BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 21829496)

  • 1. LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines.
    Walker F; Zhang HH; Odorizzi A; Burgess AW
    PLoS One; 2011; 6(7):e22733. PubMed ID: 21829496
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prognostic significance of leucine-rich-repeat-containing G-protein-coupled receptor 5, an intestinal stem cell marker, in gastric carcinomas.
    Jang BG; Lee BL; Kim WH
    Gastric Cancer; 2016 Jul; 19(3):767-77. PubMed ID: 26386561
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.
    Hsu HC; Liu YS; Tseng KC; Yang TS; Yeh CY; You JF; Hung HY; Chen SJ; Chen HC
    J Cancer Res Clin Oncol; 2015 Jan; 141(1):11-21. PubMed ID: 25060070
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
    Hua F; Shang S; Yang YW; Zhang HZ; Xu TL; Yu JJ; Zhou DD; Cui B; Li K; Lv XX; Zhang XW; Liu SS; Yu JM; Wang F; Zhang C; Huang B; Hu ZW
    Gastroenterology; 2019 Feb; 156(3):708-721.e15. PubMed ID: 30365932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.
    Fafilek B; Krausova M; Vojtechova M; Pospichalova V; Tumova L; Sloncova E; Huranova M; Stancikova J; Hlavata A; Svec J; Sedlacek R; Luksan O; Oliverius M; Voska L; Jirsa M; Paces J; Kolar M; Krivjanska M; Klimesova K; Tlaskalova-Hogenova H; Korinek V
    Gastroenterology; 2013 Feb; 144(2):381-391. PubMed ID: 23142137
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LGR5 promotes cancer stem cell traits and chemoresistance in cervical cancer.
    Cao HZ; Liu XF; Yang WT; Chen Q; Zheng PS
    Cell Death Dis; 2017 Sep; 8(9):e3039. PubMed ID: 28880275
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs.
    Al-Kharusi MR; Smartt HJ; Greenhough A; Collard TJ; Emery ED; Williams AC; Paraskeva C
    Carcinogenesis; 2013 May; 34(5):1150-7. PubMed ID: 23349017
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dietary energy balance modulates epithelial-to-mesenchymal transition and tumor progression in murine claudin-low and basal-like mammary tumor models.
    Dunlap SM; Chiao LJ; Nogueira L; Usary J; Perou CM; Varticovski L; Hursting SD
    Cancer Prev Res (Phila); 2012 Jul; 5(7):930-42. PubMed ID: 22588949
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer.
    Leng Z; Xia Q; Chen J; Li Y; Xu J; Zhao E; Zheng H; Ai W; Dong J
    Cell Physiol Biochem; 2018; 46(2):860-872. PubMed ID: 29627827
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Significance of Lgr5(+ve) cancer stem cells in the colon and rectum.
    Takahashi H; Ishii H; Nishida N; Takemasa I; Mizushima T; Ikeda M; Yokobori T; Mimori K; Yamamoto H; Sekimoto M; Doki Y; Mori M
    Ann Surg Oncol; 2011 Apr; 18(4):1166-74. PubMed ID: 21125339
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/β-catenin signaling pathway in colorectal cancer cells.
    Hsu HC; Liu YS; Tseng KC; Tan BC; Chen SJ; Chen HC
    Cell Signal; 2014 Nov; 26(11):2333-42. PubMed ID: 25025569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/β-catenin pathway and predicts poor survival of glioma patients.
    Zhang J; Cai H; Sun L; Zhan P; Chen M; Zhang F; Ran Y; Wan J
    J Exp Clin Cancer Res; 2018 Sep; 37(1):225. PubMed ID: 30208924
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1.
    Wang B; Chen Q; Cao Y; Ma X; Yin C; Jia Y; Zang A; Fan W
    PLoS One; 2016; 11(12):e0168904. PubMed ID: 28033430
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Study on the Mechanism of Low-Expressed Cancer Stem Cell Marker Lgr5 in Inhibition of the Proliferation and Invasion of Colorectal Carcinoma.
    Jia H; Xiang L; Wang Z; Zhou Q
    Cell Biochem Biophys; 2015 Nov; 73(2):393-397. PubMed ID: 27352328
    [TBL] [Abstract][Full Text] [Related]  

  • 15. OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion.
    Dai X; Ge J; Wang X; Qian X; Zhang C; Li X
    Oncol Rep; 2013 Jan; 29(1):155-60. PubMed ID: 23076549
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells.
    Kemper K; Prasetyanti PR; De Lau W; Rodermond H; Clevers H; Medema JP
    Stem Cells; 2012 Nov; 30(11):2378-86. PubMed ID: 22969042
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lgr4 promotes glioma cell proliferation through activation of Wnt signaling.
    Yu CY; Liang GB; Du P; Liu YH
    Asian Pac J Cancer Prev; 2013; 14(8):4907-11. PubMed ID: 24083766
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression Profile of LGR5 and Its Prognostic Significance in Colorectal Cancer Progression.
    Jang BG; Kim HS; Chang WY; Bae JM; Kim WH; Kang GH
    Am J Pathol; 2018 Oct; 188(10):2236-2250. PubMed ID: 30036518
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.
    Garcia MI; Ghiani M; Lefort A; Libert F; Strollo S; Vassart G
    Dev Biol; 2009 Jul; 331(1):58-67. PubMed ID: 19394326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NHE8 Deficiency Promotes Colitis-Associated Cancer in Mice via Expansion of Lgr5-Expressing Cells.
    Xu H; Li J; Chen H; Ghishan FK
    Cell Mol Gastroenterol Hepatol; 2019; 7(1):19-31. PubMed ID: 30465020
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.