BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 21820404)

  • 1. Crystal structure of the mismatch-specific thymine glycosylase domain of human methyl-CpG-binding protein MBD4.
    Zhang W; Liu Z; Crombet L; Amaya MF; Liu Y; Zhang X; Kuang W; Ma P; Niu L; Qi C
    Biochem Biophys Res Commun; 2011 Sep; 412(3):425-8. PubMed ID: 21820404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4.
    Wu P; Qiu C; Sohail A; Zhang X; Bhagwat AS; Cheng X
    J Biol Chem; 2003 Feb; 278(7):5285-91. PubMed ID: 12456671
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain.
    Petronzelli F; Riccio A; Markham GD; Seeholzer SH; Genuardi M; Karbowski M; Yeung AT; Matsumoto Y; Bellacosa A
    J Cell Physiol; 2000 Dec; 185(3):473-80. PubMed ID: 11056019
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.
    Mol CD; Arvai AS; Begley TJ; Cunningham RP; Tainer JA
    J Mol Biol; 2002 Jan; 315(3):373-84. PubMed ID: 11786018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4.
    Ouzon-Shubeita H; Jung H; Lee MH; Koag MC; Lee S
    Biochem J; 2020 May; 477(9):1601-1612. PubMed ID: 32297632
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA.
    Moréra S; Grin I; Vigouroux A; Couvé S; Henriot V; Saparbaev M; Ishchenko AA
    Nucleic Acids Res; 2012 Oct; 40(19):9917-26. PubMed ID: 22848106
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation.
    Hashimoto H; Zhang X; Cheng X
    Nucleic Acids Res; 2012 Sep; 40(17):8276-84. PubMed ID: 22740654
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.
    Manvilla BA; Maiti A; Begley MC; Toth EA; Drohat AC
    J Mol Biol; 2012 Jul; 420(3):164-75. PubMed ID: 22560993
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity.
    Pelletier H; Sawaya MR; Wolfle W; Wilson SH; Kraut J
    Biochemistry; 1996 Oct; 35(39):12742-61. PubMed ID: 8841118
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The thymine-DNA glycosylase regulatory domain: residual structure and DNA binding.
    Smet-Nocca C; Wieruszeski JM; Chaar V; Leroy A; Benecke A
    Biochemistry; 2008 Jun; 47(25):6519-30. PubMed ID: 18512959
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular characterization of a putative plant homolog of MBD4 DNA glycosylase.
    Ramiro-Merina Á; Ariza RR; Roldán-Arjona T
    DNA Repair (Amst); 2013 Nov; 12(11):890-8. PubMed ID: 23994068
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into the substrate discrimination mechanisms of methyl-CpG-binding domain 4.
    Ouzon-Shubeita H; Schmaltz LF; Lee S
    Biochem J; 2021 May; 478(10):1985-1997. PubMed ID: 33960375
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites.
    Hendrich B; Hardeland U; Ng HH; Jiricny J; Bird A
    Nature; 1999 Sep; 401(6750):301-4. PubMed ID: 10499592
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence.
    Zhu B; Zheng Y; Angliker H; Schwarz S; Thiry S; Siegmann M; Jost JP
    Nucleic Acids Res; 2000 Nov; 28(21):4157-65. PubMed ID: 11058112
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural Insights into the Mechanism of Base Excision by MBD4.
    Pidugu LS; Bright H; Lin WJ; Majumdar C; Van Ostrand RP; David SS; Pozharski E; Drohat AC
    J Mol Biol; 2021 Jul; 433(15):167097. PubMed ID: 34107280
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of thymine DNA glycosylase conjugated to SUMO-1.
    Baba D; Maita N; Jee JG; Uchimura Y; Saitoh H; Sugasawa K; Hanaoka F; Tochio H; Hiroaki H; Shirakawa M
    Nature; 2005 Jun; 435(7044):979-82. PubMed ID: 15959518
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Solution structure and intramolecular exchange of methyl-cytosine binding domain protein 4 (MBD4) on DNA suggests a mechanism to scan for mCpG/TpG mismatches.
    Walavalkar NM; Cramer JM; Buchwald WA; Scarsdale JN; Williams DC
    Nucleic Acids Res; 2014; 42(17):11218-32. PubMed ID: 25183517
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of a thwarted mismatch glycosylase DNA repair complex.
    Barrett TE; Schärer OD; Savva R; Brown T; Jiricny J; Verdine GL; Pearl LH
    EMBO J; 1999 Dec; 18(23):6599-609. PubMed ID: 10581234
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of an archaeal intein-encoded homing endonuclease PI-PfuI.
    Ichiyanagi K; Ishino Y; Ariyoshi M; Komori K; Morikawa K
    J Mol Biol; 2000 Jul; 300(4):889-901. PubMed ID: 10891276
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites.
    Bellacosa A; Drohat AC
    DNA Repair (Amst); 2015 Aug; 32():33-42. PubMed ID: 26021671
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.