of the aspartate and the aromatic aminotransferase components of transaminase A in Escherichia coli.
Collier RH; Kohlhaw G
J Bacteriol; 1972 Oct; 112(1):365-71. PubMed ID: 4404056
[TBL] [Abstract][Full Text] [Related]
24. Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis.
Hayashi H; Mizuguchi H; Miyahara I; Nakajima Y; Hirotsu K; Kagamiyama H
J Biol Chem; 2003 Mar; 278(11):9481-8. PubMed ID: 12488449
[TBL] [Abstract][Full Text] [Related]
25. Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli.
Mavrides C; Orr W
J Biol Chem; 1975 Jun; 250(11):4128-33. PubMed ID: 236311
[TBL] [Abstract][Full Text] [Related]
26. Effects of the phenylalanine-22----leucine, glutamic acid-49----methionine, glycine-234----aspartic acid, and glycine-234----lysine mutations on the folding and stability of the alpha subunit of tryptophan synthase from Escherichia coli.
Beasty AM; Hurle MR; Manz JT; Stackhouse T; Onuffer JJ; Matthews CR
Biochemistry; 1986 May; 25(10):2965-74. PubMed ID: 2872918
[TBL] [Abstract][Full Text] [Related]
27. Significant improvement to the catalytic properties of aspartate aminotransferase: role of hydrophobic and charged residues in the substrate binding pocket.
Köhler E; Seville M; Jäger J; Fotheringham I; Hunter M; Edwards M; Jansonius JN; Kirschner K
Biochemistry; 1994 Jan; 33(1):90-7. PubMed ID: 7904477
[TBL] [Abstract][Full Text] [Related]
28. Characterization of the apparent negative co-operativity induced in Escherichia coli aspartate aminotransferase by the replacement of Asp222 with alanine. Evidence for an extremely slow conformational change.
Onuffer JJ; Kirsch JF
Protein Eng; 1994 Mar; 7(3):413-24. PubMed ID: 8177890
[TBL] [Abstract][Full Text] [Related]
29. Analysis of the substrate-recognition mode of aromatic amino acid aminotransferase by combined use of quasisubstrates and site-directed mutagenesis: systematic hydroxy-group addition/deletion studies to probe the enzyme-substrate interactions.
Hayashi H; Inoue K; Mizuguchi H; Kagamiyama H
Biochemistry; 1996 May; 35(21):6754-61. PubMed ID: 8639626
[TBL] [Abstract][Full Text] [Related]
30. Use of site-directed mutagenesis and alternative substrates to assign the prototropic groups important to catalysis by Escherichia coli aspartate aminotransferase.
Gloss LM; Kirsch JF
Biochemistry; 1995 Mar; 34(12):3999-4007. PubMed ID: 7696265
[TBL] [Abstract][Full Text] [Related]
31. 2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli.
Smith DL; Almo SC; Toney MD; Ringe D
Biochemistry; 1989 Oct; 28(20):8161-7. PubMed ID: 2513875
[TBL] [Abstract][Full Text] [Related]
32. Construction of aminotransferase chimeras and analysis of their substrate specificity.
Miyazawa K; Kawaguchi S; Okamoto A; Kato R; Ogawa T; Kuramitsu S
J Biochem; 1994 Mar; 115(3):568-77. PubMed ID: 8056774
[TBL] [Abstract][Full Text] [Related]
33. Contribution to catalysis and stability of the five cysteines in Escherichia coli aspartate aminotransferase. Preparation and properties of a cysteine-free enzyme.
Gloss LM; Planas A; Kirsch JF
Biochemistry; 1992 Jan; 31(1):32-9. PubMed ID: 1731883
[TBL] [Abstract][Full Text] [Related]
34. Examining the structural and chemical flexibility of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with unnatural amino acids.
Gloss LM; Kirsch JF
Biochemistry; 1995 Sep; 34(38):12323-32. PubMed ID: 7547975
[TBL] [Abstract][Full Text] [Related]
35. Escherichia coli mutants deficient in the aspartate and aromatic amino acid aminotransferases.
Gelfand DH; Steinberg RA
J Bacteriol; 1977 Apr; 130(1):429-40. PubMed ID: 15983
[TBL] [Abstract][Full Text] [Related]
36. Analysis of wild-type and mutant aspartate aminotransferases using integrated rate equations.
Schiller MR; Holmes LD; Boeker EA
Biochim Biophys Acta; 1996 Sep; 1297(1):17-27. PubMed ID: 8841376
[TBL] [Abstract][Full Text] [Related]
37. Substitution of an arginyl residue for the active site lysyl residue (Lys258) of aspartate aminotransferase.
Kuramitsu S; Inoue Y; Tanase S; Morino Y; Kagamiyama H
Biochem Biophys Res Commun; 1987 Jul; 146(2):416-21. PubMed ID: 3113421
[TBL] [Abstract][Full Text] [Related]
38. Role of arginine-292 in the substrate specificity of aspartate aminotransferase as examined by site-directed mutagenesis.
Cronin CN; Kirsch JF
Biochemistry; 1988 Jun; 27(12):4572-9. PubMed ID: 3167000
[TBL] [Abstract][Full Text] [Related]
39. Directed evolution of an aspartate aminotransferase with new substrate specificities.
Yano T; Oue S; Kagamiyama H
Proc Natl Acad Sci U S A; 1998 May; 95(10):5511-5. PubMed ID: 9576913
[TBL] [Abstract][Full Text] [Related]
40. Paracoccus denitrificans aromatic amino acid aminotransferase: a model enzyme for the study of dual substrate recognition mechanism.
Oue S; Okamoto A; Nakai Y; Nakahira M; Shibatani T; Hayashi H; Kagamiyama H
J Biochem; 1997 Jan; 121(1):161-71. PubMed ID: 9058208
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]