197 related articles for article (PubMed ID: 21842375)
1. Epigenetic changes by zebularine leading to enhanced differentiation of human promyelocytic leukemia NB4 and KG1 cells.
Savickiene J; Treigyte G; Jonusiene V; Bruzaite R; Borutinskaite VV; Navakauskiene R
Mol Cell Biochem; 2012 Jan; 359(1-2):245-61. PubMed ID: 21842375
[TBL] [Abstract][Full Text] [Related]
2. Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells.
Savickiene J; Treigyte G; Borutinskaite VV; Navakauskiene R
Cell Mol Biol Lett; 2012 Dec; 17(4):501-25. PubMed ID: 22820861
[TBL] [Abstract][Full Text] [Related]
3. DNA methyltransferase inhibitor RG108 and histone deacetylase inhibitors cooperate to enhance NB4 cell differentiation and E-cadherin re-expression by chromatin remodelling.
Savickiene J; Treigyte G; Jazdauskaite A; Borutinskaite VV; Navakauskiene R
Cell Biol Int; 2012 Nov; 36(11):1067-78. PubMed ID: 22845560
[TBL] [Abstract][Full Text] [Related]
4. Response of retinoic acid-resistant KG1 cells to combination of retinoic acid with diverse histone deacetylase inhibitors.
Savickiene J; Treigyte G; Magnusson KE; Navakauskiene R
Ann N Y Acad Sci; 2009 Aug; 1171():321-33. PubMed ID: 19723072
[TBL] [Abstract][Full Text] [Related]
5. Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.
Billam M; Sobolewski MD; Davidson NE
Breast Cancer Res Treat; 2010 Apr; 120(3):581-92. PubMed ID: 19459041
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic and molecular mechanisms underlying the antileukemic activity of the histone deacetylase inhibitor belinostat in human acute promyelocytic leukemia cells.
Savickiene J; Treigyte G; Valiuliene G; Stirblyte I; Navakauskiene R
Anticancer Drugs; 2014 Sep; 25(8):938-49. PubMed ID: 24800886
[TBL] [Abstract][Full Text] [Related]
7. Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression.
Scott SA; Lakshimikuttysamma A; Sheridan DP; Sanche SE; Geyer CR; DeCoteau JF
Exp Hematol; 2007 Feb; 35(2):263-73. PubMed ID: 17258075
[TBL] [Abstract][Full Text] [Related]
8. C/EBPα and PU.1 are involved in distinct differentiation responses of acute promyelocytic leukemia HL-60 and NB4 cells via chromatin remodeling.
Savickiene J; Treigyte G; Vistartaite G; Tunaitis V; Magnusson KE; Navakauskiene R
Differentiation; 2011 Jan; 81(1):57-67. PubMed ID: 20864248
[TBL] [Abstract][Full Text] [Related]
9. Anti-leukemic effects of HDACi Belinostat and HMTi 3-Deazaneplanocin A on human acute promyelocytic leukemia cells.
Valiulienė G; Stirblytė I; Jasnauskaitė M; Borutinskaitė V; Navakauskienė R
Eur J Pharmacol; 2017 Mar; 799():143-153. PubMed ID: 28192098
[TBL] [Abstract][Full Text] [Related]
10. Zebularine enhances apoptosis of human osteosarcoma cells by suppressing methylation of ARHI.
Ye K; Wang S; Wang J; Han H; Ma B; Yang Y
Cancer Sci; 2016 Dec; 107(12):1851-1857. PubMed ID: 27685841
[TBL] [Abstract][Full Text] [Related]
11. Induction of differentiation of acute promyelocytic leukemia cells by a cytidine deaminase-resistant analogue of 1-beta-D-arabinofuranosylcytosine, 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytidine.
Niitsu N; Ishii Y; Matsuda A; Honma Y
Cancer Res; 2001 Jan; 61(1):178-85. PubMed ID: 11196157
[TBL] [Abstract][Full Text] [Related]
12. Epigenetic changes during hematopoietic cell granulocytic differentiation--comparative analysis of primary CD34+ cells, KG1 myeloid cells and mature neutrophils.
Navakauskienė R; Borutinskaitė VV; Treigytė G; Savickienė J; Matuzevičius D; Navakauskas D; Magnusson KE
BMC Cell Biol; 2014 Jan; 15():4. PubMed ID: 24443786
[TBL] [Abstract][Full Text] [Related]
13. Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase.
Benedetti L; Grignani F; Scicchitano BM; Jetten AM; Diverio D; Lo Coco F; Avvisati G; Gambacorti-Passerini C; Adamo S; Levin AA; Pelicci PG; Nervi C
Blood; 1996 Mar; 87(5):1939-50. PubMed ID: 8634442
[TBL] [Abstract][Full Text] [Related]
14. The expression of immediate early gene X-1 (IEX-1) is differentially induced by retinoic acids in NB4 and KG1 cells: possible implication in the distinct phenotype of retinoic acid-responsive and -resistant leukemic cells.
Arlt A; Minkenberg J; Kocs B; Grossmann M; Kruse ML; Fölsch UR; Schäfer H
Leukemia; 2004 Oct; 18(10):1646-55. PubMed ID: 15306824
[TBL] [Abstract][Full Text] [Related]
15. Belinostat, a potent HDACi, exerts antileukaemic effect in human acute promyelocytic leukaemia cells via chromatin remodelling.
Valiuliene G; Stirblyte I; Cicenaite D; Kaupinis A; Valius M; Navakauskiene R
J Cell Mol Med; 2015 Jul; 19(7):1742-55. PubMed ID: 25864732
[TBL] [Abstract][Full Text] [Related]
16. Histone modifications patterns in tissues and tumours from acute promyelocytic leukemia xenograft model in response to combined epigenetic therapy.
Valiulienė G; Treigytė G; Savickienė J; Matuzevičius D; Alksnė M; Jarašienė-Burinskaja R; Bukelskienė V; Navakauskas D; Navakauskienė R
Biomed Pharmacother; 2016 Apr; 79():62-70. PubMed ID: 27044813
[TBL] [Abstract][Full Text] [Related]
17. Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites.
Idres N; Benoît G; Flexor MA; Lanotte M; Chabot GG
Cancer Res; 2001 Jan; 61(2):700-5. PubMed ID: 11212271
[TBL] [Abstract][Full Text] [Related]
18. Euchromatic histone methyltransferase 2 inhibitor, BIX-01294, sensitizes human promyelocytic leukemia HL-60 and NB4 cells to growth inhibition and differentiation.
Savickiene J; Treigyte G; Stirblyte I; Valiuliene G; Navakauskiene R
Leuk Res; 2014 Jul; 38(7):822-9. PubMed ID: 24832370
[TBL] [Abstract][Full Text] [Related]
19. The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells.
Valiulienė G; Vitkevičienė A; Navakauskienė R
Eur J Pharmacol; 2020 Dec; 889():173641. PubMed ID: 33045196
[TBL] [Abstract][Full Text] [Related]
20. Effect of Zebularine in Comparison to and in Combination with Trichostatin A on CIP/KIP Family (p21Cip1/Waf1/Sdi1, p27Kip1, and p57Kip2), DNMTs (DNMT1, DNMT3a, and DNMT3b), Class I HDACs (HDACs 1, 2, 3) and Class II HDACs (HDACs 4, 5, 6) Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Colon Cancer LS 174T Cell Line.
Sanaei M; Kavoosi F
Asian Pac J Cancer Prev; 2020 Jul; 21(7):2131-2139. PubMed ID: 32711442
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]