292 related articles for article (PubMed ID: 21820422)
1. Triptolide, histone acetyltransferase inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway.
Park B; Sung B; Yadav VR; Chaturvedi MM; Aggarwal BB
Biochem Pharmacol; 2011 Nov; 82(9):1134-44. PubMed ID: 21820422
[TBL] [Abstract][Full Text] [Related]
2. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
Takada Y; Kobayashi Y; Aggarwal BB
J Biol Chem; 2005 Apr; 280(17):17203-12. PubMed ID: 15710601
[TBL] [Abstract][Full Text] [Related]
3. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
Sung B; Pandey MK; Aggarwal BB
Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
[TBL] [Abstract][Full Text] [Related]
4. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
[TBL] [Abstract][Full Text] [Related]
5. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
Kunnumakkara AB; Ichikawa H; Anand P; Mohankumar CJ; Hema PS; Nair MS; Aggarwal BB
Mol Cancer Ther; 2008 Oct; 7(10):3306-17. PubMed ID: 18852134
[TBL] [Abstract][Full Text] [Related]
6. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
Takada Y; Murakami A; Aggarwal BB
Oncogene; 2005 Oct; 24(46):6957-69. PubMed ID: 16007145
[TBL] [Abstract][Full Text] [Related]
7. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway.
Pandey MK; Sung B; Ahn KS; Kunnumakkara AB; Chaturvedi MM; Aggarwal BB
Blood; 2007 Nov; 110(10):3517-25. PubMed ID: 17673602
[TBL] [Abstract][Full Text] [Related]
8. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation.
Sethi G; Ahn KS; Pandey MK; Aggarwal BB
Blood; 2007 Apr; 109(7):2727-35. PubMed ID: 17110449
[TBL] [Abstract][Full Text] [Related]
9. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation.
Takada Y; Gillenwater A; Ichikawa H; Aggarwal BB
J Biol Chem; 2006 Mar; 281(9):5612-22. PubMed ID: 16377638
[TBL] [Abstract][Full Text] [Related]
10. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.
Takada Y; Khuri FR; Aggarwal BB
J Biol Chem; 2004 Jun; 279(25):26287-99. PubMed ID: 15090542
[TBL] [Abstract][Full Text] [Related]
11. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.
Ahn KS; Sethi G; Krishnan K; Aggarwal BB
J Biol Chem; 2007 Jan; 282(1):809-20. PubMed ID: 17114179
[TBL] [Abstract][Full Text] [Related]
12. Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue.
Pandey MK; Sandur SK; Sung B; Sethi G; Kunnumakkara AB; Aggarwal BB
J Biol Chem; 2007 Jun; 282(24):17340-50. PubMed ID: 17439942
[TBL] [Abstract][Full Text] [Related]
13. NF-κB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro.
Li M; Wang X; Liu M; Qi X; Li J
Biomed Pharmacother; 2014 Jun; 68(5):527-35. PubMed ID: 24986326
[TBL] [Abstract][Full Text] [Related]
14. Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis.
Shishodia S; Aggarwal BB
J Biol Chem; 2004 Nov; 279(45):47148-58. PubMed ID: 15322087
[TBL] [Abstract][Full Text] [Related]
15. Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation.
Lee KY; Park JS; Jee YK; Rosen GD
Exp Mol Med; 2002 Dec; 34(6):462-8. PubMed ID: 12526088
[TBL] [Abstract][Full Text] [Related]
16. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.
Sandur SK; Ichikawa H; Sethi G; Ahn KS; Aggarwal BB
J Biol Chem; 2006 Jun; 281(25):17023-17033. PubMed ID: 16624823
[TBL] [Abstract][Full Text] [Related]
17. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
Ichikawa H; Takada Y; Murakami A; Aggarwal BB
J Immunol; 2005 Jun; 174(11):7383-92. PubMed ID: 15905586
[TBL] [Abstract][Full Text] [Related]
18. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
Yadav VR; Prasad S; Gupta SC; Sung B; Phatak SS; Zhang S; Aggarwal BB
J Biol Chem; 2012 Jan; 287(1):245-256. PubMed ID: 22065587
[TBL] [Abstract][Full Text] [Related]
19. Triptolide suppresses growth and hormone secretion in murine pituitary corticotroph tumor cells via NF-kappaB signaling pathway.
Li R; Zhang Z; Wang J; Huang Y; Sun W; Xie R; Hu F; Lei T
Biomed Pharmacother; 2017 Nov; 95():771-779. PubMed ID: 28892788
[TBL] [Abstract][Full Text] [Related]
20. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis.
Sung B; Pandey MK; Ahn KS; Yi T; Chaturvedi MM; Liu M; Aggarwal BB
Blood; 2008 May; 111(10):4880-91. PubMed ID: 18349320
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
