459 related articles for article (PubMed ID: 21821918)
1. Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.
Zode GS; Kuehn MH; Nishimura DY; Searby CC; Mohan K; Grozdanic SD; Bugge K; Anderson MG; Clark AF; Stone EM; Sheffield VC
J Clin Invest; 2011 Sep; 121(9):3542-53. PubMed ID: 21821918
[TBL] [Abstract][Full Text] [Related]
2. Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma.
Zode GS; Bugge KE; Mohan K; Grozdanic SD; Peters JC; Koehn DR; Anderson MG; Kardon RH; Stone EM; Sheffield VC
Invest Ophthalmol Vis Sci; 2012 Mar; 53(3):1557-65. PubMed ID: 22328638
[TBL] [Abstract][Full Text] [Related]
3. Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork.
Kasetti RB; Phan TN; Millar JC; Zode GS
Invest Ophthalmol Vis Sci; 2016 Nov; 57(14):6058-6069. PubMed ID: 27820874
[TBL] [Abstract][Full Text] [Related]
4. Mutated myocilin and heterozygous Sod2 deficiency act synergistically in a mouse model of open-angle glaucoma.
Joe MK; Nakaya N; Abu-Asab M; Tomarev SI
Hum Mol Genet; 2015 Jun; 24(12):3322-34. PubMed ID: 25740847
[TBL] [Abstract][Full Text] [Related]
5. Cross-talk between MYOC p. Y437H mutation and TGF-β2 in the pathology of glaucoma.
Yang Y; Abdulatef ASWA; Zhang L; Jiang H; Zeng Z; Li H; Xia X
Int J Med Sci; 2020; 17(8):1062-1070. PubMed ID: 32410836
[No Abstract] [Full Text] [Related]
6. Accumulation of Asn450Tyr mutant myocilin in ER promotes apoptosis of human trabecular meshwork cells.
Yan X; Wu S; Liu Q; Li Y; Zhu W; Zhang J
Mol Vis; 2020; 26():563-573. PubMed ID: 32818018
[TBL] [Abstract][Full Text] [Related]
7. Intraocular pressure across the lifespan of Tg-MYOC
Zhang X; Xi G; Feng P; Li C; Kuehn MH; Zhu W
Exp Eye Res; 2024 Apr; 241():109855. PubMed ID: 38453040
[TBL] [Abstract][Full Text] [Related]
8. Glaucomatous MYOC mutations activate the IL-1/NF-κB inflammatory stress response and the glaucoma marker SELE in trabecular meshwork cells.
Itakura T; Peters DM; Fini ME
Mol Vis; 2015; 21():1071-84. PubMed ID: 26396484
[TBL] [Abstract][Full Text] [Related]
9. Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye.
van der Heide CJ; Alward WLM; Flamme-Wiese M; Riker M; Syed NA; Anderson MG; Carter K; Kuehn MH; Stone EM; Mullins RF; Fingert JH
Ophthalmol Glaucoma; 2018; 1(2):132-138. PubMed ID: 30906929
[TBL] [Abstract][Full Text] [Related]
10. Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice.
McDowell CM; Luan T; Zhang Z; Putliwala T; Wordinger RJ; Millar JC; John SW; Pang IH; Clark AF
Exp Eye Res; 2012 Jul; 100():65-72. PubMed ID: 22575566
[TBL] [Abstract][Full Text] [Related]
11. Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Patil SV; Kaipa BR; Ranshing S; Sundaresan Y; Millar JC; Nagarajan B; Kiehlbauch C; Zhang Q; Jain A; Searby CC; Scheetz TE; Clark AF; Sheffield VC; Zode GS
Sci Rep; 2024 Mar; 14(1):6958. PubMed ID: 38521856
[TBL] [Abstract][Full Text] [Related]
12. Human Pro370Leu Mutant Myocilin Induces the Phenotype of Open-Angle Glaucoma in Transgenic Mice.
Cheng Y; Wu S; Yan X; Liu Q; Lin D; Zhang J; Wang N
Cell Mol Neurobiol; 2023 Jul; 43(5):2021-2033. PubMed ID: 36069958
[TBL] [Abstract][Full Text] [Related]
13. Tissue plasminogen activator attenuates outflow facility reduction in mouse model of juvenile open angle glaucoma.
Gindina S; Hu Y; Barron AO; Qureshi Z; Danias J
Exp Eye Res; 2020 Oct; 199():108179. PubMed ID: 32739292
[TBL] [Abstract][Full Text] [Related]
14. Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle.
Lynch JM; Dolman AJ; Guo C; Dolan K; Xiang C; Reda S; Li B; Prasanna G
PLoS One; 2018; 13(11):e0206801. PubMed ID: 30395621
[TBL] [Abstract][Full Text] [Related]
15. Myocilin Gene Mutation Induced Autophagy Activation Causes Dysfunction of Trabecular Meshwork Cells.
Yan X; Wu S; Liu Q; Cheng Y; Zhang J; Wang N
Front Cell Dev Biol; 2022; 10():900777. PubMed ID: 35615698
[TBL] [Abstract][Full Text] [Related]
16. Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma.
Liu Y; Allingham RR; Qin X; Layfield D; Dellinger AE; Gibson J; Wheeler J; Ashley-Koch AE; Stamer WD; Hauser MA
Invest Ophthalmol Vis Sci; 2013 Sep; 54(9):6382-9. PubMed ID: 24003086
[TBL] [Abstract][Full Text] [Related]
17. Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma.
Stothert AR; Fontaine SN; Sabbagh JJ; Dickey CA
Exp Eye Res; 2016 Mar; 144():38-45. PubMed ID: 26302411
[TBL] [Abstract][Full Text] [Related]
18. Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells.
Joe MK; Sohn S; Hur W; Moon Y; Choi YR; Kee C
Biochem Biophys Res Commun; 2003 Dec; 312(3):592-600. PubMed ID: 14680806
[TBL] [Abstract][Full Text] [Related]
19. Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma.
Gould DB; Reedy M; Wilson LA; Smith RS; Johnson RL; John SW
Mol Cell Biol; 2006 Nov; 26(22):8427-36. PubMed ID: 16954374
[TBL] [Abstract][Full Text] [Related]
20. Expression of myocilin mutants sensitizes cells to oxidative stress-induced apoptosis: implication for glaucoma pathogenesis.
Joe MK; Tomarev SI
Am J Pathol; 2010 Jun; 176(6):2880-90. PubMed ID: 20382707
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
