BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

450 related articles for article (PubMed ID: 21825135)

  • 1. ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1.
    Sannerud R; Declerck I; Peric A; Raemaekers T; Menendez G; Zhou L; Veerle B; Coen K; Munck S; De Strooper B; Schiavo G; Annaert W
    Proc Natl Acad Sci U S A; 2011 Aug; 108(34):E559-68. PubMed ID: 21825135
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting.
    John BA; Meister M; Banning A; Tikkanen R
    FEBS J; 2014 Apr; 281(8):2074-87. PubMed ID: 24612608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway.
    Toh WH; Tan JZ; Zulkefli KL; Houghton FJ; Gleeson PA
    Traffic; 2017 Mar; 18(3):159-175. PubMed ID: 28000370
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BACE1 protein endocytosis and trafficking are differentially regulated by ubiquitination at lysine 501 and the Di-leucine motif in the carboxyl terminus.
    Kang EL; Biscaro B; Piazza F; Tesco G
    J Biol Chem; 2012 Dec; 287(51):42867-80. PubMed ID: 23109336
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.
    Toh WH; Chia PZC; Hossain MI; Gleeson PA
    Mol Biol Cell; 2018 Jan; 29(2):191-208. PubMed ID: 29142073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.
    Bhattacharyya R; Teves CAF; Long A; Hofert M; Tanzi RE
    Sci Rep; 2022 Mar; 12(1):3486. PubMed ID: 35241726
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced cleavage of APP by co-expressed Bace1 alters the distribution of APP and its fragments in neuronal and non-neuronal cells.
    Aow J; Huang TR; Thinakaran G; Koo EH
    Mol Neurobiol; 2022 May; 59(5):3073-3090. PubMed ID: 35266114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.
    Prabhu Y; Burgos PV; Schindler C; Farías GG; Magadán JG; Bonifacino JS
    Mol Biol Cell; 2012 Jun; 23(12):2339-51. PubMed ID: 22553349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
    Wang M; Jing T; Wang X; Yao D
    Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.
    Zhao Y; Wang Y; Yang J; Wang X; Zhao Y; Zhang X; Zhang YW
    Mol Neurodegener; 2012 Jun; 7():30. PubMed ID: 22709416
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.
    Herskowitz JH; Offe K; Deshpande A; Kahn RA; Levey AI; Lah JJ
    Mol Biol Cell; 2012 Jul; 23(14):2645-57. PubMed ID: 22621900
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The
    Tan JZA; Gleeson PA
    J Biol Chem; 2019 Feb; 294(5):1618-1631. PubMed ID: 30545942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intracellular itinerary of internalised β-secretase, BACE1, and its potential impact on β-amyloid peptide biogenesis.
    Chia PZ; Toh WH; Sharples R; Gasnereau I; Hill AF; Gleeson PA
    Traffic; 2013 Sep; 14(9):997-1013. PubMed ID: 23773724
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
    von Einem B; Wahler A; Schips T; Serrano-Pozo A; Proepper C; Boeckers TM; Rueck A; Wirth T; Hyman BT; Danzer KM; Thal DR; von Arnim CA
    PLoS One; 2015; 10(6):e0129047. PubMed ID: 26053850
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production.
    Tan JZA; Fourriere L; Wang J; Perez F; Boncompain G; Gleeson PA
    Mol Biol Cell; 2020 Jan; 31(1):27-44. PubMed ID: 31746668
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes.
    Tang W; Tam JH; Seah C; Chiu J; Tyrer A; Cregan SP; Meakin SO; Pasternak SH
    Mol Brain; 2015 Jul; 8():41. PubMed ID: 26170135
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
    Kurkinen KM; Marttinen M; Turner L; Natunen T; Mäkinen P; Haapalinna F; Sarajärvi T; Gabbouj S; Kurki M; Paananen J; Koivisto AM; Rauramaa T; Leinonen V; Tanila H; Soininen H; Lucas FR; Haapasalo A; Hiltunen M
    J Cell Sci; 2016 Jun; 129(11):2224-38. PubMed ID: 27084579
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP cleaving protein 1 (BACE1).
    Zhao Y; Wang Y; Hu J; Zhang X; Zhang YW
    J Biol Chem; 2012 Mar; 287(14):11141-50. PubMed ID: 22351782
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.