BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 21849623)

  • 1. Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys.
    Uehara S; Murayama N; Nakanishi Y; Zeldin DC; Yamazaki H; Uno Y
    J Pharmacol Exp Ther; 2011 Nov; 339(2):654-61. PubMed ID: 21849623
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys.
    Uehara S; Murayama N; Nakanishi Y; Nakamura C; Hashizume T; Zeldin DC; Yamazaki H; Uno Y
    Xenobiotica; 2014 Sep; 44(9):769-74. PubMed ID: 24593267
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of p450 enzymes between cynomolgus monkeys and humans: p450 identities, protein contents, kinetic parameters, and potential for inhibitory profiles.
    Emoto C; Yoda N; Uno Y; Iwasaki K; Umehara K; Kashiyama E; Yamazaki H
    Curr Drug Metab; 2013 Feb; 14(2):239-52. PubMed ID: 22963393
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
    Bullock P; Pearce R; Draper A; Podval J; Bracken W; Veltman J; Thomas P; Parkinson A
    Drug Metab Dispos; 1995 Jul; 23(7):736-48. PubMed ID: 7587963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes.
    Weaver RJ; Thompson S; Smith G; Dickins M; Elcombe CR; Mayer RT; Burke MD
    Biochem Pharmacol; 1994 Mar; 47(5):763-73. PubMed ID: 8135852
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regional distribution of drug-metabolizing enzyme activities in the liver and small intestine of cynomolgus monkeys.
    Nakanishi Y; Matsushita A; Matsuno K; Iwasaki K; Utoh M; Nakamura C; Uno Y
    Drug Metab Pharmacokinet; 2011 Jun; 26(3):288-94. PubMed ID: 21273732
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine.
    Uehara S; Murayama N; Nakanishi Y; Nakamura C; Hashizume T; Zeldin DC; Yamazaki H; Uno Y
    Xenobiotica; 2015 Feb; 45(2):124-30. PubMed ID: 25138712
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans.
    Iwasaki K; Murayama N; Koizumi R; Uno Y; Yamazaki H
    Drug Metab Pharmacokinet; 2010; 25(4):388-91. PubMed ID: 20814160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
    Sadrieh N; Snyderwine EG
    Carcinogenesis; 1995 Jul; 16(7):1549-55. PubMed ID: 7614688
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans.
    Shimada T; Mimura M; Inoue K; Nakamura S; Oda H; Ohmori S; Yamazaki H
    Arch Toxicol; 1997; 71(6):401-8. PubMed ID: 9195021
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cynomolgus monkey CYPs: a comparison with human CYPs.
    Iwasaki K; Uno Y
    Xenobiotica; 2009 Aug; 39(8):578-81. PubMed ID: 19622000
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation.
    Pearce R; Greenway D; Parkinson A
    Arch Biochem Biophys; 1992 Oct; 298(1):211-25. PubMed ID: 1381906
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H; Shimada T
    Arch Biochem Biophys; 1997 Oct; 346(1):161-9. PubMed ID: 9328296
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of various cytochromes CYP2B, CYP2C and CYP3A by phenobarbitone in non-human primates.
    Jones CR; Guengerich FP; Rice JM; Lubet RA
    Pharmacogenetics; 1992 Aug; 2(4):160-72. PubMed ID: 1306117
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N; Oda Y; Hase I; Asada A
    Br J Anaesth; 2001 Apr; 86(4):540-4. PubMed ID: 11573629
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes.
    Transon C; Lecoeur S; Leemann T; Beaune P; Dayer P
    Eur J Clin Pharmacol; 1996; 51(1):79-85. PubMed ID: 8880056
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Purification from liver microsomes from untreated cynomolgus monkeys of cytochrome P450 closely related to human cytochrome P450 2B6.
    Ohmori S; Shirakawa C; Motohashi K; Yoshida H; Abe H; Nakamura T; Horie T; Kitagawa H; Asaoka K; Rikihisa T
    Mol Pharmacol; 1993 Feb; 43(2):183-90. PubMed ID: 8429823
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone.
    Uehara S; Uno Y; Nakanishi K; Ishii S; Inoue T; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2017 May; 45(5):457-467. PubMed ID: 28196829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21.
    Nakamura A; Hirota T; Morino A; Imaoka S; Funae Y; Yamamoto Y; Tasaki T; Masuda M; Kazusaka A; Fujita S
    Xenobiotica; 1999 Mar; 29(3):243-52. PubMed ID: 10219965
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.