297 related articles for article (PubMed ID: 21844199)
1. c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice.
Win S; Than TA; Han D; Petrovic LM; Kaplowitz N
J Biol Chem; 2011 Oct; 286(40):35071-8. PubMed ID: 21844199
[TBL] [Abstract][Full Text] [Related]
2. c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src.
Win S; Than TA; Min RW; Aghajan M; Kaplowitz N
Hepatology; 2016 Jun; 63(6):1987-2003. PubMed ID: 26845758
[TBL] [Abstract][Full Text] [Related]
3. The role of MAP2 kinases and p38 kinase in acute murine liver injury models.
Zhang J; Min RWM; Le K; Zhou S; Aghajan M; Than TA; Win S; Kaplowitz N
Cell Death Dis; 2017 Jun; 8(6):e2903. PubMed ID: 28661486
[TBL] [Abstract][Full Text] [Related]
4. Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.
Win S; Than TA; Le BH; García-Ruiz C; Fernandez-Checa JC; Kaplowitz N
J Hepatol; 2015 Jun; 62(6):1367-74. PubMed ID: 25666017
[TBL] [Abstract][Full Text] [Related]
5. Antcin H Protects Against Acute Liver Injury Through Disruption of the Interaction of c-Jun-N-Terminal Kinase with Mitochondria.
Huo Y; Win S; Than TA; Yin S; Ye M; Hu H; Kaplowitz N
Antioxid Redox Signal; 2017 Feb; 26(5):207-220. PubMed ID: 27596680
[TBL] [Abstract][Full Text] [Related]
6. JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death.
Win S; Than TA; Fernandez-Checa JC; Kaplowitz N
Cell Death Dis; 2014 Jan; 5(1):e989. PubMed ID: 24407242
[TBL] [Abstract][Full Text] [Related]
7. Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury.
Win S; Min RW; Chen CQ; Zhang J; Chen Y; Li M; Suzuki A; Abdelmalek MF; Wang Y; Aghajan M; Aung FW; Diehl AM; Davis RJ; Than TA; Kaplowitz N
J Clin Invest; 2019 Dec; 129(12):5278-5293. PubMed ID: 31487267
[TBL] [Abstract][Full Text] [Related]
8. Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.
Shinohara M; Ybanez MD; Win S; Than TA; Jain S; Gaarde WA; Han D; Kaplowitz N
J Biol Chem; 2010 Mar; 285(11):8244-55. PubMed ID: 20061376
[TBL] [Abstract][Full Text] [Related]
9. Hepatic Mitochondrial SAB Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis.
Win S; Min RWM; Zhang J; Kanel G; Wanken B; Chen Y; Li M; Wang Y; Suzuki A; Aung FWM; Murray SF; Aghajan M; Than TA; Kaplowitz N
Hepatology; 2021 Dec; 74(6):3127-3145. PubMed ID: 34331779
[TBL] [Abstract][Full Text] [Related]
10. c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.
Saito C; Lemasters JJ; Jaeschke H
Toxicol Appl Pharmacol; 2010 Jul; 246(1-2):8-17. PubMed ID: 20423716
[TBL] [Abstract][Full Text] [Related]
11. Nrf2-mediated liver protection by esculentoside A against acetaminophen toxicity through the AMPK/Akt/GSK3β pathway.
Wang L; Zhang S; Cheng H; Lv H; Cheng G; Ci X
Free Radic Biol Med; 2016 Dec; 101():401-412. PubMed ID: 27836781
[TBL] [Abstract][Full Text] [Related]
12. c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.
Gunawan BK; Liu ZX; Han D; Hanawa N; Gaarde WA; Kaplowitz N
Gastroenterology; 2006 Jul; 131(1):165-78. PubMed ID: 16831600
[TBL] [Abstract][Full Text] [Related]
13. The MAP2K4/JNK/c-Jun Signaling Pathway Plays A Key Role In Dexmedetomidine Protection Against Acetaminophen-Induced Liver Toxicity.
Chou AH; Liao CC; Lee HC; Liou JT; Liu FC
Drug Des Devel Ther; 2019; 13():3887-3898. PubMed ID: 31814709
[TBL] [Abstract][Full Text] [Related]
14. Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.
Du K; Ramachandran A; Weemhoff JL; Chavan H; Xie Y; Krishnamurthy P; Jaeschke H
Toxicol Sci; 2016 Dec; 154(2):214-226. PubMed ID: 27562556
[TBL] [Abstract][Full Text] [Related]
15. Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation.
Nakagawa H; Maeda S; Hikiba Y; Ohmae T; Shibata W; Yanai A; Sakamoto K; Ogura K; Noguchi T; Karin M; Ichijo H; Omata M
Gastroenterology; 2008 Oct; 135(4):1311-21. PubMed ID: 18700144
[TBL] [Abstract][Full Text] [Related]
16. Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver.
Hu J; Ramshesh VK; McGill MR; Jaeschke H; Lemasters JJ
Toxicol Sci; 2016 Mar; 150(1):204-15. PubMed ID: 26721299
[TBL] [Abstract][Full Text] [Related]
17. Astaxanthin pretreatment attenuates acetaminophen-induced liver injury in mice.
Zhang J; Zhang S; Bi J; Gu J; Deng Y; Liu C
Int Immunopharmacol; 2017 Apr; 45():26-33. PubMed ID: 28152447
[TBL] [Abstract][Full Text] [Related]
18. Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury.
Xie Y; Ramachandran A; Breckenridge DG; Liles JT; Lebofsky M; Farhood A; Jaeschke H
Toxicol Appl Pharmacol; 2015 Jul; 286(1):1-9. PubMed ID: 25818599
[TBL] [Abstract][Full Text] [Related]
19. The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.
Ramachandran A; Lebofsky M; Weinman SA; Jaeschke H
Toxicol Appl Pharmacol; 2011 Mar; 251(3):226-33. PubMed ID: 21241727
[TBL] [Abstract][Full Text] [Related]
20. A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria.
Wiltshire C; Matsushita M; Tsukada S; Gillespie DA; May GH
Biochem J; 2002 Nov; 367(Pt 3):577-85. PubMed ID: 12167088
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
