89 related articles for article (PubMed ID: 21838706)
1. Insight into the molecular basis for the kinetic differences between the two insulin receptor isoforms.
Knudsen L; De Meyts P; Kiselyov VV
Biochem J; 2011 Dec; 440(3):397-403. PubMed ID: 21838706
[TBL] [Abstract][Full Text] [Related]
2. Kinetic evidence for the sequential association of insulin binding sites 1 and 2 to the insulin receptor and the influence of receptor isoform.
Thorsøe KS; Schlein M; Steensgaard DB; Brandt J; Schluckebier G; Naver H
Biochemistry; 2010 Jul; 49(29):6234-46. PubMed ID: 20568733
[TBL] [Abstract][Full Text] [Related]
3. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
Menting JG; Ward CW; Margetts MB; Lawrence MC
Biochemistry; 2009 Jun; 48(23):5492-500. PubMed ID: 19459609
[TBL] [Abstract][Full Text] [Related]
4. Ligand-binding properties of the two isoforms of the human insulin receptor.
Yamaguchi Y; Flier JS; Benecke H; Ransil BJ; Moller DE
Endocrinology; 1993 Mar; 132(3):1132-8. PubMed ID: 8440175
[TBL] [Abstract][Full Text] [Related]
5. Structural insights into ligand-induced activation of the insulin receptor.
Ward C; Lawrence M; Streltsov V; Garrett T; McKern N; Lou MZ; Lovrecz G; Adams T
Acta Physiol (Oxf); 2008 Jan; 192(1):3-9. PubMed ID: 18171424
[TBL] [Abstract][Full Text] [Related]
6. Receptor-isoform-selective insulin analogues give tissue-preferential effects.
Vienberg SG; Bouman SD; Sørensen H; Stidsen CE; Kjeldsen T; Glendorf T; Sørensen AR; Olsen GS; Andersen B; Nishimura E
Biochem J; 2011 Dec; 440(3):301-8. PubMed ID: 21851336
[TBL] [Abstract][Full Text] [Related]
7. Insulin receptor structure and its implications for the IGF-1 receptor.
Lawrence MC; McKern NM; Ward CW
Curr Opin Struct Biol; 2007 Dec; 17(6):699-705. PubMed ID: 17851071
[TBL] [Abstract][Full Text] [Related]
8. Increased levels of insulin and insulin-like growth factor-1 hybrid receptors and decreased glycosylation of the insulin receptor alpha- and beta-subunits in scrapie-infected neuroblastoma N2a cells.
Nielsen D; Gyllberg H; Ostlund P; Bergman T; Bedecs K
Biochem J; 2004 Jun; 380(Pt 2):571-9. PubMed ID: 15025560
[TBL] [Abstract][Full Text] [Related]
9. Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site.
van der Geer P; Wiley S; Pawson T
Oncogene; 1999 May; 18(20):3071-5. PubMed ID: 10340378
[TBL] [Abstract][Full Text] [Related]
10. Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments.
Nakamura T; Takahashi H; Takahashi M; Shimba N; Suzuki E; Shimada I
J Med Chem; 2010 Mar; 53(5):1917-22. PubMed ID: 20158183
[TBL] [Abstract][Full Text] [Related]
11. Purification and properties of insulin receptor ectodomain from large-scale mammalian cell culture.
Cosgrove L; Lovrecz GO; Verkuylen A; Cavaleri L; Black LA; Bentley JD; Howlett GJ; Gray PP; Ward CW; McKern NM
Protein Expr Purif; 1995 Dec; 6(6):789-98. PubMed ID: 8746631
[TBL] [Abstract][Full Text] [Related]
12. Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
Whitten AE; Smith BJ; Menting JG; Margetts MB; McKern NM; Lovrecz GO; Adams TE; Richards K; Bentley JD; Trewhella J; Ward CW; Lawrence MC
J Mol Biol; 2009 Dec; 394(5):878-92. PubMed ID: 19835884
[TBL] [Abstract][Full Text] [Related]
13. Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.
Ahmed Z; Pillay TS
Biochem J; 2003 Apr; 371(Pt 2):405-12. PubMed ID: 12521378
[TBL] [Abstract][Full Text] [Related]
14. The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
Denley A; Wallace JC; Cosgrove LJ; Forbes BE
Horm Metab Res; 2003; 35(11-12):778-85. PubMed ID: 14710358
[TBL] [Abstract][Full Text] [Related]
15. Identification of Ser(1275) and Ser(1309) as autophosphorylation sites of the human insulin receptor in intact cells.
Tennagels N; Telting D; Parvaresch S; Maassen JA; Klein HW
Biochem Biophys Res Commun; 2001 Mar; 282(2):387-93. PubMed ID: 11401470
[TBL] [Abstract][Full Text] [Related]
16. Structure of the insulin receptor ectodomain reveals a folded-over conformation.
McKern NM; Lawrence MC; Streltsov VA; Lou MZ; Adams TE; Lovrecz GO; Elleman TC; Richards KM; Bentley JD; Pilling PA; Hoyne PA; Cartledge KA; Pham TM; Lewis JL; Sankovich SE; Stoichevska V; Da Silva E; Robinson CP; Frenkel MJ; Sparrow LG; Fernley RT; Epa VC; Ward CW
Nature; 2006 Sep; 443(7108):218-21. PubMed ID: 16957736
[TBL] [Abstract][Full Text] [Related]
17. Insulin and its analogs: actions via insulin and IGF receptors.
Vigneri R; Squatrito S; Sciacca L
Acta Diabetol; 2010 Dec; 47(4):271-8. PubMed ID: 20730455
[TBL] [Abstract][Full Text] [Related]
18. Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
Ward CW; Lawrence MC
Bioessays; 2009 Apr; 31(4):422-34. PubMed ID: 19274663
[TBL] [Abstract][Full Text] [Related]
19. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
Farris W; Leissring MA; Hemming ML; Chang AY; Selkoe DJ
Biochemistry; 2005 May; 44(17):6513-25. PubMed ID: 15850385
[TBL] [Abstract][Full Text] [Related]
20. An arginine to cysteine(252) mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves signalling events.
Hamer I; Foti M; Emkey R; Cordier-Bussat M; Philippe J; De Meyts P; Maeder C; Kahn CR; Carpentier JL
Diabetologia; 2002 May; 45(5):657-67. PubMed ID: 12107746
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
