BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 21840928)

  • 1. Reversible molecular pathology of skeletal muscle in spinal muscular atrophy.
    Mutsaers CA; Wishart TM; Lamont DJ; Riessland M; Schreml J; Comley LH; Murray LM; Parson SH; Lochmüller H; Wirth B; Talbot K; Gillingwater TH
    Hum Mol Genet; 2011 Nov; 20(22):4334-44. PubMed ID: 21840928
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.
    Martinez TL; Kong L; Wang X; Osborne MA; Crowder ME; Van Meerbeke JP; Xu X; Davis C; Wooley J; Goldhamer DJ; Lutz CM; Rich MM; Sumner CJ
    J Neurosci; 2012 Jun; 32(25):8703-15. PubMed ID: 22723710
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy.
    Wang ZB; Zhang X; Li XJ
    Cell Res; 2013 Mar; 23(3):378-93. PubMed ID: 23208423
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.
    Riessland M; Ackermann B; Förster A; Jakubik M; Hauke J; Garbes L; Fritzsche I; Mende Y; Blumcke I; Hahnen E; Wirth B
    Hum Mol Genet; 2010 Apr; 19(8):1492-506. PubMed ID: 20097677
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration.
    Arnold WD; Duque S; Iyer CC; Zaworski P; McGovern VL; Taylor SJ; von Herrmann KM; Kobayashi DT; Chen KS; Kolb SJ; Paushkin SV; Burghes AH
    PLoS One; 2016; 11(12):e0167077. PubMed ID: 27907033
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy.
    Murray LM; Lee S; Bäumer D; Parson SH; Talbot K; Gillingwater TH
    Hum Mol Genet; 2010 Feb; 19(3):420-33. PubMed ID: 19884170
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy.
    Boyer JG; Deguise MO; Murray LM; Yazdani A; De Repentigny Y; Boudreau-Larivière C; Kothary R
    Hum Mol Genet; 2014 Aug; 23(16):4249-59. PubMed ID: 24691550
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy.
    Bowerman M; Murray LM; Boyer JG; Anderson CL; Kothary R
    BMC Med; 2012 Mar; 10():24. PubMed ID: 22397316
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Severe SMA mice show organ impairment that cannot be rescued by therapy with the HDACi JNJ-26481585.
    Schreml J; Riessland M; Paterno M; Garbes L; Roßbach K; Ackermann B; Krämer J; Somers E; Parson SH; Heller R; Berkessel A; Sterner-Kock A; Wirth B
    Eur J Hum Genet; 2013 Jun; 21(6):643-52. PubMed ID: 23073311
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacologically induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset.
    Feng Z; Ling KK; Zhao X; Zhou C; Karp G; Welch EM; Naryshkin N; Ratni H; Chen KS; Metzger F; Paushkin S; Weetall M; Ko CP
    Hum Mol Genet; 2016 Mar; 25(5):964-75. PubMed ID: 26758873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
    Kannan A; Jiang X; He L; Ahmad S; Gangwani L
    Brain; 2020 Jan; 143(1):69-93. PubMed ID: 31828288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: applicability to preclinical therapy development for spinal muscular atrophy.
    Mattis VB; Butchbach ME; Lorson CL
    J Neurosci Methods; 2008 Oct; 175(1):36-43. PubMed ID: 18771690
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A cell-autonomous defect in skeletal muscle satellite cells expressing low levels of survival of motor neuron protein.
    Hayhurst M; Wagner AK; Cerletti M; Wagers AJ; Rubin LL
    Dev Biol; 2012 Aug; 368(2):323-34. PubMed ID: 22705478
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes.
    Rodriguez-Muela N; Parkhitko A; Grass T; Gibbs RM; Norabuena EM; Perrimon N; Singh R; Rubin LL
    J Clin Invest; 2018 Jul; 128(7):3008-3023. PubMed ID: 29672276
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models.
    Kim JK; Jha NN; Feng Z; Faleiro MR; Chiriboga CA; Wei-Lapierre L; Dirksen RT; Ko CP; Monani UR
    J Clin Invest; 2020 Mar; 130(3):1271-1287. PubMed ID: 32039917
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy.
    Deguise MO; De Repentigny Y; Tierney A; Beauvais A; Michaud J; Chehade L; Thabet M; Paul B; Reilly A; Gagnon S; Renaud JM; Kothary R
    EBioMedicine; 2020 May; 55():102750. PubMed ID: 32339936
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog.
    Ohuchi K; Funato M; Kato Z; Seki J; Kawase C; Tamai Y; Ono Y; Nagahara Y; Noda Y; Kameyama T; Ando S; Tsuruma K; Shimazawa M; Hara H; Kaneko H
    Stem Cells Transl Med; 2016 Feb; 5(2):152-63. PubMed ID: 26683872
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect.
    Gavrilina TO; McGovern VL; Workman E; Crawford TO; Gogliotti RG; DiDonato CJ; Monani UR; Morris GE; Burghes AH
    Hum Mol Genet; 2008 Apr; 17(8):1063-75. PubMed ID: 18178576
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition.
    Hauke J; Riessland M; Lunke S; Eyüpoglu IY; Blümcke I; El-Osta A; Wirth B; Hahnen E
    Hum Mol Genet; 2009 Jan; 18(2):304-17. PubMed ID: 18971205
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy.
    Millino C; Fanin M; Vettori A; Laveder P; Mostacciuolo ML; Angelini C; Lanfranchi G
    BMC Med; 2009 Apr; 7():14. PubMed ID: 19351384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.