BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 21824286)

  • 1. Mutant telomerase RNAs induce DNA damage and apoptosis via the TRF2-ATM pathway in telomerase-overexpressing primary fibroblasts.
    Mahalingam D; Tay LL; Tan WH; Chai JH; Wang X
    FEBS J; 2011 Oct; 278(19):3724-38. PubMed ID: 21824286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.
    Goldkorn A; Blackburn EH
    Cancer Res; 2006 Jun; 66(11):5763-71. PubMed ID: 16740715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells.
    Stohr BA; Blackburn EH
    Cancer Res; 2008 Jul; 68(13):5309-17. PubMed ID: 18593932
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
    Denchi EL; de Lange T
    Nature; 2007 Aug; 448(7157):1068-71. PubMed ID: 17687332
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
    Powers JT; Hong S; Mayhew CN; Rogers PM; Knudsen ES; Johnson DG
    Mol Cancer Res; 2004 Apr; 2(4):203-14. PubMed ID: 15140942
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
    Celli GB; de Lange T
    Nat Cell Biol; 2005 Jul; 7(7):712-8. PubMed ID: 15968270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA.
    Li S; Rosenberg JE; Donjacour AA; Botchkina IL; Hom YK; Cunha GR; Blackburn EH
    Cancer Res; 2004 Jul; 64(14):4833-40. PubMed ID: 15256453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gallic acid induces apoptosis of lung fibroblasts via a reactive oxygen species-dependent ataxia telangiectasia mutated-p53 activation pathway.
    Chuang CY; Liu HC; Wu LC; Chen CY; Chang JT; Hsu SL
    J Agric Food Chem; 2010 Mar; 58(5):2943-51. PubMed ID: 20151649
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine.
    Zhang YW; Zhang ZX; Miao ZH; Ding J
    Mol Pharmacol; 2008 Mar; 73(3):824-32. PubMed ID: 18025071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity.
    Hou YY; Toh MT; Wang X
    Cell Biochem Funct; 2012 Apr; 30(3):233-42. PubMed ID: 22161642
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells.
    Yim H; Hwang IS; Choi JS; Chun KH; Jin YH; Ham YM; Lee KY; Lee SK
    J Cell Biol; 2006 Jul; 174(1):77-88. PubMed ID: 16801388
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Telomeric plasmid induces human cancer cell dysfunction depending on ATM activity.
    Guo XF; Cao EH
    Cell Biochem Funct; 2010 Jul; 28(5):381-6. PubMed ID: 20535839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p53 governs telomere regulation feedback too, via TRF2.
    Horikawa I; Fujita K; Harris CC
    Aging (Albany NY); 2011 Jan; 3(1):26-32. PubMed ID: 21266744
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ataxia-telangiectasia mutated is not required for p53 induction and apoptosis in irradiated epithelial tissues.
    Gurley KE; Kemp CJ
    Mol Cancer Res; 2007 Dec; 5(12):1312-8. PubMed ID: 18171989
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53.
    Wang J; Pabla N; Wang CY; Wang W; Schoenlein PV; Dong Z
    Am J Physiol Renal Physiol; 2006 Dec; 291(6):F1300-7. PubMed ID: 16849690
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of interferon-stimulated genes by gamma-ray irradiation independently of the ataxia telangiectasia mutated-p53 pathway.
    Sugihara T; Murano H; Nakamura M; Ichinohe K; Tanaka K
    Mol Cancer Res; 2011 Apr; 9(4):476-84. PubMed ID: 21357441
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of beta-carotene-induced apoptosis of gastric cancer cells: involvement of ataxia-telangiectasia-mutated.
    Jang SH; Lim JW; Kim H
    Ann N Y Acad Sci; 2009 Aug; 1171():156-62. PubMed ID: 19723050
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA-dependent protein kinase enhances DNA damage-induced apoptosis in association with Friend gp70.
    Yamaguchi S; Hasegawa M; Aizawa S; Tanaka K; Yoshida K; Noda Y; Tatsumi K; Hirokawa K; Kitagawa M
    Leuk Res; 2005 Mar; 29(3):307-16. PubMed ID: 15661267
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity.
    Yoshida M; Shiojima I; Ikeda H; Komuro I
    J Mol Cell Cardiol; 2009 Nov; 47(5):698-705. PubMed ID: 19660469
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Telomerase inhibition induces acute ATM-dependent growth arrest in human astrocytomas.
    Wong VC; Ma J; Hawkins CE
    Cancer Lett; 2009 Feb; 274(1):151-9. PubMed ID: 18945545
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.