BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 21850047)

  • 1. Novel roles for hERG K(+) channels in cell proliferation and apoptosis.
    Jehle J; Schweizer PA; Katus HA; Thomas D
    Cell Death Dis; 2011 Aug; 2(8):e193. PubMed ID: 21850047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
    Thomas D; Karle CA; Kiehn J
    Curr Pharm Des; 2006; 12(18):2271-83. PubMed ID: 16787254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [HERG K+ channel, the target of anti-arrhythmias drugs].
    Guan FY; Yang SJ
    Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular determinants of cocaine block of human ether-á-go-go-related gene potassium channels.
    Guo J; Gang H; Zhang S
    J Pharmacol Exp Ther; 2006 May; 317(2):865-74. PubMed ID: 16397089
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The potent inhibitory effects of cisapride, a specific blocker for human ether-a-go-go-related gene (HERG) channel, on gastric cancer cells.
    Shao XD; Wu KC; Hao ZM; Hong L; Zhang J; Fan DM
    Cancer Biol Ther; 2005 Mar; 4(3):295-301. PubMed ID: 15846098
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Computational Models for Understanding of Structure, Function and Pharmacology of the Cardiac Potassium Channel Kv11.1 (hERG).
    Wacker S; Noskov SY; Perissinotti LL
    Curr Top Med Chem; 2017; 17(23):2681-2702. PubMed ID: 28413954
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Propofol inhibits hERG K
    Han SN; Jing Y; Yang LL; Zhang Z; Zhang LR
    Eur J Pharmacol; 2016 Nov; 791():168-178. PubMed ID: 27575519
    [TBL] [Abstract][Full Text] [Related]  

  • 8. State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy.
    Ganapathi SB; Kester M; Elmslie KS
    Am J Physiol Cell Physiol; 2009 Apr; 296(4):C701-10. PubMed ID: 19244476
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Progesterone impairs human ether-a-go-go-related gene (HERG) trafficking by disruption of intracellular cholesterol homeostasis.
    Wu ZY; Yu DJ; Soong TW; Dawe GS; Bian JS
    J Biol Chem; 2011 Jun; 286(25):22186-94. PubMed ID: 21525004
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration.
    Afrasiabi E; Hietamäki M; Viitanen T; Sukumaran P; Bergelin N; Törnquist K
    Cell Signal; 2010 Jan; 22(1):57-64. PubMed ID: 19765650
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias.
    Potet F; Lorinc AN; Chaigne S; Hopkins CR; Venkataraman R; Stepanovic SZ; Lewis LM; Days E; Sidorov VY; Engers DW; Zou B; Afshartous D; George AL; Campbell CM; Balser JR; Li M; Baudenbacher FJ; Lindsley CW; Weaver CD; Kupershmidt S
    J Biol Chem; 2012 Nov; 287(47):39613-25. PubMed ID: 23033485
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In silico prediction of the chemical block of human ether-a-go-go-related gene (hERG) K+ current.
    Inanobe A; Kamiya N; Murakami S; Fukunishi Y; Nakamura H; Kurachi Y
    J Physiol Sci; 2008 Dec; 58(7):459-70. PubMed ID: 19032804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.
    Limberis JT; Su Z; Cox BF; Gintant GA; Martin RL
    Clin Exp Pharmacol Physiol; 2006 Nov; 33(11):1059-65. PubMed ID: 17042915
    [TBL] [Abstract][Full Text] [Related]  

  • 14. H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.
    Jo SH; Hong HK; Chong SH; Lee HS; Choe H
    Pharmacol Res; 2009 Nov; 60(5):429-37. PubMed ID: 19497368
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclovirobuxine D inhibits the currents of HERG potassium channels stably expressed in HEK293 cells.
    Zhao J; Wang Q; Xu J; Zhao J; Liu G; Peng S
    Eur J Pharmacol; 2011 Jun; 660(2-3):259-67. PubMed ID: 21497594
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.
    Huang XP; Mangano T; Hufeisen S; Setola V; Roth BL
    Assay Drug Dev Technol; 2010 Dec; 8(6):727-42. PubMed ID: 21158687
    [TBL] [Abstract][Full Text] [Related]  

  • 17. hERG Channels: From Antitargets to Novel Targets for Cancer Therapy.
    Arcangeli A; Becchetti A
    Clin Cancer Res; 2017 Jan; 23(1):3-5. PubMed ID: 27903676
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HERG K+ channel blockade by the novel antiviral drug sophocarpine.
    Zhao XL; Qi ZP; Fang C; Chen MH; Lv YJ; Li BX; Yang BF
    Biol Pharm Bull; 2008 Apr; 31(4):627-32. PubMed ID: 18379053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The molecular determinants of R-roscovitine block of hERG channels.
    Cernuda B; Fernandes CT; Allam SM; Orzillo M; Suppa G; Chia Chang Z; Athanasopoulos D; Buraei Z
    PLoS One; 2019; 14(9):e0217733. PubMed ID: 31479461
    [TBL] [Abstract][Full Text] [Related]  

  • 20. hERG K(+) channels: structure, function, and clinical significance.
    Vandenberg JI; Perry MD; Perrin MJ; Mann SA; Ke Y; Hill AP
    Physiol Rev; 2012 Jul; 92(3):1393-478. PubMed ID: 22988594
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.