BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 21822681)

  • 1. Effects of clonal variation on growth, metabolism, and productivity in response to trophic factor stimulation: a study of Chinese hamster ovary cells producing a recombinant monoclonal antibody.
    Dahodwala H; Nowey M; Mitina T; Sharfstein ST
    Cytotechnology; 2012 Jan; 64(1):27-41. PubMed ID: 21822681
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1.
    Matsuyama R; Yamano N; Kawamura N; Omasa T
    J Biosci Bioeng; 2017 Mar; 123(3):382-389. PubMed ID: 27742176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differences in optimal pH and temperature for cell growth and antibody production between two Chinese hamster ovary clones derived from the same parental clone.
    Kim HS; Lee GM
    J Microbiol Biotechnol; 2007 May; 17(5):712-20. PubMed ID: 18051290
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhancing effect of low culture temperature on specific antibody productivity of recombinant Chinese hamster ovary cells: clonal variation.
    Yoon SK; Hwang SO; Lee GM
    Biotechnol Prog; 2004; 20(6):1683-8. PubMed ID: 15575699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Metabolomics Approach to Increasing Chinese Hamster Ovary (CHO) Cell Productivity.
    Yao G; Aron K; Borys M; Li Z; Pendse G; Lee K
    Metabolites; 2021 Nov; 11(12):. PubMed ID: 34940581
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analyzing clonal variation of monoclonal antibody-producing CHO cell lines using an in silico metabolomic platform.
    Ghorbaniaghdam A; Chen J; Henry O; Jolicoeur M
    PLoS One; 2014; 9(3):e90832. PubMed ID: 24632968
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Short-hairpin-RNA-mediated silencing of fucosyltransferase 8 in Chinese-hamster ovary cells for the production of antibodies with enhanced antibody immune effector function.
    Beuger V; Künkele KP; Koll H; Gärtner A; Bähner M; Burtscher H; Klein C
    Biotechnol Appl Biochem; 2009 May; 53(Pt 1):31-7. PubMed ID: 19032154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
    Figueroa B; Ailor E; Osborne D; Hardwick JM; Reff M; Betenbaugh MJ
    Biotechnol Bioeng; 2007 Jul; 97(4):877-92. PubMed ID: 17099908
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clonal variations in CHO IGF signaling investigated by SILAC-based phosphoproteomics and LFQ-MS.
    Schelletter L; Albaum S; Walter S; Noll T; Hoffrogge R
    Appl Microbiol Biotechnol; 2019 Oct; 103(19):8127-8143. PubMed ID: 31420692
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapid establishment of CHO cell lines producing the anti-hepatocyte growth factor antibody SFN68.
    Song SW; Lee SJ; Kim CY; Han B; Oh JW
    J Microbiol Biotechnol; 2013 Aug; 23(8):1176-84. PubMed ID: 23727793
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
    Fan L; Kadura I; Krebs LE; Hatfield CC; Shaw MM; Frye CC
    Biotechnol Bioeng; 2012 Apr; 109(4):1007-15. PubMed ID: 22068567
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells.
    Loh WP; Loo B; Zhou L; Zhang P; Lee DY; Yang Y; Lam KP
    Biotechnol J; 2014 Sep; 9(9):1140-51. PubMed ID: 24819042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A quantitative proteomic analysis of cellular responses to high glucose media in Chinese hamster ovary cells.
    Liu Z; Dai S; Bones J; Ray S; Cha S; Karger BL; Li JJ; Wilson L; Hinckle G; Rossomando A
    Biotechnol Prog; 2015; 31(4):1026-38. PubMed ID: 25857574
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combined gene and environmental engineering offers a synergetic strategy to enhance r-protein production in Chinese hamster ovary cells.
    Torres M; Dickson AJ
    Biotechnol Bioeng; 2022 Feb; 119(2):550-565. PubMed ID: 34821376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Correlation between enhancing effect of sodium butyrate on specific productivity and mRNA transcription level in recombinant Chinese hamster ovary cells producing antibody.
    Jeon MK; Lee GM
    J Microbiol Biotechnol; 2007 Jun; 17(6):1036-40. PubMed ID: 18050924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Using Titer and Titer Normalized to Confluence Are Complementary Strategies for Obtaining Chinese Hamster Ovary Cell Lines with High Volumetric Productivity of Etanercept.
    Pristovšek N; Hansen HG; Sergeeva D; Borth N; Lee GM; Andersen MR; Kildegaard HF
    Biotechnol J; 2018 Mar; 13(3):e1700216. PubMed ID: 29359860
    [