BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 21822300)

  • 1. PP2A-B56α controls oncogene-induced senescence in normal and tumor human melanocytic cells.
    Mannava S; Omilian AR; Wawrzyniak JA; Fink EE; Zhuang D; Miecznikowski JC; Marshall JR; Soengas MS; Sears RC; Morrison CD; Nikiforov MA
    Oncogene; 2012 Mar; 31(12):1484-92. PubMed ID: 21822300
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells.
    Zhuang D; Mannava S; Grachtchouk V; Tang WH; Patil S; Wawrzyniak JA; Berman AE; Giordano TJ; Prochownik EV; Soengas MS; Nikiforov MA
    Oncogene; 2008 Nov; 27(52):6623-34. PubMed ID: 18679422
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation.
    Arnold HK; Sears RC
    Mol Cell Biol; 2006 Apr; 26(7):2832-44. PubMed ID: 16537924
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model.
    Janghorban M; Langer EM; Wang X; Zachman D; Daniel CJ; Hooper J; Fleming WH; Agarwal A; Sears RC
    PLoS One; 2017; 12(11):e0188910. PubMed ID: 29190822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.
    Arnold HK; Sears RC
    Cancer Metastasis Rev; 2008 Jun; 27(2):147-58. PubMed ID: 18246411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.
    Vredeveld LC; Possik PA; Smit MA; Meissl K; Michaloglou C; Horlings HM; Ajouaou A; Kortman PC; Dankort D; McMahon M; Mooi WJ; Peeper DS
    Genes Dev; 2012 May; 26(10):1055-69. PubMed ID: 22549727
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression.
    Zhang L; Zhou H; Li X; Vartuli RL; Rowse M; Xing Y; Rudra P; Ghosh D; Zhao R; Ford HL
    Nat Commun; 2018 Mar; 9(1):1047. PubMed ID: 29535359
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protooncogene MYC drives human melanocyte melanogenesis and senescence.
    San Juan L; Cagigal ML; Fernandez-Flores A; Mayorga M; Gandarillas A
    Cancer Gene Ther; 2022 Aug; 29(8-9):1160-1167. PubMed ID: 35022520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function.
    van Tuyn J; Jaber-Hijazi F; MacKenzie D; Cole JJ; Mann E; Pawlikowski JS; Rai TS; Nelson DM; McBryan T; Ivanov A; Blyth K; Wu H; Milling S; Adams PD
    J Invest Dermatol; 2017 Oct; 137(10):2197-2207. PubMed ID: 28647344
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A.
    Pavic K; Gupta N; Omella JD; Derua R; Aakula A; Huhtaniemi R; Määttä JA; Höfflin N; Okkeri J; Wang Z; Kauko O; Varjus R; Honkanen H; Abankwa D; Köhn M; Hytönen VP; Xu W; Nilsson J; Page R; Janssens V; Leitner A; Westermarck J
    Nat Commun; 2023 Feb; 14(1):1143. PubMed ID: 36854761
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma.
    Kaplon J; Hömig-Hölzel C; Gao L; Meissl K; Verdegaal EM; van der Burg SH; van Doorn R; Peeper DS
    Pigment Cell Melanoma Res; 2014 Jul; 27(4):640-52. PubMed ID: 24703243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cells.
    Ruvolo VR; Kurinna SM; Karanjeet KB; Schuster TF; Martelli AM; McCubrey JA; Ruvolo PP
    J Biol Chem; 2008 Dec; 283(51):35474-85. PubMed ID: 18957415
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of cellular protooncogene activation and transformation-related activity of human melanocytes and metastatic melanoma.
    Husain Z; FitzGerald GB; Wick MM
    J Invest Dermatol; 1990 Nov; 95(5):571-5. PubMed ID: 2121834
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear export and centrosome targeting of the protein phosphatase 2A subunit B56alpha: role of B56alpha in nuclear export of the catalytic subunit.
    Flegg CP; Sharma M; Medina-Palazon C; Jamieson C; Galea M; Brocardo MG; Mills K; Henderson BR
    J Biol Chem; 2010 Jun; 285(24):18144-54. PubMed ID: 20378546
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart.
    Little SC; Curran J; Makara MA; Kline CF; Ho HT; Xu Z; Wu X; Polina I; Musa H; Meadows AM; Carnes CA; Biesiadecki BJ; Davis JP; Weisleder N; Györke S; Wehrens XH; Hund TJ; Mohler PJ
    Sci Signal; 2015 Jul; 8(386):ra72. PubMed ID: 26198358
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence.
    Kluge V; Kappelmann-Fenzl M; Fischer S; Zimmermann T; Pommer M; Kuphal S; Bosserhoff AK
    Cell Death Dis; 2024 Feb; 15(2):166. PubMed ID: 38388496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. B56α subunit of protein phosphatase 2A mediates retinoic acid-induced decreases in phosphorylation of endothelial nitric oxide synthase at serine 1179 and nitric oxide production in bovine aortic endothelial cells.
    Park JH; Sung HY; Lee JY; Kim HJ; Ahn JH; Jo I
    Biochem Biophys Res Commun; 2013 Jan; 430(2):476-81. PubMed ID: 23237802
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes.
    Yu H; McDaid R; Lee J; Possik P; Li L; Kumar SM; Elder DE; Van Belle P; Gimotty P; Guerra M; Hammond R; Nathanson KL; Dalla Palma M; Herlyn M; Xu X
    Am J Pathol; 2009 Jun; 174(6):2367-77. PubMed ID: 19389934
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of PP2A complexes and pathways involved in cell transformation.
    Sablina AA; Hector M; Colpaert N; Hahn WC
    Cancer Res; 2010 Dec; 70(24):10474-84. PubMed ID: 21159657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amphiregulin Regulates Melanocytic Senescence.
    Pommer M; Kuphal S; Bosserhoff AK
    Cells; 2021 Feb; 10(2):. PubMed ID: 33562468
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.