254 related articles for article (PubMed ID: 21846118)
21. Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment.
Yuan J; Lovejoy DB; Richardson DR
Blood; 2004 Sep; 104(5):1450-8. PubMed ID: 15150082
[TBL] [Abstract][Full Text] [Related]
22. Iron chelators of the dipyridylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity.
Bernhardt PV; Sharpe PC; Islam M; Lovejoy DB; Kalinowski DS; Richardson DR
J Med Chem; 2009 Jan; 52(2):407-15. PubMed ID: 19090766
[TBL] [Abstract][Full Text] [Related]
23. Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells.
Ohui K; Stepanenko I; Besleaga I; Babak MV; Stafi R; Darvasiova D; Giester G; Pósa V; Enyedy EA; Vegh D; Rapta P; Ang WH; Popović-Bijelić A; Arion VB
Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32961653
[TBL] [Abstract][Full Text] [Related]
24. Novel 2-pyridinecarboxaldehyde thiosemicarbazones Ga(III) complexes with a high antiproliferative activity by promoting apoptosis and inhibiting cell cycle.
Qi J; Deng J; Qian K; Tian L; Li J; He K; Huang X; Cheng Z; Zheng Y; Wang Y
Eur J Med Chem; 2017 Jul; 134():34-42. PubMed ID: 28395152
[TBL] [Abstract][Full Text] [Related]
25. Kinetico-mechanistic studies on methemoglobin generation by biologically active thiosemicarbazone iron(III) complexes.
Basha MT; Bordini J; Richardson DR; Martinez M; Bernhardt PV
J Inorg Biochem; 2016 Sep; 162():326-333. PubMed ID: 27079328
[TBL] [Abstract][Full Text] [Related]
26. Intracellular reduction/activation of a disulfide switch in thiosemicarbazone iron chelators.
Akam EA; Chang TM; Astashkin AV; Tomat E
Metallomics; 2014 Oct; 6(10):1905-12. PubMed ID: 25100578
[TBL] [Abstract][Full Text] [Related]
27. Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.
Chaston TB; Watts RN; Yuan J; Richardson DR
Clin Cancer Res; 2004 Nov; 10(21):7365-74. PubMed ID: 15534113
[TBL] [Abstract][Full Text] [Related]
28. Anticancer activity of the thiosemicarbazones that are based on di-2-pyridine ketone and quinoline moiety.
Mrozek-Wilczkiewicz A; Malarz K; Rejmund M; Polanski J; Musiol R
Eur J Med Chem; 2019 Jun; 171():180-194. PubMed ID: 30921758
[TBL] [Abstract][Full Text] [Related]
29. Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells.
González-Bártulos M; Aceves-Luquero C; Qualai J; Cussó O; Martínez MA; Fernández de Mattos S; Menéndez JA; Villalonga P; Costas M; Ribas X; Massaguer A
PLoS One; 2015; 10(9):e0137800. PubMed ID: 26368127
[TBL] [Abstract][Full Text] [Related]
30. Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands.
Bernhardt PV; Wilson GJ; Sharpe PC; Kalinowski DS; Richardson DR
J Biol Inorg Chem; 2008 Jan; 13(1):107-19. PubMed ID: 17899222
[TBL] [Abstract][Full Text] [Related]
31. Cytotoxic and apoptotic effects of ternary silver(i) complexes bearing 2-formylpyridine thiosemicarbazones and 1,10-phenanthroline.
Silva DES; Becceneri AB; Solcia MC; Santiago JVB; Moreira MB; Gomes Neto JA; Pavan FR; Cominetti MR; Pereira JCM; Netto AVG
Dalton Trans; 2020 Apr; 49(16):5264-5275. PubMed ID: 32242564
[TBL] [Abstract][Full Text] [Related]
32. Synthesis, crystal structure and biological evaluation of a main group seven-coordinated bismuth(III) complex with 2-acetylpyridine N4-phenylthiosemicarbazone.
Li YK; Yang M; Li MX; Yu H; Wu HC; Xie SQ
Bioorg Med Chem Lett; 2013 Apr; 23(8):2288-92. PubMed ID: 23489627
[TBL] [Abstract][Full Text] [Related]
33. Investigation of the cytotoxic implications of metal chelators against melanoma and approaches to improve the cytotoxicity profiles of metal coordinating agents.
Akladios FN; Andrew SD; Parkinson CJ
Biometals; 2016 Oct; 29(5):789-805. PubMed ID: 27389037
[TBL] [Abstract][Full Text] [Related]
34. Thiosemicarbazone Cu(II) and Zn(II) complexes as potential anticancer agents: syntheses, crystal structure, DNA cleavage, cytotoxicity and apoptosis induction activity.
Shao J; Ma ZY; Li A; Liu YH; Xie CZ; Qiang ZY; Xu JY
J Inorg Biochem; 2014 Jul; 136():13-23. PubMed ID: 24690556
[TBL] [Abstract][Full Text] [Related]
35. A series of alpha-heterocyclic carboxaldehyde thiosemicarbazones inhibit topoisomerase IIalpha catalytic activity.
Huang H; Chen Q; Ku X; Meng L; Lin L; Wang X; Zhu C; Wang Y; Chen Z; Li M; Jiang H; Chen K; Ding J; Liu H
J Med Chem; 2010 Apr; 53(8):3048-64. PubMed ID: 20353152
[TBL] [Abstract][Full Text] [Related]
36. Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure-Activity Relationship Study.
Yellol J; Pérez SA; Buceta A; Yellol G; Donaire A; Szumlas P; Bednarski PJ; Makhloufi G; Janiak C; Espinosa A; Ruiz J
J Med Chem; 2015 Sep; 58(18):7310-27. PubMed ID: 26313136
[TBL] [Abstract][Full Text] [Related]
37. Effects of polar substituents on the biological activity of thiosemicarbazone metal complexes.
Bisceglie F; Tavone M; Mussi F; Azzoni S; Montalbano S; Franzoni S; Tarasconi P; Buschini A; Pelosi G
J Inorg Biochem; 2018 Feb; 179():60-70. PubMed ID: 29175629
[TBL] [Abstract][Full Text] [Related]
38. Impact of Stepwise NH2-Methylation of Triapine on the Physicochemical Properties, Anticancer Activity, and Resistance Circumvention.
Kowol CR; Miklos W; Pfaff S; Hager S; Kallus S; Pelivan K; Kubanik M; Enyedy ÉA; Berger W; Heffeter P; Keppler BK
J Med Chem; 2016 Jul; 59(14):6739-52. PubMed ID: 27336684
[TBL] [Abstract][Full Text] [Related]
39. Increased generation of intracellular reactive oxygen species initiates selective cytotoxicity against the MCF-7 cell line resultant from redox active combination therapy using copper-thiosemicarbazone complexes.
Akladios FN; Andrew SD; Parkinson CJ
J Biol Inorg Chem; 2016 Jun; 21(3):407-19. PubMed ID: 26951232
[TBL] [Abstract][Full Text] [Related]
40. Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect.
Quach P; Gutierrez E; Basha MT; Kalinowski DS; Sharpe PC; Lovejoy DB; Bernhardt PV; Jansson PJ; Richardson DR
Mol Pharmacol; 2012 Jul; 82(1):105-14. PubMed ID: 22508546
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]