These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 21840216)

  • 21. In vitro and in vivo anti-Trypanosoma brucei activities of phenazinomycin and related compounds.
    Otoguro K; Ishiyama A; Iwatsuki M; Namatame M; Nishihara-Tukashima A; Nakashima T; Shibahara S; Kondo S; Yamada H; Omura S
    J Antibiot (Tokyo); 2010 Sep; 63(9):579-81. PubMed ID: 20588299
    [No Abstract]   [Full Text] [Related]  

  • 22. Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models.
    Mallari JP; Zhu F; Lemoff A; Kaiser M; Lu M; Brun R; Guy RK
    Bioorg Med Chem; 2010 Dec; 18(23):8302-9. PubMed ID: 21051236
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of Ser424 as the protein kinase A phosphorylation site in CTP synthetase from Saccharomyces cerevisiae.
    Park TS; Ostrander DB; Pappas A; Carman GM
    Biochemistry; 1999 Jul; 38(27):8839-48. PubMed ID: 10393561
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis.
    Bearne SL; Hekmat O; Macdonnell JE
    Biochem J; 2001 May; 356(Pt 1):223-32. PubMed ID: 11336655
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5'-Triphosphate.
    McCluskey GD; Mohamady S; Taylor SD; Bearne SL
    Chembiochem; 2016 Dec; 17(23):2240-2249. PubMed ID: 27643605
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents.
    Vicik R; Hoerr V; Glaser M; Schultheis M; Hansell E; McKerrow JH; Holzgrabe U; Caffrey CR; Ponte-Sucre A; Moll H; Stich A; Schirmeister T
    Bioorg Med Chem Lett; 2006 May; 16(10):2753-7. PubMed ID: 16516467
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pharmacophore identification of ascofuranone, potent inhibitor of cyanide-insensitive alternative oxidase of Trypanosoma brucei.
    Saimoto H; Kido Y; Haga Y; Sakamoto K; Kita K
    J Biochem; 2013 Mar; 153(3):267-73. PubMed ID: 23180806
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents.
    Ohkanda J; Buckner FS; Lockman JW; Yokoyama K; Carrico D; Eastman R; de Luca-Fradley K; Davies W; Croft SL; Van Voorhis WC; Gelb MH; Sebti SM; Hamilton AD
    J Med Chem; 2004 Jan; 47(2):432-45. PubMed ID: 14711313
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Targeting the nucleotide metabolism of Trypanosoma brucei and other trypanosomatids.
    Hofer A
    FEMS Microbiol Rev; 2023 May; 47(3):. PubMed ID: 37156497
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Adenosine kinase mediates high affinity adenosine salvage in Trypanosoma brucei.
    Vodnala M; Fijolek A; Rofougaran R; Mosimann M; Mäser P; Hofer A
    J Biol Chem; 2008 Feb; 283(9):5380-8. PubMed ID: 18167353
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Trypanosoma brucei: effects of methoprene and other isoprenoid compounds on procyclic and bloodstream forms in vitro and in mice.
    Harmon MA; Scott TC; Li Y; Boehm MF; Phillips MA; Mangelsdorf DJ
    Exp Parasitol; 1997 Nov; 87(3):229-36. PubMed ID: 9371088
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis.
    Berg M; Kohl L; Van der Veken P; Joossens J; Al-Salabi MI; Castagna V; Giannese F; Cos P; Versées W; Steyaert J; Grellier P; Haemers A; Degano M; Maes L; de Koning HP; Augustyns K
    Antimicrob Agents Chemother; 2010 May; 54(5):1900-8. PubMed ID: 20194690
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP incoupling between glutamine hydrolysis and CTP synthesis.
    Willemoës M; Sigurskjold BW
    Eur J Biochem; 2002 Oct; 269(19):4772-9. PubMed ID: 12354108
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In silico drug re-purposing against African sleeping sickness using GlcNAc-PI de-N-acetylase as an experimental target.
    Rashmi M; Swati D
    Comput Biol Chem; 2015 Dec; 59 Pt A():87-94. PubMed ID: 26476127
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.
    Urbaniak MD; Tabudravu JN; Msaki A; Matera KM; Brenk R; Jaspars M; Ferguson MA
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5744-7. PubMed ID: 16962325
    [TBL] [Abstract][Full Text] [Related]  

  • 36. In vitro trypanocidal activity of the anti-helminthic drug niclosamide.
    Merschjohann K; Steverding D
    Exp Parasitol; 2008 Apr; 118(4):637-40. PubMed ID: 18226810
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1.
    Chambers JW; Fowler ML; Morris MT; Morris JC
    Mol Biochem Parasitol; 2008 Apr; 158(2):202-7. PubMed ID: 18262292
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei.
    Alloatti A; Gupta S; Gualdrón-López M; Nguewa PA; Altabe SG; Deumer G; Wallemacq P; Michels PA; Uttaro AD
    Biochem Biophys Res Commun; 2011 Aug; 412(2):286-90. PubMed ID: 21820408
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.
    Jacobs RT; Plattner JJ; Nare B; Wring SA; Chen D; Freund Y; Gaukel EG; Orr MD; Perales JB; Jenks M; Noe RA; Sligar JM; Zhang YK; Bacchi CJ; Yarlett N; Don R
    Future Med Chem; 2011 Aug; 3(10):1259-78. PubMed ID: 21859301
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble vacuolar pyrophosphatase.
    Kotsikorou E; Song Y; Chan JM; Faelens S; Tovian Z; Broderick E; Bakalara N; Docampo R; Oldfield E
    J Med Chem; 2005 Sep; 48(19):6128-39. PubMed ID: 16162013
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.