These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 21843937)

  • 41. Discovery of N-(1-adamantyl)-2-(4-alkylpiperazin-1-yl)acetamide derivatives as T-type calcium channel (Cav3.2) inhibitors.
    Giordanetto F; Knerr L; Selmi N; Llinàs A; Lindqvist A; Wang QD; Ståhlberg P; Thorstensson F; Ullah V; Nilsson K; O'Mahony G; Högberg G; Lindhardt E; Strand A; Duker G
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5557-61. PubMed ID: 21782423
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Positive allosteric interaction of structurally diverse T-type calcium channel antagonists.
    Uebele VN; Nuss CE; Fox SV; Garson SL; Cristescu R; Doran SM; Kraus RL; Santarelli VP; Li Y; Barrow JC; Yang ZQ; Schlegel KA; Rittle KE; Reger TS; Bednar RA; Lemaire W; Mullen FA; Ballard JE; Tang C; Dai G; McManus OB; Koblan KS; Renger JJ
    Cell Biochem Biophys; 2009; 55(2):81-93. PubMed ID: 19582593
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Blockade of T-type voltage-dependent Ca2+ channels by benidipine, a dihydropyridine calcium channel blocker, inhibits aldosterone production in human adrenocortical cell line NCI-H295R.
    Akizuki O; Inayoshi A; Kitayama T; Yao K; Shirakura S; Sasaki K; Kusaka H; Matsubara M
    Eur J Pharmacol; 2008 Apr; 584(2-3):424-34. PubMed ID: 18331727
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Cardiovascular characterization of pyrrolo[2,1-d][1,5]benzothiazepine derivatives binding selectively to the peripheral-type benzodiazepine receptor (PBR): from dual PBR affinity and calcium antagonist activity to novel and selective calcium entry blockers.
    Campiani G; Fiorini I; De Filippis MP; Ciani SM; Garofalo A; Nacci V; Giorgi G; Sega A; Botta M; Chiarini A; Budriesi R; Bruni G; Romeo MR; Manzoni C; Mennini T
    J Med Chem; 1996 Jul; 39(15):2922-38. PubMed ID: 8709127
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Synthesis and SAR of 1,2-trans-(1-hydroxy-3-phenylprop-1-yl)cyclopentane carboxamide derivatives, a new class of sodium channel blockers.
    Ok D; Li C; Abbadie C; Felix JP; Fisher MH; Garcia ML; Kaczorowski GJ; Lyons KA; Martin WJ; Priest BT; Smith MM; Williams BS; Wyvratt MJ; Parsons WH
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1358-61. PubMed ID: 16337121
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Hyperalgesia induced by spinal and peripheral hydrogen sulfide: evidence for involvement of Cav3.2 T-type calcium channels.
    Maeda Y; Aoki Y; Sekiguchi F; Matsunami M; Takahashi T; Nishikawa H; Kawabata A
    Pain; 2009 Mar; 142(1-2):127-32. PubMed ID: 19167819
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Discovery of N-[[1-[2-(tert-butylcarbamoylamino)ethyl]-4-(hydroxymethyl)-4-piperidyl]methyl]-3,5-dichloro-benzamide as a selective T-type calcium channel (Cav3.2) inhibitor.
    Giordanetto F; Wållberg A; Knerr L; Selmi N; Ullah V; Thorstensson F; Lindelöf Å; Karlsson S; Nikitidis G; Llinas A; Wang QD; Lindqvist A; Högberg G; Lindhardt E; Åstrand A; Duker G
    Bioorg Med Chem Lett; 2013 Jan; 23(1):119-24. PubMed ID: 23200256
    [TBL] [Abstract][Full Text] [Related]  

  • 48. T-type Ca2+ channel blockers suppress the growth of human cancer cells.
    Heo JH; Seo HN; Choe YJ; Kim S; Oh CR; Kim YD; Rhim H; Choo DJ; Kim J; Lee JY
    Bioorg Med Chem Lett; 2008 Jul; 18(14):3899-901. PubMed ID: 18585035
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Structural hybridization of pyrrolidine-based T-type calcium channel inhibitors and exploration of their analgesic effects in a neuropathic pain model.
    Son WS; Jeong KS; Lim SM; Pae AN
    Bioorg Med Chem Lett; 2019 May; 29(10):1168-1172. PubMed ID: 30928197
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis and biological evaluation of novel N3-substituted dihydropyrimidine derivatives as T-type calcium channel blockers and their efficacy as analgesics in mouse models of inflammatory pain.
    Teleb M; Zhang FX; Huang J; Gadotti VM; Farghaly AM; AboulWafa OM; Zamponi GW; Fahmy H
    Bioorg Med Chem; 2017 Mar; 25(6):1926-1938. PubMed ID: 28233679
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice.
    Sekiguchi F; Fujita T; Deguchi T; Yamaoka S; Tomochika K; Tsubota M; Ono S; Horaguchi Y; Ichii M; Ichikawa M; Ueno Y; Koike N; Tanino T; Nguyen HD; Okada T; Nishikawa H; Yoshida S; Ohkubo T; Toyooka N; Murata K; Matsuda H; Kawabata A
    Neuropharmacology; 2018 Aug; 138():232-244. PubMed ID: 29913186
    [TBL] [Abstract][Full Text] [Related]  

  • 52. 5beta-reduced neuroactive steroids are novel voltage-dependent blockers of T-type Ca2+ channels in rat sensory neurons in vitro and potent peripheral analgesics in vivo.
    Todorovic SM; Pathirathna S; Brimelow BC; Jagodic MM; Ko SH; Jiang X; Nilsson KR; Zorumski CF; Covey DF; Jevtovic-Todorovic V
    Mol Pharmacol; 2004 Nov; 66(5):1223-35. PubMed ID: 15280444
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Newer N-phthaloyl GABA derivatives with antiallodynic and antihyperalgesic activities in both sciatic nerve and spinal nerve ligation models of neuropathic pain.
    Yogeeswari P; Ragavendran JV; Sriram D; Kavya R; Vanitha K; Neelakantan H
    Pharmacology; 2008; 81(1):21-31. PubMed ID: 17785996
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Synthesis and biological evaluation of novel T-type calcium channel blockers.
    Choi JY; Seo HN; Lee MJ; Park SJ; Park SJ; Jeon JY; Kang JH; Pae AN; Rhim H; Lee JY
    Bioorg Med Chem Lett; 2007 Jan; 17(2):471-5. PubMed ID: 17064894
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Growth inhibition of human cancer cells in vitro by T-type calcium channel blockers.
    Lee JY; Park SJ; Park SJ; Lee MJ; Rhim H; Seo SH; Kim KS
    Bioorg Med Chem Lett; 2006 Oct; 16(19):5014-7. PubMed ID: 16876410
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Discovery and evaluation of selective N-type calcium channel blockers: 6-unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives.
    Yamamoto T; Niwa S; Tokumasu M; Onishi T; Ohno S; Hagihara M; Koganei H; Fujita S; Takeda T; Saitou Y; Iwayama S; Takahara A; Iwata S; Shoji M
    Bioorg Med Chem Lett; 2012 Jun; 22(11):3639-42. PubMed ID: 22560585
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Structure-activity relationship study of 1,4-dihydropyridine derivatives blocking N-type calcium channels.
    Yamamoto T; Niwa S; Ohno S; Onishi T; Matsueda H; Koganei H; Uneyama H; Fujita S; Takeda T; Kito M; Ono Y; Saitou Y; Takahara A; Iwata S; Shoji M
    Bioorg Med Chem Lett; 2006 Feb; 16(4):798-802. PubMed ID: 16309909
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors.
    Pajouhesh H; Feng ZP; Ding Y; Zhang L; Pajouhesh H; Morrison JL; Belardetti F; Tringham E; Simonson E; Vanderah TW; Porreca F; Zamponi GW; Mitscher LA; Snutch TP
    Bioorg Med Chem Lett; 2010 Feb; 20(4):1378-83. PubMed ID: 20117000
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Novel potent and selective calcium-release-activated calcium (CRAC) channel inhibitors. Part 1: synthesis and inhibitory activity of 5-(1-methyl-3-trifluoromethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamides.
    Yonetoku Y; Kubota H; Okamoto Y; Toyoshima A; Funatsu M; Ishikawa J; Takeuchi M; Ohta M; Tsukamoto S
    Bioorg Med Chem; 2006 Jul; 14(14):4750-60. PubMed ID: 16580212
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Investigation into the structure-activity relationship of novel concentration dependent, dual action T-type calcium channel agonists/antagonists.
    McCalmont WF; Patterson JR; Lindenmuth MA; Heady TN; Haverstick DM; Gray LS; Macdonald TL
    Bioorg Med Chem; 2005 Jun; 13(11):3821-39. PubMed ID: 15863008
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.