BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 21846719)

  • 1. Liver-specific inducible nitric-oxide synthase expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice.
    Shinozaki S; Choi CS; Shimizu N; Yamada M; Kim M; Zhang T; Shiota G; Dong HH; Kim YB; Kaneki M
    J Biol Chem; 2011 Oct; 286(40):34959-75. PubMed ID: 21846719
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inducible nitric oxide synthase deficiency ameliorates skeletal muscle insulin resistance but does not alter unexpected lower blood glucose levels after burn injury in C57BL/6 mice.
    Sugita M; Sugita H; Kim M; Mao J; Yasuda Y; Habiro M; Shinozaki S; Yasuhara S; Shimizu N; Martyn JA; Kaneki M
    Metabolism; 2012 Jan; 61(1):127-36. PubMed ID: 21816442
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inducible nitric oxide synthase induction underlies lipid-induced hepatic insulin resistance in mice: potential role of tyrosine nitration of insulin signaling proteins.
    Charbonneau A; Marette A
    Diabetes; 2010 Apr; 59(4):861-71. PubMed ID: 20103705
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice.
    Fujimoto M; Shimizu N; Kunii K; Martyn JA; Ueki K; Kaneki M
    Diabetes; 2005 May; 54(5):1340-8. PubMed ID: 15855318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRbeta/IRS-1 and Akt.
    Carvalho-Filho MA; Ropelle ER; Pauli RJ; Cintra DE; Tsukumo DM; Silveira LR; Curi R; Carvalheira JB; Velloso LA; Saad MJ
    Diabetologia; 2009 Nov; 52(11):2425-34. PubMed ID: 19730809
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.
    Carvalho-Filho MA; Ueno M; Carvalheira JB; Velloso LA; Saad MJ
    Am J Physiol Endocrinol Metab; 2006 Sep; 291(3):E476-82. PubMed ID: 16638822
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.
    Tanioka T; Tamura Y; Fukaya M; Shinozaki S; Mao J; Kim M; Shimizu N; Kitamura T; Kaneki M
    J Biol Chem; 2011 Aug; 286(33):29388-29396. PubMed ID: 21700708
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance.
    Sugita H; Kaneki M; Tokunaga E; Sugita M; Koike C; Yasuhara S; Tompkins RG; Martyn JA
    Am J Physiol Endocrinol Metab; 2002 Feb; 282(2):E386-94. PubMed ID: 11788371
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
    Sajan MP; Ivey RA; Lee MC; Farese RV
    J Lipid Res; 2015 Jan; 56(1):70-80. PubMed ID: 25395359
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes.
    Valverde AM; Burks DJ; Fabregat I; Fisher TL; Carretero J; White MF; Benito M
    Diabetes; 2003 Sep; 52(9):2239-48. PubMed ID: 12941762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells.
    Sugita H; Fujimoto M; Yasukawa T; Shimizu N; Sugita M; Yasuhara S; Martyn JA; Kaneki M
    J Biol Chem; 2005 Apr; 280(14):14203-11. PubMed ID: 15805118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
    Liu TY; Shi CX; Gao R; Sun HJ; Xiong XQ; Ding L; Chen Q; Li YH; Wang JJ; Kang YM; Zhu GQ
    Clin Sci (Lond); 2015 Nov; 129(10):839-50. PubMed ID: 26201094
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Voluntary Exercise Can Ameliorate Insulin Resistance by Reducing iNOS-Mediated S-Nitrosylation of Akt in the Liver in Obese Rats.
    Tsuzuki T; Shinozaki S; Nakamoto H; Kaneki M; Goto S; Shimokado K; Kobayashi H; Naito H
    PLoS One; 2015; 10(7):e0132029. PubMed ID: 26172834
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of Mig-6 in hepatic glucose metabolism.
    Yoo JY; Kim TH; Kong S; Lee JH; Choi W; Kim KS; Kim HJ; Jeong JW; Ku BJ
    J Diabetes; 2016 Jan; 8(1):86-97. PubMed ID: 25594850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss.
    Marinho R; Ropelle ER; Cintra DE; De Souza CT; Da Silva AS; Bertoli FC; Colantonio E; D'Almeida V; Pauli JR
    J Cell Physiol; 2012 Jul; 227(7):2917-26. PubMed ID: 21938726
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deficiency of inducible nitric oxide synthase attenuates immobilization-induced skeletal muscle atrophy in mice.
    Bae SK; Cha HN; Ju TJ; Kim YW; Kim HS; Kim YD; Dan JM; Kim JY; Kim SD; Park SY
    J Appl Physiol (1985); 2012 Jul; 113(1):114-23. PubMed ID: 22518831
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glycogen synthase kinase 3 regulates IL-1β mediated iNOS expression in hepatocytes by down-regulating c-Jun.
    Lakshmanan J; Zhang B; Nweze IC; Du Y; Harbrecht BG
    J Cell Biochem; 2015 Jan; 116(1):133-41. PubMed ID: 25160751
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.
    Dallaire P; Bellmann K; Laplante M; Gélinas S; Centeno-Baez C; Penfornis P; Peyot ML; Latour MG; Lamontagne J; Trujillo ME; Scherer PE; Prentki M; Deshaies Y; Marette A
    Diabetes; 2008 Aug; 57(8):1999-2011. PubMed ID: 18458147
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nitric oxide inhibits the proliferation and invasion of pancreatic cancer cells through degradation of insulin receptor substrate-1 protein.
    Sugita H; Kaneki M; Furuhashi S; Hirota M; Takamori H; Baba H
    Mol Cancer Res; 2010 Aug; 8(8):1152-63. PubMed ID: 20663861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans.
    Sajan MP; Ivey RA; Farese RV
    Metabolism; 2015 Nov; 64(11):1454-65. PubMed ID: 26386696
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.