225 related articles for article (PubMed ID: 21840902)
1. The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis.
Jemt E; Farge G; Bäckström S; Holmlund T; Gustafsson CM; Falkenberg M
Nucleic Acids Res; 2011 Nov; 39(21):9238-49. PubMed ID: 21840902
[TBL] [Abstract][Full Text] [Related]
2. The N-terminal domain of TWINKLE contributes to single-stranded DNA binding and DNA helicase activities.
Farge G; Holmlund T; Khvorostova J; Rofougaran R; Hofer A; Falkenberg M
Nucleic Acids Res; 2008 Feb; 36(2):393-403. PubMed ID: 18039713
[TBL] [Abstract][Full Text] [Related]
3. Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro.
Wanrooij S; Fusté JM; Farge G; Shi Y; Gustafsson CM; Falkenberg M
Proc Natl Acad Sci U S A; 2008 Aug; 105(32):11122-7. PubMed ID: 18685103
[TBL] [Abstract][Full Text] [Related]
4. Stimulation of Variant Forms of the Mitochondrial DNA Helicase Twinkle by the Mitochondrial Single-Stranded DNA-Binding Protein.
Rodrigues APC; Oliveira MT
Methods Mol Biol; 2021; 2281():313-322. PubMed ID: 33847968
[TBL] [Abstract][Full Text] [Related]
5. The accessory subunit B of DNA polymerase gamma is required for mitochondrial replisome function.
Farge G; Pham XH; Holmlund T; Khorostov I; Falkenberg M
Nucleic Acids Res; 2007; 35(3):902-11. PubMed ID: 17251196
[TBL] [Abstract][Full Text] [Related]
6. Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase.
Kaur P; Longley MJ; Pan H; Wang W; Countryman P; Wang H; Copeland WC
J Biol Chem; 2020 Apr; 295(17):5564-5576. PubMed ID: 32213598
[TBL] [Abstract][Full Text] [Related]
7. TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication.
Milenkovic D; Matic S; Kühl I; Ruzzenente B; Freyer C; Jemt E; Park CB; Falkenberg M; Larsson NG
Hum Mol Genet; 2013 May; 22(10):1983-93. PubMed ID: 23393161
[TBL] [Abstract][Full Text] [Related]
8. Oxidative DNA damage stalls the human mitochondrial replisome.
Stojkovič G; Makarova AV; Wanrooij PH; Forslund J; Burgers PM; Wanrooij S
Sci Rep; 2016 Jul; 6():28942. PubMed ID: 27364318
[TBL] [Abstract][Full Text] [Related]
9. TWINKLE and Other Human Mitochondrial DNA Helicases: Structure, Function and Disease.
Peter B; Falkenberg M
Genes (Basel); 2020 Apr; 11(4):. PubMed ID: 32283748
[TBL] [Abstract][Full Text] [Related]
10. In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication.
Miralles Fusté J; Shi Y; Wanrooij S; Zhu X; Jemt E; Persson Ö; Sabouri N; Gustafsson CM; Falkenberg M
PLoS Genet; 2014 Dec; 10(12):e1004832. PubMed ID: 25474639
[TBL] [Abstract][Full Text] [Related]
11. Reduced stimulation of recombinant DNA polymerase γ and mitochondrial DNA (mtDNA) helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA replication in animal cells.
Oliveira MT; Kaguni LS
J Biol Chem; 2011 Nov; 286(47):40649-58. PubMed ID: 21953457
[TBL] [Abstract][Full Text] [Related]
12. In Vitro Assays of TWINKLE Function.
Uhler JP; Alexandersson U; Falkenberg M
Methods Mol Biol; 2023; 2615():191-201. PubMed ID: 36807793
[TBL] [Abstract][Full Text] [Related]
13. Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.
Wanrooij S; Goffart S; Pohjoismäki JL; Yasukawa T; Spelbrink JN
Nucleic Acids Res; 2007; 35(10):3238-51. PubMed ID: 17452351
[TBL] [Abstract][Full Text] [Related]
14. DNA polymerase delta holoenzyme: action on single-stranded DNA and on double-stranded DNA in the presence of replicative DNA helicases.
Podust VN; Podust LM; Müller F; Hübscher U
Biochemistry; 1995 Apr; 34(15):5003-10. PubMed ID: 7711022
[TBL] [Abstract][Full Text] [Related]
15. Human mitochondrial DNA helicase TWINKLE is both an unwinding and annealing helicase.
Sen D; Nandakumar D; Tang GQ; Patel SS
J Biol Chem; 2012 Apr; 287(18):14545-56. PubMed ID: 22383523
[TBL] [Abstract][Full Text] [Related]
16. DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.
Bharti SK; Sommers JA; Zhou J; Kaplan DL; Spelbrink JN; Mergny JL; Brosh RM
J Biol Chem; 2014 Oct; 289(43):29975-93. PubMed ID: 25193669
[TBL] [Abstract][Full Text] [Related]
17. The Dictyostelium discoideum homologue of Twinkle, Twm1, is a mitochondrial DNA helicase, an active primase and promotes mitochondrial DNA replication.
Harman A; Barth C
BMC Mol Biol; 2018 Dec; 19(1):12. PubMed ID: 30563453
[TBL] [Abstract][Full Text] [Related]
18. Trypsin cleavage in the COOH terminus of the bacteriophage T4 gene 41 DNA helicase alters the primase-helicase activities of the T4 replication complex in vitro.
Richardson RW; Nossal NG
J Biol Chem; 1989 Mar; 264(8):4732-9. PubMed ID: 2466840
[TBL] [Abstract][Full Text] [Related]
19. Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.
Khan I; Crouch JD; Bharti SK; Sommers JA; Carney SM; Yakubovskaya E; Garcia-Diaz M; Trakselis MA; Brosh RM
J Biol Chem; 2016 Jul; 291(27):14324-14339. PubMed ID: 27226550
[TBL] [Abstract][Full Text] [Related]
20. The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ.
Johnson LC; Singh A; Patel SS
J Biol Chem; 2023 Jan; 299(1):102797. PubMed ID: 36528058
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
