These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 21844184)

  • 1. Cyclin D1 and cdk4 mediate development of neurologically destructive oligodendroglioma.
    Ciznadija D; Liu Y; Pyonteck SM; Holland EC; Koff A
    Cancer Res; 2011 Oct; 71(19):6174-83. PubMed ID: 21844184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1).
    Liu Y; Yeh N; Zhu XH; Leversha M; Cordon-Cardo C; Ghossein R; Singh B; Holland E; Koff A
    EMBO J; 2007 Nov; 26(22):4683-93. PubMed ID: 17948060
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Requirement for CDK4 kinase function in breast cancer.
    Yu Q; Sicinska E; Geng Y; Ahnström M; Zagozdzon A; Kong Y; Gardner H; Kiyokawa H; Harris LN; Stål O; Sicinski P
    Cancer Cell; 2006 Jan; 9(1):23-32. PubMed ID: 16413469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ara-c induces cell cycle G1/S arrest by inducing upregulation of the INK4 family gene or directly inhibiting the formation of the cell cycle-dependent complex CDK4/cyclin D1.
    Sun F; Li N; Tong X; Zeng J; He S; Gai T; Bai Y; Liu L; Lu K; Shen J; Han M; Lu C; Dai F
    Cell Cycle; 2019 Sep; 18(18):2293-2306. PubMed ID: 31322047
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RN181 is a tumour suppressor in gastric cancer by regulation of the ERK/MAPK-cyclin D1/CDK4 pathway.
    Wang S; Wang X; Gao Y; Peng Y; Dong N; Xie Q; Zhang X; Wu Y; Li M; Li JL
    J Pathol; 2019 Jun; 248(2):204-216. PubMed ID: 30714150
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mouse mammary hyperplasias and neoplasias exhibit different patterns of cyclins D1 and D2 binding to cdk4.
    Said TK; Luo L; Medina D
    Carcinogenesis; 1995 Oct; 16(10):2507-13. PubMed ID: 7586159
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity.
    Fatrai S; Elghazi L; Balcazar N; Cras-Méneur C; Krits I; Kiyokawa H; Bernal-Mizrachi E
    Diabetes; 2006 Feb; 55(2):318-25. PubMed ID: 16443763
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis.
    Jirawatnotai S; Sharma S; Michowski W; Suktitipat B; Geng Y; Quackenbush J; Elias JE; Gygi SP; Wang YE; Sicinski P
    Cell Cycle; 2014; 13(18):2889-900. PubMed ID: 25486477
    [TBL] [Abstract][Full Text] [Related]  

  • 9. miR-1 suppresses the growth of esophageal squamous cell carcinoma in vivo and in vitro through the downregulation of MET, cyclin D1 and CDK4 expression.
    Jiang S; Zhao C; Yang X; Li X; Pan Q; Huang H; Wen X; Shan H; Li Q; Du Y; Zhao Y
    Int J Mol Med; 2016 Jul; 38(1):113-22. PubMed ID: 27247259
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: Effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression.
    Grillo M; Bott MJ; Khandke N; McGinnis JP; Miranda M; Meyyappan M; Rosfjord EC; Rabindran SK
    Breast Cancer Res Treat; 2006 Jan; 95(2):185-94. PubMed ID: 16319987
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of Cell Cyle Regulators Cyclin D1, CDK4, and p53 in Knee Osteoarthritis.
    Zhu X; Yang S; Lin W; Wang L; Ying J; Ding Y; Chen X
    Genet Test Mol Biomarkers; 2016 Sep; 20(9):529-34. PubMed ID: 27391794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the AKT/GSK3β/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy.
    Shimura T; Kakuda S; Ochiai Y; Kuwahara Y; Takai Y; Fukumoto M
    Int J Radiat Oncol Biol Phys; 2011 Jun; 80(2):540-8. PubMed ID: 21398050
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture.
    Paternot S; Dumont JE; Roger PP
    Mol Endocrinol; 2006 Dec; 20(12):3279-92. PubMed ID: 16916940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vitex rotundifolia Fruit Suppresses the Proliferation of Human Colorectal Cancer Cells through Down-regulation of Cyclin D1 and CDK4 via Proteasomal-Dependent Degradation and Transcriptional Inhibition.
    Song HM; Park GH; Park SB; Kim HS; Son HJ; Um Y; Jeong JB
    Am J Chin Med; 2018; 46(1):191-207. PubMed ID: 29298515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.
    Aggarwal P; Vaites LP; Kim JK; Mellert H; Gurung B; Nakagawa H; Herlyn M; Hua X; Rustgi AK; McMahon SB; Diehl JA
    Cancer Cell; 2010 Oct; 18(4):329-40. PubMed ID: 20951943
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.
    Lukas J; Bartkova J; Rohde M; Strauss M; Bartek J
    Mol Cell Biol; 1995 May; 15(5):2600-11. PubMed ID: 7739541
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chemical transformation of mouse liver cells results in altered cyclin D-CDK protein complexes.
    Gonzales AJ; Goldsworthy TL; Fox TR
    Carcinogenesis; 1998 Jun; 19(6):1093-102. PubMed ID: 9667749
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of MAPK and Cyclin D1/CDK4 in Malignant Transformation of Human Embryonic Lung Fibroblasts Induced by Silica and Benzopyrene.
    Wang H; Xiao S; Tang Y; Han K; Zhang Z; Jin Y; Shen F
    Asian Pac J Cancer Prev; 2020 Feb; 21(2):295-300. PubMed ID: 32102502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclin D1 expression in normal oligodendroglia and microglia cells: its use in the differential diagnosis of oligodendrogliomas.
    Bosone I; Cavalla P; Chiadò-Piat L; Vito ND; Schiffer D
    Neuropathology; 2001 Sep; 21(3):155-61. PubMed ID: 11666011
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.
    Larrea MD; Liang J; Da Silva T; Hong F; Shao SH; Han K; Dumont D; Slingerland JM
    Mol Cell Biol; 2008 Oct; 28(20):6462-72. PubMed ID: 18710949
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.