316 related articles for article (PubMed ID: 21820372)
1. Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs.
Toledo LI; Murga M; Fernandez-Capetillo O
Mol Oncol; 2011 Aug; 5(4):368-73. PubMed ID: 21820372
[TBL] [Abstract][Full Text] [Related]
2. Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.
Palii SS; Cui Y; Innes CL; Paules RS
Cell Cycle; 2013 Apr; 12(7):1105-18. PubMed ID: 23462183
[TBL] [Abstract][Full Text] [Related]
3. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.
Pabla N; Huang S; Mi QS; Daniel R; Dong Z
J Biol Chem; 2008 Mar; 283(10):6572-83. PubMed ID: 18162465
[TBL] [Abstract][Full Text] [Related]
4. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
[TBL] [Abstract][Full Text] [Related]
5. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.
Helt CE; Cliby WA; Keng PC; Bambara RA; O'Reilly MA
J Biol Chem; 2005 Jan; 280(2):1186-92. PubMed ID: 15533933
[TBL] [Abstract][Full Text] [Related]
6. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
Demidova AR; Aau MY; Zhuang L; Yu Q
J Biol Chem; 2009 Feb; 284(7):4132-9. PubMed ID: 19060337
[TBL] [Abstract][Full Text] [Related]
7. Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase.
Lindsey-Boltz LA; Serçin O; Choi JH; Sancar A
J Biol Chem; 2009 Nov; 284(48):33107-14. PubMed ID: 19828454
[TBL] [Abstract][Full Text] [Related]
8. UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway.
Warmerdam DO; Brinkman EK; Marteijn JA; Medema RH; Kanaar R; Smits VA
J Cell Sci; 2013 May; 126(Pt 9):1923-30. PubMed ID: 23447674
[TBL] [Abstract][Full Text] [Related]
9. Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites.
Das KC; Dashnamoorthy R
Am J Physiol Lung Cell Mol Physiol; 2004 Jan; 286(1):L87-97. PubMed ID: 12959929
[TBL] [Abstract][Full Text] [Related]
10. Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity.
Kawasumi M; Bradner JE; Tolliday N; Thibodeau R; Sloan H; Brummond KM; Nghiem P
Cancer Res; 2014 Dec; 74(24):7534-45. PubMed ID: 25336189
[TBL] [Abstract][Full Text] [Related]
11. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.
Smith J; Tho LM; Xu N; Gillespie DA
Adv Cancer Res; 2010; 108():73-112. PubMed ID: 21034966
[TBL] [Abstract][Full Text] [Related]
12. 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.
Chaudhary P; Sharma R; Sahu M; Vishwanatha JK; Awasthi S; Awasthi YC
J Biol Chem; 2013 Jul; 288(28):20532-46. PubMed ID: 23733185
[TBL] [Abstract][Full Text] [Related]
13. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.
Lee HJ; Hwang HI; Jang YJ
Cell Cycle; 2010 Jun; 9(12):2389-98. PubMed ID: 20581453
[TBL] [Abstract][Full Text] [Related]
14. Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells.
Wilsker D; Chung JH; Bunz F
Cell Cycle; 2012 Apr; 11(8):1564-72. PubMed ID: 22433954
[TBL] [Abstract][Full Text] [Related]
15. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
Pan Y; Ren KH; He HW; Shao RG
Cancer Biol Ther; 2009 Aug; 8(16):1559-66. PubMed ID: 19502782
[TBL] [Abstract][Full Text] [Related]
16. Ultrasound activates ataxia telangiectasia mutated- and rad3-related (ATR)-checkpoint kinase 1 (Chk1) pathway in human leukemia Jurkat cells.
Furusawa Y; Iizumi T; Fujiwara Y; Hassan MA; Tabuchi Y; Nomura T; Kondo T
Ultrason Sonochem; 2012 Nov; 19(6):1246-51. PubMed ID: 22571845
[TBL] [Abstract][Full Text] [Related]
17. ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.
Myers K; Gagou ME; Zuazua-Villar P; Rodriguez R; Meuth M
PLoS Genet; 2009 Jan; 5(1):e1000324. PubMed ID: 19119425
[TBL] [Abstract][Full Text] [Related]
18. ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine.
Heffernan TP; Kawasumi M; Blasina A; Anderes K; Conney AH; Nghiem P
J Invest Dermatol; 2009 Jul; 129(7):1805-15. PubMed ID: 19242509
[TBL] [Abstract][Full Text] [Related]
19. Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor.
Rocha S; Garrett MD; Campbell KJ; Schumm K; Perkins ND
EMBO J; 2005 Mar; 24(6):1157-69. PubMed ID: 15775976
[TBL] [Abstract][Full Text] [Related]
20. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.
Liu Q; Guntuku S; Cui XS; Matsuoka S; Cortez D; Tamai K; Luo G; Carattini-Rivera S; DeMayo F; Bradley A; Donehower LA; Elledge SJ
Genes Dev; 2000 Jun; 14(12):1448-59. PubMed ID: 10859164
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]