194 related articles for article (PubMed ID: 21840485)
21. Primary constitutional MLH1 epimutations: a focal epigenetic event.
Dámaso E; Castillejo A; Arias MDM; Canet-Hermida J; Navarro M; Del Valle J; Campos O; Fernández A; Marín F; Turchetti D; García-Díaz JD; Lázaro C; Genuardi M; Rueda D; Alonso Á; Soto JL; Hitchins M; Pineda M; Capellá G
Br J Cancer; 2018 Oct; 119(8):978-987. PubMed ID: 30283143
[TBL] [Abstract][Full Text] [Related]
22. Highly sensitive MLH1 methylation analysis in blood identifies a cancer patient with low-level mosaic MLH1 epimutation.
Dámaso E; Canet-Hermida J; Vargas-Parra G; Velasco À; Marín F; Darder E; Del Valle J; Fernández A; Izquierdo À; Mateu G; Oliveras G; Escribano C; Piñol V; Uchima HI; Soto JL; Hitchins M; Farrés R; Lázaro C; Queralt B; Brunet J; Capellá G; Pineda M
Clin Epigenetics; 2019 Nov; 11(1):171. PubMed ID: 31779681
[TBL] [Abstract][Full Text] [Related]
23. Germline epimutation of MLH1 in individuals with multiple cancers.
Suter CM; Martin DI; Ward RL
Nat Genet; 2004 May; 36(5):497-501. PubMed ID: 15064764
[TBL] [Abstract][Full Text] [Related]
24. Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer.
Hitchins MP; Lin VA; Buckle A; Cheong K; Halani N; Ku S; Kwok CT; Packham D; Suter CM; Meagher A; Stirzaker C; Clark S; Hawkins NJ; Ward RL
Cancer Res; 2007 Oct; 67(19):9107-16. PubMed ID: 17909015
[TBL] [Abstract][Full Text] [Related]
25. Biallelic MLH1 SNP cDNA expression or constitutional promoter methylation can hide genomic rearrangements causing Lynch syndrome.
Morak M; Koehler U; Schackert HK; Steinke V; Royer-Pokora B; Schulmann K; Kloor M; Höchter W; Weingart J; Keiling C; Massdorf T; Holinski-Feder E;
J Med Genet; 2011 Aug; 48(8):513-9. PubMed ID: 21712435
[TBL] [Abstract][Full Text] [Related]
26. Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles.
Auclair J; Vaissière T; Desseigne F; Lasset C; Bonadona V; Giraud S; Saurin JC; Joly MO; Leroux D; Faivre L; Audoynaud C; Montmain G; Ruano E; Herceg Z; Puisieux A; Wang Q
Genes Chromosomes Cancer; 2011 Mar; 50(3):178-85. PubMed ID: 21213371
[TBL] [Abstract][Full Text] [Related]
27. Inherited epimutation or a haplotypic basis for the propensity to silence?
Suter CM; Martin DI
Nat Genet; 2007 May; 39(5):573; author reply 576. PubMed ID: 17460681
[No Abstract] [Full Text] [Related]
28. The importance of proper bioinformatics analysis and clinical interpretation of tumor genomic profiling: a case study of undifferentiated sarcoma and a constitutional pathogenic BRCA2 mutation and an MLH1 variant of uncertain significance.
Varga E; Chao EC; Yeager ND
Fam Cancer; 2015 Sep; 14(3):481-5. PubMed ID: 25712765
[TBL] [Abstract][Full Text] [Related]
29. Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.
Lin JC; Jeong S; Liang G; Takai D; Fatemi M; Tsai YC; Egger G; Gal-Yam EN; Jones PA
Cancer Cell; 2007 Nov; 12(5):432-44. PubMed ID: 17996647
[TBL] [Abstract][Full Text] [Related]
30. Redundant DNA methylation in colorectal cancers of Lynch-syndrome patients.
Alemayehu A; Sebova K; Fridrichova I
Genes Chromosomes Cancer; 2008 Oct; 47(10):906-14. PubMed ID: 18618713
[TBL] [Abstract][Full Text] [Related]
31. Epigenetic mechanisms in the pathogenesis of Lynch syndrome.
Peltomäki P
Clin Genet; 2014 May; 85(5):403-12. PubMed ID: 24443998
[TBL] [Abstract][Full Text] [Related]
32. Haplotype defined by the MLH1-93G/A polymorphism is associated with MLH1 promoter hypermethylation in sporadic colorectal cancers.
Miyakura Y; Tahara M; Lefor AT; Yasuda Y; Sugano K
BMC Res Notes; 2014 Nov; 7():835. PubMed ID: 25421847
[TBL] [Abstract][Full Text] [Related]
33. Epigenetic signatures of familial cancer are characteristic of tumor type and family category.
Joensuu EI; Abdel-Rahman WM; Ollikainen M; Ruosaari S; Knuutila S; Peltomäki P
Cancer Res; 2008 Jun; 68(12):4597-605. PubMed ID: 18559504
[TBL] [Abstract][Full Text] [Related]
34. Coexisting somatic promoter hypermethylation and pathogenic MLH1 germline mutation in Lynch syndrome.
Rahner N; Friedrichs N; Steinke V; Aretz S; Friedl W; Buettner R; Mangold E; Propping P; Walldorf C
J Pathol; 2008 Jan; 214(1):10-6. PubMed ID: 17973250
[TBL] [Abstract][Full Text] [Related]
35. Evidence for heritable predisposition to epigenetic silencing of MLH1.
Chen H; Taylor NP; Sotamaa KM; Mutch DG; Powell MA; Schmidt AP; Feng S; Hampel HL; de la Chapelle A; Goodfellow PJ
Int J Cancer; 2007 Apr; 120(8):1684-8. PubMed ID: 17230510
[TBL] [Abstract][Full Text] [Related]
36. Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.
Niessen RC; Hofstra RM; Westers H; Ligtenberg MJ; Kooi K; Jager PO; de Groote ML; Dijkhuizen T; Olderode-Berends MJ; Hollema H; Kleibeuker JH; Sijmons RH
Genes Chromosomes Cancer; 2009 Aug; 48(8):737-44. PubMed ID: 19455606
[TBL] [Abstract][Full Text] [Related]
37. Aberrant DNA methylation in non-neoplastic gastric mucosa of H. Pylori infected patients and effect of eradication.
Perri F; Cotugno R; Piepoli A; Merla A; Quitadamo M; Gentile A; Pilotto A; Annese V; Andriulli A
Am J Gastroenterol; 2007 Jul; 102(7):1361-71. PubMed ID: 17509026
[TBL] [Abstract][Full Text] [Related]
38. The MLH1 -93 promoter variant influences gene expression.
Mei M; Liu D; Dong S; Ingvarsson S; Goodfellow PJ; Chen H
Cancer Epidemiol; 2010 Feb; 34(1):93-5. PubMed ID: 20060799
[TBL] [Abstract][Full Text] [Related]
39. Heritable germline epimutations in humans.
Horsthemke B
Nat Genet; 2007 May; 39(5):573-4; author reply 575-6. PubMed ID: 17460680
[No Abstract] [Full Text] [Related]
40. Microsatellite instability and MLH1 promoter methylation in human retinoblastoma.
Choy KW; Pang CP; Fan DS; Lee TC; Wang JH; Abramson DH; Lo KW; To KF; Yu CB; Beaverson KL; Cheung KF; Lam DS
Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3404-9. PubMed ID: 15452042
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
